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Summary Expression Gene Literature (141) GO Terms (7) Nucleotides (579) Proteins (39) Interactants (1028) Wiki
XB-GENEPAGE- 966993

Gene Symbol: gmnn

Gene Name: geminin, DNA replication inhibitor

Synonyms: geminin , gem
Add Xenopus synonyms , Nomenclature history


Gene Function: negative regulation of DNA replication

Protein Function :


Interactants: Loading ...

Disease Ontology Associations:

OMIM Disease Associations: GEMININ; GMNN
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Xenbase Gene ID XB-GENE-966994 XB-GENE-17335446 XB-GENE-967001
Gene Symbol gmnn gmnn.L gmnn.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.6403 [+] Xl.461
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 48 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gmnn gmnn.L gmnn.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GMNN OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Gmnn MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR gmnn ZFIN Ensembl
chicken
GEISHA GMNN Ensembl
fruit fly
worm
WORMBASE
Publications
First: Geminin, an inhibitor of DNA replication, is degraded during mitosis. [Cell 1998]
Most recent: Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei. [Genes Cells 2018]
View All Papers 9 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontologies
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 2 terms 2 terms
PANTHER gmnn
KEGG Pathways K10749 K10749 K10749
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino gmnn MO1 , gmnn MO2 gmnn MO1 , gmnn MO2 gmnn MO1 , gmnn MO2
ORF LOC398096 ORF1 gmnn ORF1
Affymetrix 1.0 Str.6403.1.S1_at [+] Xl.462.1.S1_at Xl.461.1.S1_at
Affymetrix 2.0 Xl2.462.1.S1_at Xl2.461.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556