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XB-GENEPAGE-955919
Gene Symbol:
stk4
Gene Name: serine/threonine kinase 4
Synonyms:
krs2
,
mst1
,
ysk3
( Gene Function: STE20-like serine/threonine kinase MST Protein Function
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Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hipp...[+]
Interactants:
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Diseases: OMIM:
T-CELL IMMUNODEFICIENCY, RECURRENT INFECTIONS, AND AUTOIMMUNITY WITH OR WITHOUT
External Links:
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Xenbase Gene ID
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XB-GENE-955920 | XB-GENE-17342334 | XB-GENE-955926 | |||||
Gene Symbol | stk4 | stk4.L | stk4.S | Chromosome | Chr10 | chr9_10L | chr9_10S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
394860
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779226
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398925
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | stk4 | stk4.L | stk4.S | |||||
Orthology ![]() |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors., Int J Dev Biol 2013 ![]() |
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Most Recent |
High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Dev Biol 2017 ![]() |
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All | View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 14 terms | 6 terms | 9 terms | |||||
PANTHER | stk4 | |||||||
KEGG Pathways | K04411 | K04411 | K04411 | |||||
KOG |
[T] STE20-like serine/threonine kinase MST
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | stk4 | |||||||
Morpholinos | stk4 MO1 | |||||||
ORFs | stk4 ORF1 | stk4.L ORF1 | stk4.S ORF1 | |||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



