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Summary Expression Gene Literature (148) GO Terms (19) Nucleotides (183) Proteins (29) Interactants (808) Wiki
XB-GENEPAGE-952865
Gene Symbol:
pc.1

Gene Name:
pyruvate carboxylase, gene 1

Synonyms:
pcb , pyruvate carboxylase , MGC68971 ( Add synonyms , Nomenclature history )

Gene Function:
Pyruvate carboxylase

Protein Function :
Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


Interactants:
Loading ...

Diseases: 


Disease Ontology:
pyruvate carboxylase deficiency disease

OMIM:
PYRUVATE CARBOXYLASE DEFICIENCY

External Links:
 
Xenbase Gene ID XB-GENE-952866 XB-GENE-952869 XB-GENE-17334394
Gene Symbol pc.1 pc.1.L pc.1.S
Chromosome scaffold_4 chr4L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 7.1 Version 9.2
CDS Gene model
Entrez Gene 398811
mRNA RefSeq
Protein NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pc.1 pc.1.L pc.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pcx MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pc Ensembl
zebrafish
ZFIN, AGR pcxb ZFIN Ensembl
chicken
GEISHA PC Ensembl
fruit fly
FLYBASE Pc Ensembl
worm
Publications
First The nucleotide sequences of 5.8-S ribosomal RNA from Xenopus laevis and Xenopus borealis., Eur J Biochem 1978  
Most Recent Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos., Sci Rep 2017          
All View All Papers 12 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 8 terms 0 term
PANTHER pc.1
KEGG Pathways K01958
KOG [C] Pyruvate carboxylase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks
ORFs pc.1.L ORF1
Clones Horizon
Plasmids Addgene Addgene

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