[provisional- machine annotated only] Gene Symbol: fbxo5 [Predicted: Source is Human Entrez Gene] Gene Name: F-box protein 5 [Predicted: Source is Human Entrez Gene] Synonyms: emi1, fbx5 Add Xenopus synonyms Gene Function: Interactants: ccnb1.2(11) , cdk1(9) , cdc20(8) , btrc(6) , fbxo43(6) , pold1(6) , plk1(5) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001044469|Xenopus (Silurana) tropicalis F-box protein 5 (fbxo5), mRNA ACCTACCTATCAATATGATGTGCGGATTCACCAGTAACCAGTCTCCAAAAAAGCTCTCTTCAAAAAAATTGAGTGCCACCAATGTTCACTTAGAAATTAGTCCAGTCAAGTGTGACAGTCCATGCAAAGGCTATGAAAATGTACAAGCCTCCTATTTGGATACTGCGAATTGCACAACAGTTACAAGAGGTGCAGACATCAAAGATGATCTGCCTTTACACAACAAGGAGAATCTTTTGCATAGATTTGGTGATTTAGAAACGCACAGTGATGAAGAATATAGTGGATTGCAAGACAGTGGCTATTCATCAATACTGCAAAATGACTCACCGTGTCAAGATGAAACAGATAACAATGTGTCAGATATTCAACTACGCGAAACGCCAAAGAATTTTGTGCAGTTCCAAAAACCTCTCCATACTTTATCTACAAAAAATTTGCCAGCCCTTCGTTTTGAAGAAGCTATGTGTTCTACGCTGAAGAAAATGAGAAAAACAAGTAAAAAAATTGACTGGAATGCTGTTGATGATGTAGTTTGTGGTGGGAACTATGGTCTTGAGAATCTGATTGGCAAGAATATGGGATTGGAAAGATTTGATATCCTTGCAGAACTTTTTCATCGAGACTTCAAGCATTTGCTGACTAAAATTTTAAGGCACCTTAGTGCAATGGATTTGATAAATGTCATCAGCGTGAGCACAACATGGAGAAAAATACTACAAAAAGATAACTCGGCCTACAATTCTTACAAATTAGGATGCAAGGAGCTTTGTGAAAAGAAAGCCAAAGTATCTGCCCACACTGCAACCCGTGACGAGTCTCTCTGCCGTGTGCCTTTGGCGTCTGTTCAAAAAGTAGCAGCTTCGTCTCTCTGCACATCAAAAAAGCAGAGTAAGAACAGAGGCCTGTCTAATAACAGACATGCAGAATTTATTGAGGTTGCTCAGACTTTAAAGAATGACCAATGCCTTAAGGTTTGTGTAGACTGCAGCTCTCCAGCTAAATATGACCCATACCTTCATCGTGCCACCTGCACAAGAGAAAGCTGTAAATTTGACTTTTGCACGCTTTGCTCTTGTAAATATCACGGTTCAAAATGCTGCCAGACAAGCAAGCCACGGAGTTATCGAGTTCCTTCAGAGCCATTGCCCGGCAGCAAAAAAAGCAAACAGAACTTACGGAGGTTGTAGTTTAGGATATATGAATTTAAGTCACATTGTTGGTATACATATTTTACTACATATTTTAAAAAGGAAATATATGTATATGTGCTCTGCTATCTACGTTTTAGTATTTTAATGGAGCTATACGTTTTATGCCTTTTATTTTGCTTACTCTTAATGTTTAAATAGTCTAATTGGTGAATTCAAAAATCAACTTGGGTCAAGTTCGCTATGGCCTATTTTTTTTTTTTTTTTATTTCCAAACAAGATTTTGGATTTCTAAGCTTTTATGTATTGATATCTCTTATAAGGGATCACCAATAAGAATTGCTTTTCTCATTGAGGGAAAATGTATTTATTATATATTTGCCTTTTAGAGCAAAGTTTGTAAATAGATGTAAATACGTATTATGTGAGTCTGTTCATTTATGTGTTCTATGGTTCCCCTCTGTGTGCAGTATATTTTGCACTGCTTAATAAATTATTGCAAAATCTTTGATTTAAAAAAAAAAAAAAAAAA	