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Summary Expression Gene Literature (2) GO Terms (8) Nucleotides (316) Proteins (48) Interactants (292) Wiki
XB-GENEPAGE-952668
Gene Symbol:
pdha1

Gene Name:
pyruvate dehydrogenase E1 alpha 1 subunit

Synonyms:
pdha , phe1a , pdhce1a , pdha1-a , pdha1-b ( Add synonyms , Nomenclature history )

Gene Function:
metabolic complex component

Protein Function :
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


InterPro :
WD40 repeat CS , WD40 repeat dom sf , WD40 repeat , WD40 repeat dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
pyruvate decarboxylase deficiency

OMIM:
PYRUVATE DEHYDROGENASE E1-ALPHA DEFICIENCY; PDHAD

External Links:
 
Xenbase Gene ID XB-GENE-952669 XB-GENE-952676 XB-GENE-6253873
Gene Symbol pdha1 pdha1.L pdha1.S
Chromosome Chr02 chr2L Scaffold42224
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model
Entrez Gene 549826
446473
447434
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine pdha1 pdha1.L pdha1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PDHA1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pdha1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pdha1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pdha1b pdha1a ZFIN Ensembl
chicken
GEISHA PDHA2 Ensembl
fruit fly
worm
Publications
First An integrated genetic and man-mouse comparative map of the DXHXS674-Pdha1 region of the mouse X chromosome., Genomics 1998  
Most Recent Deep ancestry of mammalian X chromosome revealed by comparison with the basal tetrapod Xenopus tropicalis., BMC Genomics 2012            
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 3 terms 3 terms
PANTHER pdha1
KEGG Pathways K00161 K00161 K00161
KOG [C] Pyruvate dehydrogenase E1, alpha subunit
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pdha1
ORFs pdha1 ORF1 pdha1.L ORF1 pdha1.S ORF1 , pdha1.S ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

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