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XB-GENEPAGE-971728
Gene Symbol:
unc45b
Gene Name: unc-45 myosin chaperone B
Synonyms:
cmya4
,
unc45
,
smunc45
,
dicky ticker
( Gene Function: Myosin assembly protein/sexual cycle protein and related proteins Protein Function
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Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell assembly. Is necessary for normal early lens devel...[+]
Interactants:
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Diseases: Disease Ontology:
cataract 43
OMIM:
CATARACT 43; CTRCT43
External Links:
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Xenbase Gene ID | XB-GENE-971729 | XB-GENE-17343539 | XB-GENE-971733 | |||||
Gene Symbol | unc45b | unc45b.L | unc45b.S | Chromosome | Chr2 | chr2L | chr2S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
493194
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108708296
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447296
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | unc45b | unc45b.L | unc45b.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker., BMC Dev Biol 2010 ![]() |
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Most Recent |
Contractile activity is required for Z-disc sarcomere maturation in vivo., Genesis 2015 ![]() |
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All | View All Papers 1 paper(s) referencing morpholinos | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 11 terms | 3 terms | 5 terms | |||||
PANTHER | unc45b | |||||||
KEGG Pathways | K21991 | K21991 | K21991 | |||||
KOG |
[ODR] Myosin assembly protein/sexual cycle protein and related proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | unc45b | |||||||
Morpholinos (on-target & off-target) | unc45b MO1 , unc45b MO2 | unc45b MO2 | unc45b MO2 | |||||
ORFs | unc45b.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