Refseq >NM_001088653|Xenopus laevis F-box protein 5 (fbxo5-a), mRNA ATCGAATTCCCCGGGGATTGTGGGTGTTTTTAACAGGCTAGGGGGAATAACGAAAGCGGGAGCTATGCGAGAGGGGTGTTATGGAAAAATCAGATCGCTTTTAAACACCGTATTCTTTTTTTAATTTTTTTGGTAAATGATCTTGAGAAGTGGGCGCTTCGGAAAAGCGTGATATTTTATCCAGAATACAGGTTTCAGCCTATCGGGTCCTGACCTACCTATCAATATGATGTGCGGATTTGCAAGTAACCAGTCTCCAAAAAAGCTATCTTCAAAAAAATCAAGTGCAACTAATGTTCACTTAGAAATTAGTCCAGTGAAGCATCACCCTCCATGCAAAGTCTATGAAAATGTGCAAGGCTCCTGCTTGGATAGTGCAATCTGCACAACAGTTGCAAAGTGTGCAGACCTTACAGATGATCTGCCTGTACACAACAAGGAGAATCTTTTGCATAGACTTAATGATTTAGAAACAAACAGTTATGAAGAATATAGTGCATTGCAAGATAGTGGTTATTCGTCAATACTGCAAAATGACTCTCCATGTCAAGATGAAACAGACCGGAAAGTTTCAGATATTCAAGTACGTGAAACACCAAAGAATTTCATGTCATACCAAAGACCCTTCCATACTTTATCTAAAATAAATTTGCCGATCCTTCGTTTTGAAGAAGCTGTTTGTTCTACGCTGAAGAAAATGAGAAAAACAAACAAAAAAATTGACTGGAATGCTGTTGATGTCGTTTGTGGTGGAAACTATGGACTTGAGCATCTGATTGGCAAAAGTATGGGACTGGAAAGATTCGATATACTTGCAGAACTTTTCCATCGAGATTTCAAGCATTTGCTGACTAAAATTTTAAGGCACCTTAGTGCAATGGATTTAATAAATGTCATCAGTGTGAGCACAACATGGAGAAAACTGCTGCAGAAAGATAACTGGGCCTACAATGCTTATAAATTAGGATGCAAGGAGCTTTGTGAAAAGAGAGCCAAAGTATCCAGCCACACTGCAACCCGTGATGAGTCTCTCTGCCGTGTGCCTTTAGCATCTGTTCAAAAAGTAGCAGCGTCCTCTCTCTGCACATCAAAAAAACAGAGCAAGAATAAAAATGGAGGCCTGTCTTGTAACAGACTTGCAGAATTTATTGAGGTTGCTCAAACTTTAAAGAATGACCAAAGCCTTAAGGTTTGTGTAGACTGTGGCTCCCCAGCTAAACATGACCCTTGCCTTCATCGAGCCATCTGCACAAGAGAGAGCTGTAAATTGGACTTTTGCACCCGTTGCTCTTGTAAATATCACTTTTCAAAAAGCTGCCTGATGAGTAAGCCAGGGAGTTATCGAATTCCTTCAGAGCCATTGCCCGGGAGCAAAAAAAGCAAACAGAATTTACGGAGGTTATAGTTTAAAATTAATTTAAATCCTGTTTTGGGTATATTCAAAAGTGTCTATACGTATTTTAATATATGTGTATGTGTGTGTGTGTGCGCCATCATCTACGTTTTAGTATTTTAATGGAGCATTTGTTTTATTAATTTTCTTACTCTTAATGTTAAAATAGGAGTCTTGTTTAAAAATCAAATTGTTTCTTCGTAGGTACAATATATTTTATATTTCCAAACAAGATTTGGCATTTATCATGTATATCTATATGAAATATATATATATATATATATATATATATATATATTTATATTTGATCTCTTATAAGGGATCACTGCTTTTCTAATTGGGGAAAAATGTATTTTCTAAATACTGTATATATTTGCATTTTTGCGCAAAGTTTTGTAAATATGTTCATTTATATGTGCTCTATGGTTCGCTCTGTGTGCAGTATATTTTTCTGTGCTAAATAAATTATTGCAATTAAAAAAAAAAAAAAAAAAA		Refseq >NM_001096012|Xenopus laevis F-box protein 5 (fbxo5-b), mRNA GAAAAATTAGAACGATTTTAAACACATTCTTTTTATTTTTGGTAAATGATCGTAAGGCGTAGGCGCTCCGGGAAAGCGTGATATTTTATCCAGAATAAAGATTCCAGCCTTTCGGGTCCTGTCCTACCTATCAATATGATGTGTGGATTTACAAGTAACCCATCTCCGAAAAAGCTCTTGTCAAAATCAAGTGCAACCAATGTTCACTTAGAAATCAGTCCAGTCAAACCTGACCGTCCATGCAAAGGCTATGAAAATGTGCTAGGCTCCTGCACAACAGTTGCAAAGTGTGCAGACCTTACAGATGATCTGCCTGTACACAACAAAGAGAATCTTTTACATGGATTCAATGATTTAGAAAGACACCATGATGAAGAAAATAGTTCATTGCAAGATAGTGGTTATTCATCAATACTGCAAAATGACTCTCCATGTCAAGATGAAACAGACAGTAATGTGTCAGATATTCAAGTACGTGACACGCCAAAGAATCTCATGCAGTACCAAAAACCCTTTCATACTTTATCTACAAGATGTTTGCCGATCCTTCGTTTTGAAGCAGCCATGTGTTCTACGCTGAAGAAAATGAGAAAAACAAGTAAAAAAATTGACTGGAACGCGGTTGATGATGTCGTTTGTGGTGGAAACTATGGTCTTGAGCATCTGATTGGCAAAAGTATGGGATTGGAAAGAGTAGATATCCTTGCAGAACTTTTCCATCGAGACTTCAAGCATTTGCTGACTAAAATTTTAAGGCACCTTAATGCAATGGATTTAATAAATGTCATCGGTGTGAGCACAACATGGAGAAAAATACTACAAAAAGACAACTGGGCCTACAATACTTACAAATTAGGATGCAAGGAACTTTGTGAAAAGCGAGCCAAAGTATCCACCCACACTGCAACCCGTGATGAGTCTCTCTGCCGTGTGCCTTTAGCATCTGTTCAAAAAGTAGCAGCGTCCTCTCTCTGCACATCAAAAAAGCAGAATAAAAATGGAGGCCTGTCTAATAACAGACATGCAGAATTTATTGAGGTTGCTCAGACTTTAAAGAATGACCAAAGCCTTAAAGCTTGTGTGGACTGTGGCTCCCCAGCTAAATATGACTCCTACCTTCATCGTGCCATCTGCACACGAGAGAGCTGTAAATTGGACTTTTGCACACTTTGCTCTTGTAAATATCACTCTTCAAAAAGCTGCCTGATAAGTAAGCCGAGGAGCTATAGAATTCCTATAGAGCCATTGCCCGGAAGCAAAAAAAGCAAACAGAATTTACGGAGGTTGTAGTTTAGTAAAAATGAATTTAAATCACATTATGGGTATAGTCATAAAGTGTCAAAATACACATTTTAAAATATATACATACATGTATGTATGTGCTCCGTTATCTACGTTTTAGTATTTTAATGGAGCAATAGTTAGATTCATTTATTTTGCTTACTCTTAATGTTAAGATAGAAGTCTTATTGGTGAATTTAAAAATCAATTTGCATCTTAGGTACAATCTTTTTATATTTCTAAGCTTTTATATATACATATTGTTATCTCTTATAAGGGATCACCCATAGGAATTGCTTTTCTCATTGGGGAAAAATGTATTTTTTAATATATTTGCCTTTTTGGGCAACGTTTTGTAAATATGTATTATGTGAGTCTGTTTCTTTTATATGTTCTCTATGGTTATCTCTGTTTGTGTGCAGTATATTTTGCGCTGCTAAATAAATTATTGCAATTCAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001037934|F-box only protein 5 [Xenopus (Silurana) tropicalis] MMCGFTSNQSPKKLSSKKLSATNVHLEISPVKCDSPCKGYENVQASYLDTANCTTVTRGADIKDDLPLHNKENLLHRFGDLETHSDEEYSGLQDSGYSSILQNDSPCQDETDNNVSDIQLRETPKNFVQFQKPLHTLSTKNLPALRFEEAMCSTLKKMRKTSKKIDWNAVDDVVCGGNYGLENLIGKNMGLERFDILAELFHRDFKHLLTKILRHLSAMDLINVISVSTTWRKILQKDNSAYNSYKLGCKELCEKKAKVSAHTATRDESLCRVPLASVQKVAASSLCTSKKQSKNRGLSNNRHAEFIEVAQTLKNDQCLKVCVDCSSPAKYDPYLHRATCTRESCKFDFCTLCSCKYHGSKCCQTSKPRSYRVPSEPLPGSKKSKQNLRRL UniProtKB	Refseq >NP_001082122|F-box only protein 5-A [Xenopus laevis] MMCGFASNQSPKKLSSKKSSATNVHLEISPVKHHPPCKVYENVQGSCLDSAICTTVAKCADLTDDLPVHNKENLLHRLNDLETNSYEEYSALQDSGYSSILQNDSPCQDETDRKVSDIQVRETPKNFMSYQRPFHTLSKINLPILRFEEAVCSTLKKMRKTNKKIDWNAVDVVCGGNYGLEHLIGKSMGLERFDILAELFHRDFKHLLTKILRHLSAMDLINVISVSTTWRKLLQKDNWAYNAYKLGCKELCEKRAKVSSHTATRDESLCRVPLASVQKVAASSLCTSKKQSKNKNGGLSCNRLAEFIEVAQTLKNDQSLKVCVDCGSPAKHDPCLHRAICTRESCKLDFCTRCSCKYHFSKSCLMSKPGSYRIPSEPLPGSKKSKQNLRRL UniProtKB		Refseq >NP_001089481|F-box only protein 5-B [Xenopus laevis] MMCGFTSNPSPKKLLSKSSATNVHLEISPVKPDRPCKGYENVLGSCTTVAKCADLTDDLPVHNKENLLHGFNDLERHHDEENSSLQDSGYSSILQNDSPCQDETDSNVSDIQVRDTPKNLMQYQKPFHTLSTRCLPILRFEAAMCSTLKKMRKTSKKIDWNAVDDVVCGGNYGLEHLIGKSMGLERVDILAELFHRDFKHLLTKILRHLNAMDLINVIGVSTTWRKILQKDNWAYNTYKLGCKELCEKRAKVSTHTATRDESLCRVPLASVQKVAASSLCTSKKQNKNGGLSNNRHAEFIEVAQTLKNDQSLKACVDCGSPAKYDSYLHRAICTRESCKLDFCTLCSCKYHSSKSCLISKPRSYRIPIEPLPGSKKSKQNLRRL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.44195	Xl.11644		Xl.39598
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	FBXO5
mouse		MGI	Fbxo5	All(3) Targeted, knock Out(1) Targeted, other(1)
zebrafish		ZFIN	fbxo5	10 Lines(s)

Publications
First:		Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. [Cell 2001]
Most recent:		The APC/C inhibitor XErp1/Emi2 is essential for Xenopus early embryonic divisions. [Science 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		rhodopsin-like receptor activity
Biological:		G-protein coupled receptor protein signaling pathway
Cellular Component:		integral to membrane
EC:
KOG:

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.10791.1.S1_at [+] Str.44195.1.A1_x_at	Xl.11644.1.S1_at
Affymetrix 2.0			Xl2.11644.1.S1_s_at		Xl2.39598.1.S1_at

Symbol legend[+]

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