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Summary Expression Gene Literature (0) GO Terms (28) Nucleotides (133) Proteins (47) Interactants (37) Wiki
XB-GENEPAGE-971396
Gene Symbol:
dstyk

Gene Name:
dual serine/threonine and tyrosine protein kinase

Synonyms:
ripk5 ( Add synonyms , Nomenclature history )

Gene Function:
Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs

Protein Function :
May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. May pl...[+]


InterPro :
Protein kinase ATP BS , Ser/Thr kinase AS , Kinase-like dom sf , Prot kinase dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
hereditary spastic paraplegia 23 [+]

OMIM:
CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT 1; CAKUT1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-971397 XB-GENE-17343241 XB-GENE-971404
Gene Symbol dstyk dstyk.L dstyk.S
Chromosome Chr2 Scaffold38 chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 493205
446954
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dstyk dstyk.L dstyk.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DSTYK OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dstyk MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dstyk Ensembl
zebrafish
ZFIN, AGR dstyk ZFIN Ensembl
chicken
GEISHA DSTYK Ensembl
fruit fly
worm
Publications
First
Most Recent
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Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 0 term 9 terms
PANTHER dstyk
KEGG Pathways K16288 K16288
KOG [T] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dstyk
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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