Gene Symbol: agr2 Gene Name: anterior gradient 2 homolog Synonyms: xagr2, ag2, gob-4, xag-2, pdia17 Add Xenopus synonyms Gene Function: Interactants: ag1(7) , gcg(2) , hhex(2) , ins(2) , neurod1(2) , ptf1a(2) , sfrp5(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >CR760462|Xenopus tropicalis finished cDNA, clone TNeu048m19 AAAGCACTGCTAACTATGGAGACAGTTCTCAAGACCCTGTTTGTTCTCCTTGTGGCTACCTCATTGACTTTAGCCAAGGATTTACCACAAGCTACCAGAGTCTTACAAACACTCTCCAGAGGATGGGGTGACAATCTCGAGTGGGTTCAGACATACGAGGAAGGCTTGTACAAAGCAAAAACAGAAAACAAACCATTGATTCTCATTAACCACAGAAACGACTGCCCCCATTCTCTAGCTCTGAAGAAAGCATTTGCTGAACACCAAGGTATCCAGAAACTGGCAGAAGAGTTTGTGCTTCTCAATGTTGTTTATGATCCTACAGATAAGAACCTTCAGCTTGATGGCCAGTATGTTCCCAAGGTTGTATTTGTAGATCCCTCCCTGGTCGTCAGAGCAGATCTTCCTGGGAAATACTCCAACCACCAGTACACCTATGAGCCAGCAGATATTGATTTGTTGTTTGAGAACATGAAGAAAGCTTTGATCCTGCTGAAAACAGAACTTTAAAAGGGAATATATCACAGGAGATTTTATTTTGAATCGACTATGAATATTGCGGAGGTGTTTGCTAAAGTAATGTTACAATATGTACCAAAGCCAACAACATACAAATTTAGCGGTGTATGAAGGAAACCATTGTTTTTGTCTTTTTAAATGTGTTACCGTTTGCTTCAACTGAATGCAATTTGATTTTTTAAATAAATCTATCTGGGGTTATTTATAAATAAAAAAAAAAAAAAAAAA	Refseq >NM_001086251|Xenopus laevis anterior gradient 2 (agr2), mRNA CCCACGCGTCCGCTAAATATGGAGTCAGTTCTCAAGTCTCTATTTGTTCTCCTTGTGGCTACCTCATTTACTCTAGCCAAAGAGATACCAGCAAAAGTCTCAAAGCCACAAACACTCTCCAGAGGATGGGGCGATAATCTCGAGTGGGTTCAGACGTATGAGGAAGGCTTGTACAAAGCAAAAGCAGAGAACAAACCATTGATGCTTATTAACCACAGAAACGACTGTCCTCATTCTCTAGCTCTGAAGAAAGCATTTGCTGAACACCAAGGTATCCAGAAACTGGCAGAAGAATTTATTCTTCTCAATGTTGTTTATGACCCCACAGATAAGAACCTTCAGCTTGATGGTCAGTATGTTCCCAAGATTATATTTGTAGATCCATCCCTGGTTGTCAGAGCAGATCTTCCTGGGAAATACTCCAACCACCAGTACACCTATGAACCAGCTGATATTGATCATTTGTTCGAGAACATGAAGAAAGCTTTGGTACTGCTGAAAACAGAACTGTAAAAGGAATATATCACAGGAGATTTGATTGCGAATCGACTATGATTATTGCGGAGGTGTATACTAACGTAATGTCGCAATATGTACAACAACATACAAATTTAGCGGTGTATGAAGGAAACCATTGTTTTGTTTTTTTAAATGTGTTACATTTGCTTCAACTGGACGCAAATTGATTTTTTTAAAATAAATCTGCCTGGGGTTATTTATAAATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >CAJ82848|anterior gradient 2 homolog (Xenopus laevis) [Xenopus tropicalis] METVLKTLFVLLVATSLTLAKDLPQATRVLQTLSRGWGDNLEWVQTYEEGLYKAKTENKPLILINHRNDCPHSLALKKAFAEHQGIQKLAEEFVLLNVVYDPTDKNLQLDGQYVPKVVFVDPSLVVRADLPGKYSNHQYTYEPADIDLLFENMKKALILLKTEL UniProtKB	Refseq >NP_001079720|anterior gradient protein 2-B [Xenopus laevis] MESVLKSLFVLLVATSFTLAKEIPAKVSKPQTLSRGWGDNLEWVQTYEEGLYKAKAENKPLMLINHRNDCPHSLALKKAFAEHQGIQKLAEEFILLNVVYDPTDKNLQLDGQYVPKIIFVDPSLVVRADLPGKYSNHQYTYEPADIDHLFENMKKALVLLKTEL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.66700	Xl.25847
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		7 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	AGR2
mouse		MGI	Agr2	All(8) Targeted, knock Out(3) Targeted, other(5)
zebrafish		ZFIN	agr2	2 Lines(s)

Publications
First:		Anterior specification of embryonic ectoderm: the role of the Xenopus cement gland-specific gene XAG-2. [Mech Dev 1998]
Most recent:		Agr genes, missing in amniotes, are involved in the body appendages regeneration in frog tadpoles. [Sci Rep 2013]
		View All Papers 2 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0			Xl.25847.1.S1_at
Affymetrix 2.0			Xl2.25847.1.A1_at

Symbol legend[+]

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