[provisional- machine annotated only] Gene Symbol: ldlrap1 [Predicted: Source is Human Entrez Gene] Gene Name: low density lipoprotein receptor adaptor protein 1 [Predicted: Source is Human Entrez Gene] Synonyms: arh, arh1, arh2, fhcb1, fhcb2, xptb Add Xenopus synonyms Gene Function: Adaptor protein CED-6, contains PTB domain Interactants: tfap2a(2) , a2m(1) , alb(1) , ambp(1) , arrb1(1) , arrb2(1) , bmp15(1) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001017114|Xenopus (Silurana) tropicalis low density lipoprotein receptor adaptor protein 1 (ldlrap1), mRNA AGGGAGAGGGGAAAAGTTTGCGGGACTTGGAAAGTTCGTGAGTGGAGCCGAGCGGGGAGATGGATGCACTCAAGTCTGCGGGAAGGGCGATCATTAGGAGTCCGAGTATTGCCAAGCAGAGTTGGGGAGGAGGCAAACATAAGAAACTGCCAGAAAACTGGACTGATACCAGAGAAACTCTCTTAGAAGGAATGTCATTCCATTTGAAATATTTGGGGATGACACTAGTGGAACAACCAAAAGGGGAAGAGCTGTCAGCAACTGCTGTGAAAAGAATCGTGGCAACTGCCAAAGCAAGTGGCAAGAAACTGCAGAAAGTTATTCTGAAAGTATCACCACGTGGAATCATTTTGTATGACCTTGCAAGTAACCAGCTGATTGAGAATGTTTCAATATACAGGATATCATATTGCACAGCTGATAAAATGCATGACAAAGTTTTTGCCTATATTGCTCAGAGCCAGCAGAATGAAACCTTGGAGTGCCATGCATTTCTCTGCACAAAGCGGAAAATGGCACAAGCAGTCACATTAACGGTGGCTCAGGCTTTCAAGGTAGCATTTGAGTTTTGGCAAGTATCCAGAGAGAATAAGGAAAAGAGAGAGAAATCTGGTTCAGATGGGGAGGGAGCAAGTAGTTCTCAATCTGATGGCTCCTCAAGTATCACCAGCCTTAAAGCATCAGCATCTGCAAACCTTTTGGATTTGGAAGACTGTGCCAAAGCTTTTGATGCATTAAATGCCAGTGACAATCATATTGAAGATCTATTTAGGCAAAATGAGTCCAATGAAAACAACAATATTGTGTGGGCATTGGATGATGGACTAGATGAGGCTTTTTCAAGGCTTGCAGAATCCAGAACCAACCCTCAAGTGCTTGATATCGGACTGACTGCAAATGACCTTCAGTCTGAAGAGTGCTTGTCTCCTTCCAGCTGGGATAAGTTGGAGTTGAACCCTGCCGAAGCAGATGAACTATTTATGTTCTGACCTTTCTGAAGCTACCTGCCAATTTTCAGTGCAATAGTCCTACCATCAGGCTCCTGTCAGTGTTTCAAGAACAAATGTAATTGCTGAGAAGCTGTACACCTTGACGTGGGATTTGAAAACCAAAGCATTACCTTAAGACACTTTATTACCTTGTTCTTCAAAAACTAAAGGAAAAGATGCATGTGTTAGATAAACCATGTGTGTTTCTTGAATCTTACATTCTGGAGCAAGACCCAGACACCACCAGGTTATATTTTGGGGGTACAGAGTCTTCAAGAATTCTTGGGAACATGGATTTTGTTTGTGGAAAGTTGTTACTTTTTTACTTTTTGTACAAAATACTGGATAGATTCTCCATGTTCTAAAGGCCCCTTTTTCCATATCTTTCATTAAATGAACTATTTGTTTAACTACCATAAAAAAAAAAAAAAAAAA	Refseq >NM_001089091|Xenopus laevis low density lipoprotein receptor adaptor protein 1 (ldlrap1-a), mRNA