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Summary Expression Gene Literature (2) GO Terms (26) Nucleotides (167) Proteins (50) Interactants (171) Wiki
XB-GENEPAGE-970083
Gene Symbol:
nfkb2

Gene Name:
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2

Synonyms:
p100-NFkappaB2 , Xp100 ( Add synonyms , Nomenclature history )

Gene Function:
26S proteasome regulatory complex component

Protein Function :
Appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the productio...[+]


InterPro :
Succ DH/fumarate Rdtase cat sf , FRD SDH FAD BS , Succ DH flav su fwd , FAD/NAD-bd sf [+]

Interactants:
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Diseases: 


Disease Ontology:
common variable immunodeficiency

OMIM:
IMMUNODEFICIENCY, COMMON VARIABLE, 10; CVID10

External Links:
 
Xenbase Gene ID XB-GENE-970084 XB-GENE-17344493 XB-GENE-970090
Gene Symbol nfkb2 nfkb2.L nfkb2.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448550
108696243
397698
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine nfkb2 nfkb2.L nfkb2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards NFKB2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nfkb2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nfkb2 Ensembl
zebrafish
ZFIN, AGR nfkb2 ZFIN Ensembl
chicken
GEISHA NFKB2 Ensembl
fruit fly
Publications
First Identification and expression of the Xenopus homolog of mammalian p100-NFkappaB2., Gene 1998            
Most Recent An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm., PLoS One 2006                          
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 6 terms 9 terms
PANTHER nfkb2
KEGG Pathways K04469 K04469 K04469
KOG [O] 26S proteasome regulatory complex, subunit PSMD10
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks nfkb2
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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