Gene Symbol: gnrh1 Gene Name: gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) Synonyms: gnrh, grh, lhrh, lnrh, progonadoliberin-1, luliberin i, luteinizing hormone Add Xenopus synonyms Gene Function: hormone Interactants: gnrhr(9) , arrb2(5) , arrb1(4) , mapk1(4) , prl.2(4) , avp(3) , prl.1(3) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene
mRNA		Refseq >NM_001113693|Xenopus (Silurana) tropicalis gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) (gnrh1), mRNA GATGAAGGCCATTTCCACCTATGCTCTTCTGCTCCTTGTCCTTCTATTTTCTGCCCACGTTGGTCATGCCCAGCATTGGTCCTATGGTCTCCGGCCAGGAGGGAAGAGGGACGCTGAAAGTCTCCAGGACATGTACCCTGAGACTCCAAATGAGGTTCCTTTGTTTCCGGAACTCGAGCGCTTGGAGTGTTCTGTCCCCCAGAGCCGACTCAACGTACTGAGAGGAGCACTGATGAGCTGGCTGGATGGAGAGAACAGAAAGAAGATCTGATACTGGCAGCACCATGAGACGAGGAGGATGATCCAATAAATATAGATTAAGGCTACACTT	NCBI Nucleotide >L28040|Xenopus laevis polyprotein encoding gonadotropin-releasing hormone-I (GnRH-I) and GnRH associated peptide (GAP) mRNA, complete cds CAGATACAGGAGCTGGAGCCAGAAGCACTGGGCATAACCACATACAGACAGCAGGATGAAAGCCTTTCCCACCTTTGCTCTTCTGTTCCTGGTCCTCCTGTTTTCTGCCCACGTTAGTGATGCCCAGCACTGGTCCTATGGTCTCCGGCCTGGAGGGAAGAGGGACACTGAAAGTCTCCAGGACATGTACCATGAGACACCCAATGAGGTTGCCTTGTTCCCGGAACTCGAGCGTCTGGAATGTTCCGTCCCCCAAAGCAGACTCAACGTACTGAGAGGAGCGCTGATGAACTGGCTGGAAGGAGAGAACAGAAAGAAGATCTGATAATGGCAGAGCCACAAGAGGAAGATGATTAAATAAATGCAGACTAAAGCGAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001107165|gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) precursor [Xenopus (Silurana) tropicalis] MKAISTYALLLLVLLFSAHVGHAQHWSYGLRPGGKRDAESLQDMYPETPNEVPLFPELERLECSVPQSRLNVLRGALMSWLDGENRKKI	NCBI Protein >AAA49728|luteinizing-releasing hormone [Xenopus laevis] MKAFPTFALLFLVLLFSAHVSDAQHWSYGLRPGGKRDTESLQDMYHETPNEVALFPELERLECSVPQSRLNVLRGALMNWLEGENRKKI UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.77407
Unigene EST Profile		EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	GNRH1
mouse		MGI	Gnrh1	All(4) Spontaneous(1) Targeted, other(1)
zebrafish

Publications
First:		Determination of the distribution of luteinizing hormone-like gonadotrophic activity within the dogfish pituitary gland by means of the Xenopus oocyte meiosis assay. [J Endocrinol 1973]
Most recent:		Aqueous leaf extracts display endocrine activities in vitro and disrupt sexual differentiation of male Xenopus laevis tadpoles in vivo. [Gen Comp Endocrinol 2013]
		View All Papers

Functional Ontologies
GO: Molecular:		hormone activity luteinizing hormone-releasing factor activity
Biological:		multicellular organismal development
Cellular Component:		extracellular region
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		StrEns.1069.1.S1_at
Affymetrix 2.0

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