CCCGCTGGCAGGGAGGGAGAGGGAAAAAAGTTTGTGGGACTCGGAAAGTTTGTGGAGTGGAGCCGAGCGGGGAGATGGATGCACTCAAGTCTGCGGGGAGGGCGATCATCAGGAGTCCGAGCATTGCCAAGCAGAGCTGGGGAGGAGGCAAGCACAAGAAACTGCCAGAAAACTGGACCGATACCAGGGAAACACTCTTAGAAGGAATGTTATTTCATTTGAAATATTTGGGCATGACATTGGTAGAACAGCCGAAAGGGGAAGAGCTGTCTGCAACTGCAGTGAAAAGAATTGTGGCAACTGCCAAAGCAAGCGGGAAGAAACTGCAGAAAGTTATTCTGAAAGTATCCCCACGGGGCATCATTCTGTATGACAGTACAAGTAACCAACTAATTGAGAATGTTTCGATCTACAGGATATCCTATTGCACAGCTGATAAAATGCATGACAAGGTTTTTGCCTACATTGCGCAGAGCCAGCAGAATGAAACCTTGGAATGTCATGCATTTCTCTGCACAAAAAGGAAAATGGCACAAGCAGTCACATTAACCGTGGCTCAAGCTTTTAAAGTAGCATTTGAGTTTTGGCAAGTATCCCGAGACAAAACGGAAAAGAGAGAGAAGTCTGGTTCAGGTGGAGAGGGGGCAAGTAGTTCTCAGTCTGATGGCTCCTCAAGTATCACCAGTCTTAAAGCCTCGGCTTCTGCAAACCTTTTGGATTTGGAAGACTGTACCAAAGCTTTTGATGTGTTAAATGCCAGTGACAATCATATTGAAGATCTATTTAGGCAAAATGCATCCAATGAGAACAACAATATTGTGTGGGAATTGGATGATGGACTGGATGAGGCCTTTGCAAGGCTTGCCGAATCCAGAACAAACCCTCAAGTCCTCGATATCGGACTGACTGCAAATGACCTTCAGTCTGAAGAGTGCTTGTCTCCTTCCAGCTGGGATAAACTGGAGTTGAACCCTGCAGAAGCAGATGAACTATTTATGTTCTGACACTTCTGAAGCTACCAGCCAATTTTCAGTGCAATAGTCCAACCATCCGACCCCTGTCAGTGTCTCAAGAGCAAATCTAGTTGCGAAGCATCTGTACACCTTCAGGTGGGATTGGAAAAACCAAAGCTTTACCTTAGACACTTTATTTCCACATTTATCACAAACGAAAGGAAAAAAGTTTCTGATAAAACCATATGTTTCTTGAATCATGCATTCTGGAGCAACACCGAAAAACCAGCAGGTGATATTTTTAGGGGTACACAGTCCTCAAGAATTCTTGGGAACATGGATTTTTTTTGTGGAAAGTACCTTTTACTTTTTGTGCAAAATACTGGACAAATCCTTCATGTTCTAATCCTTTTTTCCATATCTTTCATTAAATGAACTACACATTTCACTACCATAAGATATACGTGGCTGTGGCATAGTGTTTTGTGTTTAGATATTTTGTGTTTATATATGTTAAAATTCTTGCGTTTATTCACATTGGTGTTCCCATACCATATGGTATCAGTCCTGTAACGTTCTAGCACCAATTCTGCAGTTGTGCACAGCTGCTATATGTGTATGGATGCTTAATTGGCTATAGAACGTCTGATTTTCCTCCTTTTCTTAGTCTTAACGGGTTGCTTTGTGACCTTCATTATTGTACTTCAATGTGTTTTATATTAACATATTTACTAGCTATCACTCATCTAATTAGAGCACTTAAATTTATTTTTTATTTCCCTCTCGCTCACAAATATTAGTCCACATGTTCATTCCTCCATAGTCTTAAGTATTGCCAGCTTTTGAGATTCCAGCTTGCTTTTCGGCTACATACCATTCAAACGAGACTAACGGCATGTTGCACAGTATTATGAAACCTATGCATTTTTTGTCTGCACCCAGAGTTGACAATCAATCTTTTTGTAATGGACAATATGTACCCCATATTTTTTTGTCTGCAGTTGTTTGCTTATAATACTTTTTAATTGTATCCTTGAAAAATGTATAAATTAACGTTTGTTTTTTGCTATCGTAAATCTAAAGTGGGTATTTAAGGGTGATATGAATATGTGCATTTTTAAATCTTATGGAGTTTCGTTGTACGCGGAGTTCTTAAATTTTTTCATGGATGAAAGTATTTGATAGCCTCAAAGTAAATCTGACCCGTATTAAGGAGTATAATATCTACTAACATCTAGTCCATGTTCATTAGCACTACCTATTCTATTCAAAATTGTTCTGGGTTGAGCTGTTAGTGCAGGGGGTGTTTGGTTTTCCTAGGTAAAATGGCCAGCTCCTTATGTATAATGTTTCCTGAAGCCATTTTAGAACCAAAGTAACTGCTATTTTACTCGTGCTCTGTTTAACAATGTTGAATAACAACTAGGCAATTCTATTTACAACATGGCAATTCTATTACATATAAAGCTATAGTAATGGAGGTGAAAATCAGGCAAATTTTGGGAAAACTAGACATGAAATGGCTGCAAATTGTCCACCACATTTTTAATGTAATTCACATGAACGTTATTTTAACGGCCATAAATGTAACATGAGAATGCATCTGTGCAGCATGCAGACTGGGTATTTCTATCATTTGTAGCTCAATACACCCAGGCCTTGCACCTTGGGATTCATGACCATACGTTTCTAAAGCACTATCTTACTGGAGGTTTTTTATCTTACACCTTTCGTTTGGTCTTCCCTGCCGTGTCATGTGAAAAGAGCAAAAATTTATGGTATTTTACACAACAGGAAGCGTTTTCTTCACAGGCAGACTTTATACGTAGCTATGCATTTTAAGCATTAACAGTTATTTATATTAATACCAATGGCTTCATAAATAAATATGGTTTAAAAGCCACAGGTAAACAGATGGAGGCTACAGATTGACTATCCTTCATGTATTAGTTCAGTTTGGGAAACACCCTAAATCTTCACCACTTCAACACCCTTTATGTTCTTGAACTGTTACAAAATCCGGTTGCTCCTTCAACCATGCCTTTAAAATATGGAAGTAAAATCACAATGTTAAACAGCACATGGGGGTAATGTTCCTTTAATCTTCTCTTAGCTTCCAGCTCTCCACACATTCTGCTGTACTGTAAATATTGGCAATATTTAAAATGCTATTGACAATGTATCGGAAACCAGAATAAATATTTTTGGTTTAATGTCAAAAAAAA		Refseq >NM_001091098|Xenopus laevis low density lipoprotein receptor adaptor protein 1 (ldlrap1-b), mRNA CCCTGCTGACAGGGAGGGAGAGGGAAAAGTTTGAGGGGCTTGGAAAGTTCGTGAGTGGAGCCGAGCAGGGAGATGGATGCGCTTAAGTCTGCTGGGAGGGCGATCATCAGGAGTCCGAGCATTGCCAAGCAGAGCTGGGGAGGAGGCAAGCACAAGAAACTACCAGAAAACTGGACTGATACCAGGGAAACACTCTTAGAAGGAATGTTATTCCATTTGAAATATTTGGGCATGACATTGGTGGAACAACCAAAAGGGGAAGAGCTGTCTGCAACTGCAGTGAAAAGAATTGTGGCAACTGCAAAAGCAAGTGGGAAGAAACTGCAGAAAGTTCTTCTGAAAGTATCACCACGGGGCATCATTCTGTATGACAGTGCAAGCAACCAACTAATTGAGAATGTTTCAATCTACAGGATATCATATTGCACAGCTGATAAAATGCATGACAAAGTTTTTGCCTACATTGCTCAGAGCCAGCAGAATAAAACCTTGGAATGCCATGCATTTCTTTGCACAAAGAGGAAAATGGCACAAGCAGTCACATTAACGGTGGCTCAGGCTTTCAAGGTAGCATTTGAGTTTTGGCAAGTATCCCGAGAGAATAAGGACAAGAGAGAGAAGTCTGGTTCAGATGGAGAGGGTGCAAGTAGTTCTCAGTCTGATGGCTCCTCCAGTATCACCAGCCTTAAAGCATCAGCATCTGCAAACCTTTTGGATTTTGAAGACTGTACCAAAGCTTTTGATGTGTTAAATGCCAGTGATAATCATATTGAAGATCTATTTAGGCAAAATTCAACCAATGAGAACAACAATATTGTTTGGGAACTGGATGATGGACTGGATGAGGCATTTGCAAGACTTGCAGAATCCAGAACAAACCCTCAAGTCCTTGATATTGGATTGACTGCAAATGACCTTCAGTCTGAAGAGTGCTTGTCTCCTACCAGCTGGGATAAACTGGAGTTGAACCCTGCAGAAGCAGATGAACTATTTATGTTCTGACCTTTCTGAAGCTACCTGCCAATTTTCAGTGCAATAGTCCTACCATTAGACTCCTGTGTAGTTGCTGAGAATCTATACACCTTGAGGTGGGATTGGAAAACCAAAGCTTTACCTGAGACACTTTATTTCCAAGTTCATCACAAACTAAAGGGAAGAAAAATATTACTGATAAAACCGTATGTGTTTCTTGAATATTCCATTCTGAAGCAAGACCGGAAAACCAGCAGGCTATAGTGTAGGGGTGTGCAGTCCTCAAGAATTTTTGGGAACATGGATTTTGTTTGTGGAAAATTTTTTTTTTTTTACAATTTTGTACAAAATACTGGACAAATACTTAATGTTCTAAAGGCCCCCTTTTCCATATCTTTCATTAAATGAGCTACAAATTCACTACCATAAGATATACTTGTGTTGTGTTTGTTACGCTTAAAATTCTTAGTTTATTCACATCTGTGTTCCTATTAAAGCACCATATGGTATCAGTCCTGTATAACGTTCTAGCGCCGTTTATGCTCATCTGCTGTTTTGTAGGGCTGCTCATTGGCTATAGAACATCTGATTTTCCTCCTTTCCTTGTCTAAGTGGTTACTTTGTGACCCTAATATACTGGATAGCTAATTAGAGCTCTTAATTTATCCCCCCATAACGGATTCCCCGCTCACTCACAAAAAATGTTTATAAAGTCATAACACTAACCTAGCCTGCCTATTTTATCCATATGTTCATTCCTCCGTAGTCCAAAGTATTGCCAGTTTATGAGATTCCCAGCTTGCTTTTCAGTTCCATACCATTCAAATGAGACTATTGTGGCATCTTGCCATAAACGGTCTGCACAGTATTATGAAAAATATGCATATTTGTCTGAGTTGACAATCATTTTGTAATGGACAATATTTAACCCATATTTTGTTTGTCTGCAGTTGTTTACTAGAATACTTTTTTTTTTTTTTTTTAATTGTATTCTTGAAAAAAATGTGTGCATTAACGTGTTTGTTAGAATATTTTCTTTTTGCGCTGTTCTAAATCTAAAGTGGGCATTTAAGGGTGATATGAATGTTTCTTTGTGCATTTTTAAAAATTTGTATGGCGTTTCTTTGTATGCCAAGCTGTTAACAATTTTCTTTCATGGATGAATGGATTTGATAGTCTTGTTCTCAAAGTATAATATATCTACTTATAATACACCAAAGCCATGAATATCTTGTAAATGATATCCTTATAAACGGTGAGTTCTGATGTCATCTGTTAACGGTGATGTCATTTCTGTCGCATGACTCACTGAATCCTGTGTATTATAACAAATAATGTACCCCTGTGTTGCAAAATATGAGGATATTATAAGTTACCTCGGAGTTTCAACTCCTCAGTAACTTATAATATCCTTATTTGCAAAAGGGGGTACTTTATTCACTATATCTTATGCTACCTATTGCTATTCAAGATGGCTGTGGGTCGAGCTGTGACTGGCAGTGGCGGAACTACCGGGGGTGCGAGCGGGCCAGGGCCTGCACCCCTTCAGGGGCAGCCCATGCGCCGCTCAAAATGCGAGCTGTACGGAGGGGGTGGGGCCGGCTGCGCGTCATGCACCAGGGCCCGCCCCCCTCTAGTTACGCTACTGGGAGGAGGCATTGGTTTTCCTAGGTAAAATGTCCTGTTCCTTCGGTTTCCTGCAACCAACCAAAGAAATTTCTATTTTACTAATTCTCTGCTTGACTATTAAATAACAGCATGGCAATTCTATTTCAATATAAAGCTATATTTAATGGCAGTGAAAATCGGCCACATTTTGGTGAATCCATTTTGGGAAAACTAGATGTGAATGGTAAATTGTACACCACATTTTTAGTGTAATTAACATGCACATTATTTTAACGACCATGAAATGCGCATTAGTATGTCAAGAGTGCCTCTGTGCAGATAAAGTATTTCTATCATTTGTAGCTGGATACGCCCAGGCCTTGTCACGCTGATTTGCATACAATGTAATCTTGCCACCGGAAAGTGATTGTGATCATTGGTTTCTGAAGCAGTTATCTCGTCGGAAGGTTTTTTTTTTTTTTTCTTAAACATTTCATTTCAGATTTGGTCTGCTATAATGTCATATGAAGAGCAAAAACAATTTATTGCATTCACATTTCAGAAAGCCGATTTCACAGGCTAAGTATTAACAGATTATTTATTTAATGCCAAGTGGCTTCATTAATAAATTACTGGTTTAAAAATCAAAGGTAAAAACAAAACTTATGGCTGAACTGATGGAGGGCTACAAACTTCATGTATTAGATCAGTTTAGGAAGCACCCTAAATCTTTTATGTTCTGAACGGTTACAAAATGACAACAGATTTGTTTAAACACTTCACCTTCATCCTATTCCTTATTGTTTCTAAACTGTTACAATATCTGGTTTGTCCATAAACCATGCAAAAACAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001017114|low density lipoprotein receptor adaptor protein 1 [Xenopus (Silurana) tropicalis] MDALKSAGRAIIRSPSIAKQSWGGGKHKKLPENWTDTRETLLEGMSFHLKYLGMTLVEQPKGEELSATAVKRIVATAKASGKKLQKVILKVSPRGIILYDLASNQLIENVSIYRISYCTADKMHDKVFAYIAQSQQNETLECHAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSRENKEKREKSGSDGEGASSSQSDGSSSITSLKASASANLLDLEDCAKAFDALNASDNHIEDLFRQNESNENNNIVWALDDGLDEAFSRLAESRTNPQVLDIGLTANDLQSEECLSPSSWDKLELNPAEADELFMF	Refseq >NP_001082560|low density lipoprotein receptor adapter protein 1-A [Xenopus laevis] MDALKSAGRAIIRSPSIAKQSWGGGKHKKLPENWTDTRETLLEGMLFHLKYLGMTLVEQPKGEELSATAVKRIVATAKASGKKLQKVILKVSPRGIILYDSTSNQLIENVSIYRISYCTADKMHDKVFAYIAQSQQNETLECHAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSRDKTEKREKSGSGGEGASSSQSDGSSSITSLKASASANLLDLEDCTKAFDVLNASDNHIEDLFRQNASNENNNIVWELDDGLDEAFARLAESRTNPQVLDIGLTANDLQSEECLSPSSWDKLELNPAEADELFMF UniProtKB		Refseq >NP_001084567|low density lipoprotein receptor adapter protein 1-B [Xenopus laevis] MDALKSAGRAIIRSPSIAKQSWGGGKHKKLPENWTDTRETLLEGMLFHLKYLGMTLVEQPKGEELSATAVKRIVATAKASGKKLQKVLLKVSPRGIILYDSASNQLIENVSIYRISYCTADKMHDKVFAYIAQSQQNKTLECHAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSRENKDKREKSGSDGEGASSSQSDGSSSITSLKASASANLLDFEDCTKAFDVLNASDNHIEDLFRQNSTNENNNIVWELDDGLDEAFARLAESRTNPQVLDIGLTANDLQSEECLSPTSWDKLELNPAEADELFMF UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		[+] Str.48722	Xl.13266		Xl.8355 [+] Xl.71390
Unigene EST Profile			EST Profile		EST Profile
GEO data			GEO		GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	LDLRAP1	OMIM:603813
mouse		MGI	Ldlrap1	All(3) Targeted, knock Out(1) Gene Trapped(1) Targeted, other(1)
zebrafish		ZFIN ZFIN	ldlrap1b ldlrap1a

Publications
First:		ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2. [J Biol Chem 2002]
Most recent:		Identification of novel and known oocyte-specific genes using complementary DNA subtraction and microarray analysis in three different species. [Biol Reprod 2005]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:		[R] Adaptor protein CED-6, contains PTB domain

Reagents		tropicalis	laevis a		laevis b
Clones			open biosystems		open biosystems
			geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.11033.1.S1_at [+] Str.5868.1.S1_at	Xl.13266.1.S1_at		Xl.8355.1.S1_at [+] Xl.12195.1.A1_at
Affymetrix 2.0			Xl2.13266.1.S1_a_at		Xl2.8355.1.S1_at [+] Xl2.8355.1.S2_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images