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Summary Expression Gene Literature (11) GO Terms (12) Nucleotides (146) Proteins (37) Interactants (104) Wiki
XB-GENEPAGE-958126
Gene Symbol:
slc30a8

Gene Name:
solute carrier family 30 (zinc transporter), member 8

Synonyms:
znt8 , znt-8 ( Add synonyms , Nomenclature history )

Gene Function:
Zn2+ transporter

Protein Function :
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. Involved in zinc ion homeostasis and cellular distribution.


InterPro :
Cation efflux , Cation efflux CTD sf , ZnT-8 , Cation efflux TMD sf

Interactants:
Loading ...

Diseases: 


Disease Ontology:
type 2 diabetes mellitus

OMIM:
TYPE 2 DIABETES MELLITUS; T2D

External Links:
 
Xenbase Gene ID XB-GENE-958127 XB-GENE-958130 XB-GENE-17334473
Gene Symbol slc30a8 slc30a8.L slc30a8.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496450
496294
108695366
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine slc30a8 slc30a8.L slc30a8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SLC30A8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Slc30a8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Slc30a8 Ensembl
zebrafish
ZFIN, AGR slc30a8 ZFIN Ensembl
chicken
GEISHA SLC30A8 Ensembl
fruit fly
worm
Publications
First Toward an unbiased evolutionary platform for unraveling Xenopus developmental gene networks., Genesis 2012          
Most Recent Differential cytolocation and functional assays of the two major human SLC30A8 (ZnT8) isoforms., J Trace Elem Med Biol 2017  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 6 terms 6 terms
PANTHER slc30a8
KEGG Pathways K14695 K14695 K14695
KOG [P] Zn2+ transporter
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks slc30a8
ORFs slc30a8.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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