Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (10) GO Terms (34) Nucleotides (120) Proteins (37) Interactants (62) Wiki
Gene Symbol:

Gene Name:
serine/threonine kinase 11

XEEK1 , LKB1 ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine protein kinase

Protein Function :
Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, c...[+]

Loading ...


Disease Ontology:
testicular cancer [+]


External Links:
Xenbase Gene ID XB-GENE-955279 XB-GENE-955285 XB-GENE-17331062
Gene Symbol stk11 stk11.L stk11.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549287
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine stk11 stk11.L stk11.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards STK11 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Stk11 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Stk11 Ensembl
ZFIN, AGR stk11 ZFIN Ensembl
GEISHA STK11 Ensembl
fruit fly
First Cloning and characterization of a novel serine/threonine protein kinase expressed in early Xenopus embryos., J Biol Chem 1996  
Most Recent Proteomics of Primary Cilia by Proximity Labeling., Dev Cell 2015  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 22 terms 10 terms
KEGG Pathways K07298 K07298 K07298
KOG [T] Serine/threonine protein kinase (alt_id KOG:0583)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks stk11
Morpholinos stk11 MO1 stk11 MO1 , stk11 MO2 stk11 MO1 , stk11 MO2
ORFs stk11 ORF1 stk11.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info