abcc1 Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-960170

[provisional- machine annotated only]

Gene Symbol: abcc1 [Predicted: Source is Human Entrez Gene]

Gene Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Predicted: Source is Human Entrez Gene]

Synonyms: mrp, abcc, gs-x, mrp1, abc29 Add Xenopus synonyms

Gene Function: Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily

Interactants: wls(17) , abcc2(4) , kcnj11(2) , znf143(2) , abca8(1) , abcc8(1) , abcc9(1) View All

XB-GENE-960171

XB-GENE-6488750

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene
mRNA	Refseq >NM_001127001\|Xenopus (Silurana) tropicalis ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (abcc1), mRNA AGTTTGTGGTTCTGTTTGTGTCTCCCGGAGGTGTCCCCGGCTGCCATCATCAGTGTCCCTTGTGCTGCCCGGCATGGAATCCTTCTGCAGCTATGACGGCAGCGAGCGCTTTTGGGATTCTAATCTCACCTGGTATACAGAAAATCCAGATTTCACCAAGTGCTTCCAAAATACAGTCCTGATATGGATTCCATGCATCTACCTCTGGTTCTGCTTACCGTTCTACTTTGTATACCTCCGGAAAAATGACCAAGGCTACATCCAAATGTCACACCTCAACAAGGCCAAAACAGCTATAGGTTTCATCTTATGGCTTGCCTGCTGGGCAGATCTCTTTTATTCATTCTGGGAAAGGAGCCAGAGTATTTATCGTGCTCCAGTATATGTTGTGAGCCCAACTGTACTTGGTATAACAATGCTGCTAGCTACTTTTTTAATCCAGTATGAAAGAATTAAAGGAGTACAGTCTTCAGGTGTAATGTTGAATTTCTGGATCGTTGCGTTGTTGTGTGCCATAATAATCTTCAGGTCCAAAGTTCTACATGCCTTAAAACCGGATGCTCAGATAGATGTCTTTCGGGACACCACATTCTATATATACTTTTTGCTGGTGTTGGTGGAGCTTATTCTTTCAGCCTTTCCAGACCGGCCACCTCTGTTTTCTGAAAGAGTCAATGACCCTAACCCTTGTCCAGAGTCAAGTGCATCCTTCCTTTCCCAGATCACTTTTTGGTGGATAAGTAGGATGATGGTTCAGGGATTTAAGCGGCCATTGGAAGCTAAAGATTTATGGTCCTTAAACAAAGAAGACAAATCATTGGAAGTTGTACCTGTCCTATCCAAGAATTGGGAAAAGGAATACAACAAAGCCAAAGCCAAAAAGGTCCCATTGAAAATGGTGTACTCACCCAAAAAGCAAACCAAGAAACTAAACTCAAAGGAGGACGTCAGAGAGGAGGCAGAGGCTCTCATTGTTAAACCAGCCCCCATGGTTTTAAATTAAATATCCATGTTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein	Refseq >NP_001120473\|ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Xenopus (Silurana) tropicalis] MESFCSYDGSERFWDSNLTWYTENPDFTKCFQNTVLIWIPCIYLWFCLPFYFVYLRKNDQGYIQMSHLNKAKTAIGFILWLACWADLFYSFWERSQSIYRAPVYVVSPTVLGITMLLATFLIQYERIKGVQSSGVMLNFWIVALLCAIIIFRSKVLHALKPDAQIDVFRDTTFYIYFLLVLVELILSAFPDRPPLFSERVNDPNPCPESSASFLSQITFWWISRMMVQGFKRPLEAKDLWSLNKEDKSLEVVPVLSKNWEKEYNKAKAKKVPLKMVYSPKKQTKKLNSKEDVREEAEALIVKPAPMVLN

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.36571	Xl.73750 [+] Xl.14807
Unigene EST Profile	EST Profile	EST Profile
GEO data		GEO
Images	0 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	ABCC1
mouse	MGI	Abcc1	All(5) Targeted, knock Out(3) Targeted, other(2)
zebrafish		abcc1

Publications
First:		Characterization of a Xenopus laevis ribonucleoprotein endoribonuclease. Isolation of the RNA component and its expression during development. [J Biol Chem 1992]
Most recent:		Arsenate transport by sodium/phosphate cotransporter type IIb. [Toxicol Appl Pharmacol 2010]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding ATPase activity ATPase activity, coupled to transmembrane movement of substances More[+] nucleoside-triphosphatase activity nucleotide binding protein kinase activity transporter activity
Biological:		protein amino acid phosphorylation transport
Cellular Component:		integral to membrane
EC:
KOG:		[Q] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily

Reagents	tropicalis	laevis
Clones	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.36571.1.S1_at	Xl.19251.1.S1_at
Affymetrix 2.0		Xl2.19251.2.S1_at [+] Xl2.51327.1.S1_at Xl2.19251.1.A1_at Xl2.14807.1.A1_at

Symbol legend[+]