eef2.1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (3)

Nucleotides (5136)

Interactants (2)

XB-GENEPAGE-969738

[provisional- machine annotated only] Gene Symbol: eef2.1 [Predicted: Source is Human Entrez Gene] Gene Name: eukaryotic translation elongation factor 2, gene 1 [Predicted: Source is Human Entrez Gene] Synonyms: ef2, eef-2 Add Xenopus synonyms Gene Function: Elongation factor 2 Interactants: eef2.2(3) , ahcy(1) , View All

XB-GENE-969739

XB-GENE-969746

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_203924\|Xenopus (Silurana) tropicalis eukaryotic translation elongation factor 2, gene 1 (eef2.1), mRNA CCGCCATTGCCCCTATATATTGCGAACCGTTGACGTCAGCGGTCTCTTCCGCCTGTTTGTCTGCTGTGAGGCAGACTGTCCGTATCGGCCTAAGCCCGTCCCGTGAAGAGAATCCACCGCCATCTGCCACAATGGTGAACTTCACGGTAGACCAGATTCGTTCCATCATGGACAAGAAGGCGAACATTCGTAATATGTCGGTCATTGCCCATGTGGACCACGGTAAATCTACTCTGACTGACTCACTGGTATGCAAGGCTGGTATCATTGCTTCTGCTAGGGCTGGTGAGACTCGTTTTACAGATACCAGAAAAGATGAACAAGAGAGATGTATCACCATCAAATCAACAGCAATCTCTCTCTTCTATGAGCTCTCTGAGAACGATTTGGCTTTTATCAAGCAAAGCAAAGATGGGTGTGGCTTCCTTATAAACTTGATTGACTCCCCTGGCCATGTAGACTTTTCCTCTGAAGTAACTGCTGCTCTTCGTGTCACAGATGGTGCCTTAGTTGTAGTGGACTGTGTTTCAGGCGTCTGTGTGCAGACTGAAACCGTGCTTCGTCAAGCCATTGCAGAGCGCATCCGCCCTGTGTTGATGATGAACAAAATGGATCGTGCTCTTTTGGAGCTGCAGTTGGAACCAGAGGAGCTCTACCAAACTTTTCAGCGCATTGTGGAGAATGTTAATGTGATTATTTCCACCTACGGTGAAGGAGAGACTGGACCCATGGGAAATATCATGATTGACCCTGTTCTTGGCACAGTTGGTTTTGGCTCTGGTCTGCATGGCTGGGCTTTCACACTAAAACAGTTTGCAGAGATGTATGTCGCAAAATTTGCAGCAAAGGGGGAAGGTCAGTTGGCTCCTGCAGAACGGGCCAAAAAAGTGGAGGACATGATGAAGAAGCTGTGGGGTGATAGGTATTTTGACCCTGCAAATGGAAAGTTCAGCAAGTCTGCAACAAACGCTGATGGCAAAAAACTTCCTAGAACCTTCTGCCAGCTTGTATTGGATCCAATTTTCAAGGTATTTGATGCAATCATGAATTTTAAGAAAGAAGAAACTGCCAAATTGGTCGAGAAACTAGACATCAAACTTGACAGTGAGGACAAAGACAAAGAGGGAAAACAGTTGCTTAAGGCTGTTATGAGACGCTGGCTCCCAGCTGGAGAGGCTCTTCTGCAGATGATTACCATCCACTTGCCCTCACCAGTGACTGCTCAGAAATACCGTTGTGAGCTGTTGTATGAGGGTCCCCCAGATGATGAAGCTGCCATGGGTATCAAGAACTGTGACCCCAAAGGCCCTCTTATGATGTACATCTCAAAAATGGTGCCCACCACTGACAAGGGTAGATTTTATGCCTTTGGAAGAGTTTTCTCAGGTGTAGTCTCCACTGGCCTCAAAGTCAGGATAATGGGACCAAACTTCACTCCAGGCAAGAAGGAGGACCTTTACCTAAAACCCATTCAGAGGACCATTCTGATGATGGGAAGATATGTGGAACCCATTGAGGATGTGCCATGTGGAAACATTGTTGGTTTAGTTGGAGTAGATCAGTTCCTGGTTAAGACTGGAACAATCACTACCTTTGAACATTCACATAACATGCGTGTTATGAAGTTTAGTGTCAGCCCTGTTGTGCGTGTTGCTGTGGAAGCAAAGAATCCTGCTGATCTCCCTAAGTTGGTTGAGGGTCTGAAACGTCTAGCTAAATCAGACCCCATGGTTCAGTGCATCATTGAAGAATCTGGCGAGCATATCATTGCTGGAGCTGGGGAGCTGCATTTGGAGATTTGCCTGAAGGATCTTGAGGAGGATCATGCCTGCATTCCAATAAAGAAATCTGATCCAGTCGTATCTTACCGTGAGACTGTGAGCGAGGAGTCCAACCAGATGTGCCTGTCAAAGTCTCCTAACAAGCACAACCGTCTGTTTATGAAGTGTCGACCTTTTCCTGATGGTCTTGCTGAAGACATTGATAAAGGTGATGTATCTGCTCGCCAGGAGTTGAAGACTCGTGCCCGCTACTTGGCTGAAAAGTACGAATGGGATGTGACTGAAGCTAGGAAGATTTGGTGTTTTGGTCCTGATGGCTCTGGGCCCAACATACTTACTGATGTTACTAAGGGAGTTCAGTATCTGAATGAAATCAAAGACAGCGTTGTTGCAGGATTCCAGTGGGCTACAAAGGAGGGTGTCCTGTGTGAAGAAAATTTGAGAGGTGTTCGTTTTGATGTCCATGATGTAACACTTCATGCTGATGCCATCCATAGAGGAGGAGGACAGATCATTCCAACTGCACGCCGCGTCTTGTATGCTTGTGTGTTGACTGCTCAGCCACGTCTGATGGAACCAATCTACCTTGTTGAAATTCAGTGCCCTGAGCAGGTGGTAGGAGGTATCTATGGTGTCTTGAACAGAAAGCGTGGGCATGTCTTTGAAGAATCCCAGGTGGCTGGAACACCAATGTTTGTGGTTAAGGCATACCTGCCTGTAAATGAGTCATTTGGTTTCACTGCTGACTTAAGATCAAACACTGGTGGCCAGGCCTTCCCTCAGTGTGTGTTTGACCACTGGCAAATTCTACCTGGAGATCCTTTCGATAACACCACCAGGCCTTTCCAAGTGGTGGCAGAGACCCGGAAGAGGAAGGGCTTGAAAGAGGGTGTTCAAGCCTTGGATAACTTCCTTGACAAGCTGTAAACCTTTGCTTTACTCCTGTCAGCATTGATTAAGTGGAAATGAACTATACCCAAAAGATGTCAGCATTCCCTGCAACATTCTGTTGGAACCCTGAATATAATCTTTCATTGGCATGATCATAACTTTCTATTTATTCTTGATGGGTAGCTTCTGCTCTCTGAAAACATCTTGGATGGCTGGGGAAGTAAATGTGAATTTGAGGGTTGACAGGAACGAGGGCAGAATGTAGAGCAAAGATGTACTGCAATAACCTTGAATGACTTATTGGTGCCATTAAAAAAATTTAATTGAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001087187\|Xenopus laevis eukaryotic translation elongation factor 2, gene 1 (eef2.1), mRNA GGCAGACTGTTTGCATCGTCCTAAGCCAGTCCCGTGAAGAGAATCCATCGCCATCTGCCACAATGGTGAACTTCACGGTAGACCAGATTCGTTCCATCATGGACAAGAAGGCGAACATTCGTAATATGTCGGTCATTGCCCATGTGGACCACGGCAAATCTACTCTGACTGACTCACTCGTGTGCAAGGCCGGTATTATTGCCTCTGCCAGGGCTGGCGAGACCCGTTTTACTGACACCAGAAAAGATGAACAGGAGAGATGCATCACCATCAAATCAACAGCAATCTCTCTATTCTACGAGCTGTCTGAGAATGACTTGGCTTTTATCAAGCAAAGCAAAGATGGTTGTGGCTTTCTTATAAACTTGATTGACTCCCCTGGCCATGTGGACTTTTCCTCTGAAGTGACTGCTGCTCTTCGTGTCACAGATGGTGCCTTAGTTGTAGTGGACTGTGTTTCTGGCGTCTGTGTGCAGACTGAAACAGTGCTTCGTCAAGCCATTGCTGAGCGTATCCGCCCTGTATTGATGATGAATAAGATGGATCGTGCTCTTTTAGAGCTGCAGCTGGAACCAGAGGCGCTCTATCAAACTTTTCAGCGCATTGTTGAGAATGTCAATGTGATTATTTCCACCTATGGTGAAGGGGAGAGTGGACCCATGGGAAATATCATGATTGACCCTGTTCTTGGCACAGTTGGTTTTGGCTCTGGTCTGCATGGCTGGGCTTTCACACTAAAACAGTTTGCAGAGATGTATGTTGCAAAATTTGCAGCAAAGGGTGAAGGCCAATTAGCTCCATCAGAACGGTGCAAAAAAGTGGAGGACATGATGAAGAAGCTGTGGGGGGATAGGTATTTTGACCCTTCAAATGGAAAGTTCAGCAAATCTGCAGTAAATGCTGATGGCAAAAAACTTCCTAGAACCTTCTGCCAACTTATATTGGATCCAATTTTTAAGGTATTTGATGCAATCATGAATTTCAAGAAAGAAGAAACTGCCAAACTGATTGAGAAGCTAGACATCAAACTTGACAGTGAGGATAAGGACAAAGAGGGAAAGCAATTGCTTAAGTCTGTTATGAGACGCTGGCTCCCAGCTGGAGAGGCTCTTCTGCAGATGATTACCATCCACTTGCCCTCACCAGTGACTGCTCAGAAATACCGTTGTGAATTGTTGTATGAGGGTCCCCCAGATGATGAAGCTGCCATGGGAGTCAAGAACTGTGACCCTAAAGGCCCTCTAATGATGTACATCTCAAAAATGGTGCCCACCACTGACAAAGGTAGATTTTATGCCTTTGGAAGAGTTTTCTCAGGTGTCGTCTCCACTGGCCTTAAAGTCCGGATTATGGGACCAAACTTCACTCCAGGCAAAAAGGAGGACCTTTACATAAAACCCATTCAGAGGACCATTCTGATGATGGGACGATATGTGGAACCCATTGAGGATGTGCCATGTGGAAACATTGTTGGTTTAGTTGGAGTAGATCAGTACCTGGTTAAGACCGGAACAATCTCTACTTTTGAACATGCACACAACATGCGTGTTATGAAGTTTAGTGTCAGCCCTGTTGTGAGAGTTGCTGTGGAAGCAAAGAATCCTGCTGATCTCCCCAAGTTGGTTGAGGGTCTGAAACGTCTAGCTAAATCAGACCCCATGGTGCAGTGCATCATCGAAGAATCTGGCGAGCATATCATTGCAGGAGCTGGAGAGCTGCACTTGGAGATTTGCCTGAAGGATCTTGAGGAAGATCATGCCTGCATTCCAATAAAGAAATCTGACCCAGTTGTATCTTACCGTGAGACTGTGAGTGAAGAGTCCAGCCAGATGTGCCTGTCAAAGTCTCCTAACAAGCACAACCGTCTGTTTATGAAGGCTCGACCTTTCCCTGACGGTCTTGCAGAAGACATTGATAAAGGTGATGTGTCTGCTCGTCAGGAGTTGAAGACTCGTGCACGCTACTTGGCTGAAAAGTATGAATGGGATGTAACTGAAGCTAGGAAGATTTGGTGCTTTGGTCCTGATGGCTCTGGGCCCAACATACTTACTGATGTTACTAAGGGAGTTCAGTATCTGAATGAAATAAAAGACAGTGTTGTTGCAGGATTTCAGTGGGCTACAAAGGAGGGTGTCTTGTGTGAAGAAAATCTGAGAGGTGTTCGTTTTGATGTTCATGATGTAACTCTTCATGCTGATGCCATTCATAGAGGAGGAGGACAGATCATTCCAACTGCACGCAGAGTCTTGTATGCTTGTGTGTTGACTGCTCAACCACGTTTGATGGAACCAATCTATCTTGTTGAAATTCAGTGCCCTGAGCAAGTGGTGGGAGGAATCTATGGTGTATTGAACAGAAAGCGTGGGCATGTCTTTGAAGAATCCCAGGTGGCTGGAACACCAATGTTTGTTGTTAAGGCTTACCTGCCTGTAAATGAGTCATTTGGTTTCACTGCTGACTTAAGATCAAATACTGGTGGCCAGGCCTTCCCTCAGTGTGTATTTGACCATTGGCAAATTCTGCCTGGCGATCCTTTCGATAACACCACCCGGCCTTCCCAAGTAGTTGCAGAGACCCGGAAGAGGAAGGGCTTGAAAGAGGGTGTTTCAGCCTTGGATAACTTCCTTGACAAGCTGTAAACCTTTATTGCTTTACTCCTGTCAGCAGAATTGATTAGGTGAAATGAACTTTACCCTAAGATGTCAGCATTCCCTGCAACATTCTGTTGGAACCCTGAATATGAATCTCATTGGCATGATCATACCTTTCTATTTATTCTGGATGGGTAGCTTCTGCCCTCTGAACACATCCTGGATTGCTGGCAAAGTAAATGTGGAGAGTTGACAGGAACTGGGGCAGAATGTAGAGCAAAGATGTAATGCAATTAAAGCATGAATGACTTAATGGTGCCATTAAACAATTTAATCTGAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_989255\|eukaryotic translation elongation factor 2, gene 1 [Xenopus (Silurana) tropicalis] MVNFTVDQIRSIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLAFIKQSKDGCGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIRPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGETGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLAPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATNADGKKLPRTFCQLVLDPIFKVFDAIMNFKKEETAKLVEKLDIKLDSEDKDKEGKQLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNFTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHSHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNQMCLSKSPNKHNRLFMKCRPFPDGLAEDIDKGDVSARQELKTRARYLAEKYEWDVTEARKIWCFGPDGSGPNILTDVTKGVQYLNEIKDSVVAGFQWATKEGVLCEENLRGVRFDVHDVTLHADAIHRGGGQIIPTARRVLYACVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNTTRPFQVVAETRKRKGLKEGVQALDNFLDKL	