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Summary Expression Gene Literature (9) GO Terms (9) Nucleotides (79) Proteins (35) Interactants (45) Wiki
XB-GENEPAGE-962825
Gene Symbol:
orai1

Gene Name:
ORAI calcium release-activated calcium modulator 1

Synonyms:
tmem142a ( Add synonyms , Nomenclature history )

Gene Function:
CAP-binding protein complex interacting protein 2

Protein Function :
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim1.


InterPro :
CRAC channel , Orai sf , Orai-2 , TPR-like helical dom sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Stormorken syndrome [+]

OMIM:
IMMUNODEFICIENCY 9; IMD9 [+]

External Links:
 
Xenbase Gene ID XB-GENE-962826 XB-GENE-17345572 XB-GENE-962830
Gene Symbol orai1 orai1.L orai1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100125061
108707681
403390
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine orai1 orai1.L orai1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ORAI1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Orai1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Orai1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR orai1b orai1a ZFIN Ensembl
chicken
GEISHA ORAI1 Ensembl
fruit fly
worm
Publications
First Spontaneous calcium spike activity in embryonic spinal neurons is regulated by developmental expression of the Na+, K+-ATPase beta3 subunit., J Neurosci 2009  
Most Recent The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis., Sci Rep 2021                  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 1 terms 1 terms
PANTHER orai1
KEGG Pathways K16057 K16057 K16057
KOG [A] CAP-binding protein complex interacting protein 2
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks orai1
ORFs orai1 ORF1 orai1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info