ung Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (5)

Nucleotides (197)

Interactants (7)

XB-GENEPAGE-960118

[provisional- machine annotated only] Gene Symbol: ung [Predicted: Source is Human Entrez Gene] Gene Name: uracil-DNA glycosylase [Predicted: Source is Human Entrez Gene] Add Xenopus synonyms Gene Function: Uracil DNA glycosylase Interactants: ccno(1) , cenpa(1) , dao(1) , fgf2(1) , h2afx(1) , p2rx7(1) , smug1(1) View All

XB-GENE-960119

XB-GENE-960124

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016580\|Xenopus (Silurana) tropicalis hypothetical protein LOC549334 (LOC549334), mRNA CCATCCCATTTGCCGGCCCAACATGTCAGTAATGTTCTGGCTCCTCCCCTTTCCTAAACTGCCGGTACTCTCTGAAAGTTGGCGCCAAACGAGCGTAGTCTGCAGCATAAGGACTAAACAGCGAATCGGTGCCGGCGTCATAATTCCAGGCTTCTCCAGGGGCGCTATGATCGGCCAGAGAACCATTAACTCGTTTTTCGGGCCTGCAGCAAAGAAAAGAGCTGCACCCGAAGCTTTGGGAGAAGAAGGGCCATACAAGGGAGAGATCACACCTGTGAAAAAGAGCCGTCAGTCCGACGAAAATGAAATCCCCCCTGCCGTGTCTCCGCCCCTCAGCCCCGAGCAGCTGGAGCGCATTCAGAGAAACAAGGCGGCTGCTCTGCAGAAACTAGCGGCGCGGCATGTGCCTGAGGGGCTGGGGCAGAGCTGGAAACAGGCGCTGCTGGCAGAGTTTGCTAAGCCCTACTTTGTTAAGCTATCGAATTTTGTTGCAGAAGAGAGAAAGAAATACACAGTTTATCCACCCCCAGAAGAGGTATTCACCTGGACACAAATGGTTGACATCAAAGATGTGAAGGTTGTCATTTTGGGTCAAGATCCTTATCATGGACCAAATCAAGCACATGGACTTTGCTTTAGCGTTAAGAAACCAGTCCCCCCTCCTCCAAGCTTAGTGAATATGTACAAAGAACTGGAAACTGATATTGAAGGATTTTCACACCCAGGGCATGGTGATCTGACAGGCTGGGCCAAGCAAGGAGTCCTCCTCCTCAATGCTGTACTGACAGTCCGAGCTCATAATGCAAACTCTCACAAGGACTGTGGATGGGAACAGTTCACAGACTCTGTGGTGTCCTGGCTAAACAAAAACATGCATGGTTTGGTTTTCATGTTGTGGGGAGCTTATGCTCAGAAGAAAGGCAGCAATATTGACAGAAAGAGGCACCTTGTTCTCCAAACTGTGCACCCTTCTCCCCTCTCAGCCCACAGAGGCTTTTTTGGCTGTTGTCATTTCTCCAAAACAAATGCCTACCTTCAGGGACTGGAAAAAAAGCCTATTGACTGGAAAGCTCTGTGATGAACATTATGATGTCCTGGAGATGCAAATTCACTTTTTTTGTATGTTTGCCACATTCAGCAAGCACTTATAGTTGTGGGTAATAGTTGACGACTCTTGATTAAACACTAATATGTGATATTTCTCCACATAAATGCTATTTTAAACCACAGCTATTTCATTATTGGCAAAACTTGTGCCTTACCTTGATCTGATCTTTTGTACAGTTTAGTTCAATTACTATTTTACTTACTATGACTTTTGAAATGGTTGTCTTTATAAACTGTGTCTTGATGTTCTTTAATGCATAAGAGAATAACATGTTAGTATTTTCCACCTGGGTTTTGGTTAAGCAGTTAAAAAAAACAAAAAAAACTCTGAAAATATGCAGCTTAGCCAGATTCTGGAAAAAGGGAAAGGACCATGAAAACATTCTGGATGTGTTTTTCAAGTGGTACGGTATCATCTTATGACTCTAGGCTAGCTCCATACAATATAGTTTTTAGGAAATGTTTGTCATATATTTCCAATAGACTTTTTATTTTTGATAATGTAATTTTTGTTTATTATAATGTATGCAAACATTTGAAATGTTAATGAAAGGTGTTTTTATCAGAGTGCATAAATATATTCCTTCTGCATATTTGTTTTGATATGCAAAGATGGAAAATCCTGTAGGTAAGCAAGAGAAAATATACAGAAAGTAAAAGTATTTTGCAGTGCTTTACTTTGTAAAGGATATTAATAGATGAGATCCCCTGCTTTATACATAAGCTTTGTAAGTTTAGGTTTCGGTGAAAATTTATTTCGTTTTTTTCCAAGAGAGTGCCAGCTTTAAGTCAAATTACAATGAGCAACATTTTGCAGACTATAACACTGCTGAATTATCAGTTTTCATTTGTAATTTACCCAAAACAATTGTGAATAGTTGTAAATAAAAAATGTATTTTCCAATATTTGCCTGTAGAAGAATTATTAAAGATGGTAATGTTTACAACATTTTTGTAATAAACCATTTATAAAAAAAAAAAAAAAAAA	Refseq >NM_001091943\|Xenopus laevis uracil-DNA glycosylase (ung), nuclear gene encoding mitochondrial protein, mRNA