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Summary Expression Gene Literature (4) GO Terms (37) Nucleotides (213) Proteins (50) Interactants (191) Wiki
Gene Symbol:

Gene Name:
CASC3, exon junction complex subunit

mln51 , btz , barentsz ( Add synonyms , Nomenclature history )

Gene Function:
nucleo-cytoplasmic protein

Protein Function :
Required for pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dy...[+]

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External Links:
Xenbase Gene ID XB-GENE-969211 XB-GENE-17335605 XB-GENE-969217
Gene Symbol casc3 casc3.L casc3.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 503560
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine casc3 casc3.L casc3.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards CASC3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Casc3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Casc3 Ensembl
ZFIN, AGR casc3 ZFIN Ensembl
fruit fly
First Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module., J Biol Chem 2004  
Most Recent In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles., Toxicol Sci 2015  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 37 terms 12 terms 11 terms
KEGG Pathways K00940 [+] K14323 K14323
KOG [R] Nucleo-cytoplasmic protein MLN51
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks casc3
ORFs casc3.L ORF1 rpl13.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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