Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (157) GO Terms (12) Nucleotides (597) Proteins (54) Interactants (1168) Wiki
XB-GENEPAGE-966993
Gene Symbol:
gmnn

Gene Name:
geminin, DNA replication inhibitor

Synonyms:
geminin , gem ( Add synonyms , Nomenclature history )

Gene Function:
negative regulation of DNA replication

Protein Function :


InterPro :
Kinesin motor dom , Kinesin motor dom sf , P-loop NTPase , Kinesin motor CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Meier-Gorlin syndrome

OMIM:
MEIER-GORLIN SYNDROME 6; MGORS6

External Links:
1/4
 
Xenbase Gene ID XB-GENE-966994 XB-GENE-17335446 XB-GENE-967001
Gene Symbol gmnn gmnn.L gmnn.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496859
398096
399373
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gmnn gmnn.L gmnn.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GMNN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gmnn MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gmnn Ensembl
zebrafish
ZFIN, AGR gmnn ZFIN Ensembl
chicken
GEISHA GMNN Ensembl
fruit fly
worm
Publications
First Geminin, an inhibitor of DNA replication, is degraded during mitosis., Cell 1998  
Most Recent Ongoing replication forks delay the nuclear envelope breakdown upon mitotic entry., J Biol Chem 2020                    
All View All Papers 9 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 3 terms 3 terms
PANTHER gmnn
KEGG Pathways K10749 K10749 K10749
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gmnn
Morpholinos (on-target & off-target) gmnn MO1 gmnn MO1 , gmnn MO2 gmnn MO1
ORFs gmnn ORF1 gmnn.L ORF1 gmnn.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info