Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (120) GO Terms (25) Nucleotides (66) Proteins (35) Interactants (397) Wiki
XB-GENEPAGE-955553
Gene Symbol:
bdnf

Gene Name:
brain-derived neurotrophic factor

Synonyms:
bdnf-a , bdnf-b ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.


InterPro :
Luc7-rel , Sugar P trans dom , Brain-der neurotrophic factor , Nerve growth factor-rel [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
congenital central hypoventilation syndrome [+]

OMIM:
CENTRAL HYPOVENTILATION SYNDROME, CONGENITAL; CCHS [+]

External Links:
 
Xenbase Gene ID XB-GENE-955554 XB-GENE-6252642 XB-GENE-955559
Gene Symbol bdnf bdnf.L bdnf.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100037853
108713815
108715060
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine bdnf bdnf.L bdnf.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BDNF OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Bdnf MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Bdnf Ensembl
zebrafish
ZFIN, AGR bdnf ZFIN Ensembl
chicken
GEISHA BDNF Ensembl
fruit fly
worm
Publications
First Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary., Neuron 1991  
Most Recent Role of TrkA signaling during tadpole tail regeneration and early embryonic development in Xenopus laevis., Genes Cells 2020                  
All View All Papers 8 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 0 term 2 terms
PANTHER bdnf
KEGG Pathways K04355 K04355
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks bdnf
Antibodies Bdnf Ab1 , Bdnf Ab2 Bdnf Ab1 , Bdnf Ab2 Bdnf Ab1 , Bdnf Ab2
Morpholinos bdnf MO1 , bdnf MO2 bdnf MO1 , bdnf MO2 bdnf MO1 , bdnf MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556