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Summary Expression Gene Literature (9) GO Terms (27) Nucleotides (89) Proteins (43) Interactants (136) Wiki
XB-GENEPAGE-961763
Gene Symbol:
pak3

Gene Name:
p21 protein (Cdc42/Rac)-activated kinase 3

Synonyms:
XPak3 , bpak , mrx30 , mrx47 , ophn3 , cdkn1a , pak3beta ( Add synonyms , Nomenclature history )

Gene Function:
p21-activated serine/threonine protein kinase

Protein Function :
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways. Involved in early neuronal development; required for cell cycle exit and differentiation of primary neuro...[+]



Interactants:
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Diseases: 


Disease Ontology:
non-syndromic X-linked intellectual disability [+]

OMIM:
MENTAL RETARDATION, X-LINKED 30; MRX30

External Links:
 
Xenbase Gene ID XB-GENE-961764 XB-GENE-961767 XB-GENE-17330501
Gene Symbol pak3 pak3.L pak3.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100495025
378493
108700104
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pak3 pak3.L pak3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PAK3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pak3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pak3 Ensembl
zebrafish
chicken
GEISHA PAK3 Ensembl
fruit fly
FLYBASE Pak3 Ensembl
Publications
First XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis., EMBO J 2002  
Most Recent The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis., Sci Rep 2018                        
All View All Papers 6 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 14 terms 5 terms
PANTHER pak3
KEGG Pathways K05733 K05733 K05733
KOG [T] p21-activated serine/threonine protein kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pak3
Antibodies Pak1 Pak2 Pak3 Ab3 Pak1 Pak2 Pak3 Ab3
Morpholinos pak3 MO1 pak3 MO1 pak3 MO1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info