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Summary Expression Gene Literature (144) GO Terms (13) Nucleotides (224) Proteins (53) Interactants (553) Wiki
XB-GENEPAGE-958590
Gene Symbol:
pcm1

Gene Name:
pericentriolar material 1

Synonyms:
ptc4 , pcm-1 ( Add synonyms , Nomenclature history )

Gene Function:
Chromatin remodeling complex WSTF-ISWI, large subunit (contains heterochromatin localization, PHD and BROMO domains)

Protein Function :
Required to anchor microtubules to the centrosome. Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including cetn3 and pcnt. Probab...[+]


InterPro :
Pericentriolar Pcm1 , PCM1 C

Interactants:
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Diseases: 


Disease Ontology:
thyroid gland papillary carcinoma

OMIM:
THYROID CANCER, NONMEDULLARY, 1; NMTC1

External Links:
 
Xenbase Gene ID XB-GENE-958591 XB-GENE-958594 XB-GENE-17342393
Gene Symbol pcm1 pcm1.L pcm1.S
Chromosome Chr1 chr1L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100145303
397798
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pcm1 pcm1.L pcm1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PCM1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pcm1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pcm1 Ensembl
zebrafish
ZFIN, AGR pcm1 ZFIN Ensembl
chicken
GEISHA PCM1 Ensembl
fruit fly
worm
Publications
First Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis., J Cell Biol 1999                
Most Recent Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling., Dev Cell 2020    
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 10 terms 0 term
PANTHER pcm1
KEGG Pathways K16537 K16537
KOG [B] Chromatin remodeling complex WSTF-ISWI, large subunit (contains heterochromatin localization, PHD and BROMO domains)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pcm1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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