AAACAGCGAATCGGTGCTGGGATCATTCCAGGCACTTCCCGGGGCACGATGATCGGCCAGAGAACCATTAACTCGTTTTTCGGGGCTGCAGTAAAGAAGAGAGCGGCATCTACGGTGTGGGACGGAGAGGACTCATGCAAGGCGGGAGAGACCACTCCTGTGAAGAAGAGCAGGCCGTCCAATGAGAATGACATCCCCTCAGCCGTGTCTCCTCCCCTCAGCCCCGAGCAGCTGGAGCGCATGCAGAGGAATAAGGCCGCTGCTCTGCAGAAACTCGCAGCCCGCCATGCGCCCCACGGCCTGGGGGAGAGCTGGAAACAGGAGCTGCTGGCTGAGTTTGCAAAACCCTACTTTGTCAAGCTATCAAATTTCATTGCAGAAGAGAGAAAGAAATGCACAGTTTATCCACCACCAGAAGAGGTATTCACCTGGACACAAATGGTTGACATCAAAGATGTAAAGGTTGTTATTTTAGGCCAAGATCCTTATCATGGACCAAATCAAGCTCATGGTCTTTGCTTTAGTGTCAAGAAGCCAGTCCCACCTCCACCCAGCTTAGTGAATATGTACAAAGAACTAGAAACCGATATCGAAGGATTTTCACGCCCAGGTCATGGGGATCTCACAGGCTGGGCCAAACAAGGAGTCCTCCTCCTCAATGCTGTGCTGACAGTGCGAGCTCATAATGCAAACTCTCACAAGGACTGTGGATGGGAACAGTTCACAGATGTTGTGGTATCCTGGCTAAATAAGAACATGGATGGGTTGGTTTTCATGCTGTGGGGAGCCTATGCCCAGAAGAAAGGCAGCAATATTGACAGAAAAAGGCACCATGTTCTTCAAACCGTGCACCCTTCTCCTCTCTCAGTCCACAGAGGCTTTTTTGGCTGTCGTCATTTCTCCAAAACGAATGCCTACCTCCAGGGACTGGGAAAAAAGCCTATTGACTGGAAAGCTCTGTGACAAATTGCCTTTTCCCCCATTAGTTGGCCACATTTGGCAAGCACTTATAGTTGTGGGCAATAGTTGACTACTCTTGATTAAACACTAAGTGATATTTCTTCATGTAAAAGCCCTTTTAAACCACAACTATTTCAGTATTGGCAAAACTAGTGCCTTACTTAGAACTGAGTTGGTGTCGTTTCTGTGAAAATGATTGTTTTGTACTATGGAACAACTGTAGATGTCTCTTGTTTTAATGGCATAATACCATCTTATAGCACTAGGCTAGCTCCATGCCATTTAGACAATCTATAACCATTGGTTTTCAAGTGTGTGTATATAGTTGTAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016580\|uracil-DNA glycosylase [Xenopus (Silurana) tropicalis] MIGQRTINSFFGPAAKKRAAPEALGEEGPYKGEITPVKKSRQSDENEIPPAVSPPLSPEQLERIQRNKAAALQKLAARHVPEGLGQSWKQALLAEFAKPYFVKLSNFVAEERKKYTVYPPPEEVFTWTQMVDIKDVKVVILGQDPYHGPNQAHGLCFSVKKPVPPPPSLVNMYKELETDIEGFSHPGHGDLTGWAKQGVLLLNAVLTVRAHNANSHKDCGWEQFTDSVVSWLNKNMHGLVFMLWGAYAQKKGSNIDRKRHLVLQTVHPSPLSAHRGFFGCCHFSKTNAYLQGLEKKPIDWKAL	Refseq >NP_001085412\|uracil-DNA glycosylase [Xenopus laevis] MIGQRTINSFFGAAVKKRAASTVWDGEDSCKAGETTPVKKSRPSNENDIPSAVSPPLSPEQLERMQRNKAAALQKLAARHAPHGLGESWKQELLAEFAKPYFVKLSNFIAEERKKCTVYPPPEEVFTWTQMVDIKDVKVVILGQDPYHGPNQAHGLCFSVKKPVPPPPSLVNMYKELETDIEGFSRPGHGDLTGWAKQGVLLLNAVLTVRAHNANSHKDCGWEQFTDVVVSWLNKNMDGLVFMLWGAYAQKKGSNIDRKRHHVLQTVHPSPLSVHRGFFGCRHFSKTNAYLQGLGKKPIDWKAL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.7397 [+] Str.45183	Xl.6649
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	UNG	OMIM:608106
mouse		MGI	Ung	All(3) Targeted, knock Out(2) Targeted, other(1)
zebrafish		ZFIN	unga

Publications
First:		Characterization of the mutX gene of Streptococcus pneumoniae as a homologue of Escherichia coli mutT, and tentative definition of a catalytic domain of the dGTP pyrophosphohydrolases. [Mol Microbiol 1994]
Most recent:		Enzymatic excision of uracil residues in nucleosomes depends on the local DNA structure and dynamics. [Biochemistry 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		DNA N-glycosylase activity hydrolase activity, hydrolyzing N-glycosyl compounds single-strand selective uracil DNA N-glycosylase activity More[+] uracil DNA N-glycosylase activity
Biological:		DNA repair
Cellular Component:
EC:		Hydrolysing N-Glycosyl Compounds
KOG:		[L] Uracil DNA glycosylase

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.7397.1.S2_at [+] Str.45183.1.A1_at Str.7397.1.S1_at	Xl.6649.1.S1_at
Affymetrix 2.0			Xl2.6649.1.S1_at

Symbol legend[+]