Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (25) GO Terms (14) Nucleotides (199) Proteins (43) Interactants (678) Wiki
XB-GENEPAGE-977361
Gene Symbol:
dvl3

Gene Name:
dishevelled segment polarity protein 3

Synonyms:
dishevelled3 , dsh3 ( Add synonyms , Nomenclature history )

Gene Function:
wnt signal transduction

Protein Function :
Involved in the signal transduction pathway mediated by multiple Wnt genes. Required during ciliogenesis for the docking of basal bodies to the apical plasma membrane.


InterPro :
DIX dom sf , Ubiquitin-like domsf , DIX , PDZ [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
autosomal dominant Robinow syndrome 1

OMIM:
ROBINOW SYNDROME, AUTOSOMAL DOMINANT 1; DRS1 [+]

External Links:
1/4
 
Xenbase Gene ID XB-GENE-977362 XB-GENE-977365 XB-GENE-17335212
Gene Symbol dvl3 dvl3.L dvl3.S
Chromosome Chr05 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 100144702
444527
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dvl3 dvl3.L dvl3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DVL3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dvl3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dvl3 Ensembl
zebrafish
ZFIN, AGR dvl3a ZFIN Ensembl
chicken
GEISHA DVL2 Ensembl
fruit fly
worm
Publications
First Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis., Proc Natl Acad Sci U S A 2005  
Most Recent Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled., J Cell Biol 2019                
All View All Papers 7 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 7 terms 0 term
PANTHER dvl3
KEGG Pathways K02353 K02353
KOG [R] Dishevelled 3 and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dvl3
Antibodies Dvl2 Ab1 , Dvl3 Ab1 , dvl3 Ab3 Dvl2 Ab1 , Dvl3 Ab1 , dvl3 Ab3 dvl3 Ab3
Morpholinos dvl3 MO1 , dvl3 MO2 , dvl3 MO3 dvl3 MO1 , dvl3 MO2 , dvl3 MO3 dvl3 MO1 , dvl3 MO2 , dvl3 MO3
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556