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Summary Expression Gene Literature (45) GO Terms (25) Nucleotides (435) Proteins (41) Interactants (231) Wiki
XB-GENEPAGE-974934
Gene Symbol:
parp1

Gene Name:
poly(ADP-ribose) polymerase 1

Synonyms:
parp , ppol , adprt , adprt1 , parp-1 , padprt-1 ( Add synonyms , Nomenclature history )

Gene Function:
NAD+ ADP-ribosyltransferase Parp, required for poly-ADP ribosylation of nuclear proteins

Protein Function :
Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-974935 XB-GENE-974938 XB-GENE-17338936
Gene Symbol parp1 parp1.L parp1.S
Chromosome Chr05 chr5L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100490557
397928
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine parp1 parp1.L parp1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PARP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Parp1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Parp1 Ensembl
zebrafish
ZFIN, AGR parp1 ZFIN Ensembl
chicken
GEISHA PARP1 Ensembl
fruit fly
worm
Publications
First Mono(adenosine diphosphate ribosyl) transferase in Xenopus tissues. Direct demonstration by a zymographic localization in sodium dodecyl sulfate--polyacrylamide gels., Anal Biochem 1984  
Most Recent Kinesin Kif2C in regulation of DNA double strand break dynamics and repair., Elife 2020                                                          
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 17 terms 17 terms 0 term
PANTHER parp1
KEGG Pathways K10798
KOG [KLO] NAD+ ADP-ribosyltransferase Parp, required for poly-ADP ribosylation of nuclear proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks parp1
Antibodies Parp1 Ab1 Parp1 Ab1
ORFs parp1.L ORF1
Clones Horizon Horizon Source BioScience

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