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Summary Expression Gene Literature (16) GO Terms (5) Nucleotides (159) Proteins (40) Interactants (76) Wiki
Gene Symbol:

Gene Name:
SPC24, NDC80 kinetochore complex component

spbc24 ( Add synonyms , Nomenclature history )

Gene Function:
Myosin class V heavy chain

Protein Function :
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14738735). Required for kinetochore integ...[+]

InterPro :
Ndc80 Spc24

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External Links:
Xenbase Gene ID XB-GENE-974559 XB-GENE-974565 XB-GENE-17342642
Gene Symbol spc24 spc24.L spc24.S
Chromosome Chr3 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 394654
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine spc24 spc24.L spc24.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards SPC24 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Spc24 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Spc24 Ensembl
ZFIN, AGR spc24 ZFIN Ensembl
GEISHA SPC24 Ensembl
fruit fly
First The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment., Curr Biol 2004  
Most Recent Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores., Curr Biol 2005  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 5 terms 5 terms 0 term
KEGG Pathways K11549 K11549
KOG [Z] Myosin class V heavy chain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks spc24
ORFs spc24 ORF1 spc24.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list