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Summary Expression Gene Literature (18) GO Terms (10) Nucleotides (1016) Proteins (42) Interactants (818) Wiki
Gene Symbol:

Gene Name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

14-3-3 zeta , 14-3-3zeta , 14-3-3z , ywhaz-a , ywhaz-b ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction

Protein Function :
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or ph...[+]

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External Links:
Xenbase Gene ID XB-GENE-970616 XB-GENE-6256657 XB-GENE-970622
Gene Symbol ywhaz ywhaz.L ywhaz.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394780
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ywhaz ywhaz.L ywhaz.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen ttpa004p03      
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards YWHAZ OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Ywhaz MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Ywhaz Ensembl
ZFIN, AGR ywhaz ZFIN Ensembl
fruit fly
First Activation of Raf-1 by 14-3-3 proteins., Nature 1994  
Most Recent A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway., Front Physiol 2019                                  
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 3 terms 1 terms
KEGG Pathways K16197 K16197 K16197
KOG [O] Multifunctional chaperone (14-3-3 family)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ywhaz
Antibodies ywhaz Ab1 ywhaz Ab1
Morpholinos ywhaz MO1 , ywhaz MO2 ywhaz MO1 , ywhaz MO2 ywhaz MO1 , ywhaz MO2
ORFs ywhaz ORF1 ywhaz.L ORF1 ywhaz.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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