Refseq >NP_001080656\|eukaryotic translation elongation factor 2, gene 1 [Xenopus laevis] MVNFTVDQIRSIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLAFIKQSKDGCGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIRPVLMMNKMDRALLELQLEPEALYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLAPSERCKKVEDMMKKLWGDRYFDPSNGKFSKSAVNADGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKQLLKSVMRRWLPAGEALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGVKNCDPKGPLMMYISKMVPTTDKGRFYAFGRVFSGVVSTGLKVRIMGPNFTPGKKEDLYIKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQYLVKTGTISTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESSQMCLSKSPNKHNRLFMKARPFPDGLAEDIDKGDVSARQELKTRARYLAEKYEWDVTEARKIWCFGPDGSGPNILTDVTKGVQYLNEIKDSVVAGFQWATKEGVLCEENLRGVRFDVHDVTLHADAIHRGGGQIIPTARRVLYACVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNTTRPSQVVAETRKRKGLKEGVSALDNFLDKL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.47001 [+] Str.32162 Str.28919 Str.44660 Str.58699	[+] Xl.19822 Xl.84251 Xl.84576 Xl.85673
Unigene EST Profile		EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	EEF2
mouse		MGI	Eef2	All(2) Targeted, knock Out(1)
zebrafish		ZFIN ZFIN	eef2 eef2b

Publications
First:		Downregulation of the translation elongation factor 2 kinase in Xenopus laevis oocytes at the final stages of oogenesis. [New Biol 1990]
Most recent:		Proteomic screen for potential regulators of M-phase entry and quality of meiotic resumption in Xenopus laevis oocytes. [J Proteomics 2010]
		View All Papers

Functional Ontologies
GO: Molecular:		GTP binding GTPase activity protein-synthesizing GTPase activity
Biological:		translation
Cellular Component:
EC:		protein-synthesizing GTPase
KOG:		[J] Elongation factor 2

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.6697.1.S1_at [+] Str.22303.1.S1_at Str.41412.2.A1_x_at Str.43558.1.A1_at Str.13030.1.A1_at Str.44660.1.A1_at Str.47001.1.A1_at	Xl.7551.1.S1_x_at [+] Xl.7551.2.S1_x_at Xl.7551.2.S1_a_at
Affymetrix 2.0			Xl2.7551.1.S1_a_at [+] Xl2.7551.2.S1_at Xl2.7551.2.S1_a_at Xl2.19822.1.A1_at

Symbol legend[+]