Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (21) Nucleotides (220) Proteins (51) Interactants (404) Wiki
XB-GENEPAGE-960930
Gene Symbol:
cul2

Gene Name:
cullin 2

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
E3 ubiquitin ligase component

Protein Function :
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-960931 XB-GENE-960935 XB-GENE-17339987
Gene Symbol cul2 cul2.L cul2.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100492608
379729
108719839
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cul2 cul2.L cul2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CUL2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cul2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cul2 Ensembl
zebrafish
ZFIN, AGR cul2 ZFIN Ensembl
chicken
GEISHA CUL2 Ensembl
fruit fly
FLYBASE Cul2 Ensembl
worm
Publications
First A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway., Mol Neurodegener 2017    
Most Recent TRAIP is a master regulator of DNA interstrand crosslink repair., Nature 2019                            
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 4 terms 4 terms
PANTHER cul2
KEGG Pathways K07917 [+] K03870 K03870
KOG [O] E3 ubiquitin ligase, Cullin 2 component
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cul2
ORFs cul2.L ORF1
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.16.0
Major funding for Xenbase is provided by grant P41 HD064556