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Summary Expression Gene Literature (3) GO Terms (16) Nucleotides (127) Proteins (41) Interactants (494) Wiki
XB-GENEPAGE-955919
Gene Symbol:
stk4

Gene Name:
serine/threonine kinase 4

Synonyms:
krs2 , mst1 , ysk3 ( Add synonyms , Nomenclature history )

Gene Function:
STE20-like serine/threonine kinase MST

Protein Function :
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hipp...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
T-CELL IMMUNODEFICIENCY, RECURRENT INFECTIONS, AND AUTOIMMUNITY WITH OR WITHOUT

External Links:
1/2
 
Xenbase Gene ID XB-GENE-955920 XB-GENE-17342334 XB-GENE-955926
Gene Symbol stk4 stk4.L stk4.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394860
779226
398925
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine stk4 stk4.L stk4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards STK4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Stk4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Stk4 Ensembl
zebrafish
chicken
GEISHA STK4 Ensembl
fruit fly
Publications
First Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors., Int J Dev Biol 2013                        
Most Recent High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Dev Biol 2017                    
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 6 terms 9 terms
PANTHER stk4
KEGG Pathways K04411 K04411 K04411
KOG [T] STE20-like serine/threonine kinase MST
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks stk4
Morpholinos stk4 MO1
ORFs stk4 ORF1 stk4.L ORF1 stk4.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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