[provisional- machine annotated only] Gene Symbol: grm3 [Predicted: Source is Human Entrez Gene] Gene Name: glutamate receptor, metabotropic 3 [Predicted: Source is Human Entrez Gene] Synonyms: mGluR3 Add Xenopus synonyms Gene Function: Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits, G-protein coupled receptor superfamily Interactants: grm1(4) , grm6(2) , suclg1(1) , View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene
mRNA		NCBI Nucleotide >XM_002935246|PREDICTED: Xenopus (Silurana) tropicalis metabotropic glutamate receptor 3-like (LOC100492610), mRNA CTCTCTGTGGCATGTTTGTACTGTGCTACATCTACAAGGAATGTAATGCCACTGCAACGATCTACAGCAAATTACTTTGCTACAGAGGAATAACAAATTGGGCTTTTCGCTGTCATATCAAGCCACAAAAGTCATGAAGACCAGCCTTCAGGTCCTTCTGTTAGCTTTATTTTCCAAAGCTGTATTGCTTTCCTCAAGTGACCACAACTTTGTGAGGAAAGAAATAAAGTTTGAGGGTGACCTTGTTTTAGGAGGGTTGTTTCCTATAAATGAGAAAGGTGGGGGAATGGATGAATGTGGCAGGATTAATGAAGACCGAGGCATCCAGCGACTTGAAGCTATGCTTTTTGCAATTGATCAGATTAACAGAGATAGTTCACTTCTTCCAGGAGTCAAATTAGGAGTTCATATCTTGGATACCTGTTCAAGAGACACATATGCTTTGGAGCAATCCCTTGAGTTTGTTAGGGCTTCTTTAACTAAAGTGGATGAAGCGGAATATATGTGCCCAGATGGGTCATATGCCATTCAAGAAAACAGTCCCTTGCCTATCGCTGGAGTCATTGGTGGGTCCTACAGCAGTGTTTCTATACAGGTTGCTAATTTGTTGAGACTTTTCCACATTCCTCAAATAAGCTATGCTTCCACTAGTGCCAAACTTAGTGACAAATCTCGTTATGACTACTTTGCTAGGACAGTGCCACCAGACTTCTATCAAGCTAAGGCAATGGCTGAGATTTTAAGGTTCTTTAACTGGACATATGTGTCTACTGTTGCCTCAGAAGGAGACTATGGGGAGACAGGAATTGAAGCCTTTGAACATGAAGCAAGGTTAAGAAATATTTGCATTGCCACATCAGAAAAAGTTGGGAGGTCTAATCTTAAAAAGTCTTATGATAATGCCATAAAGGAGCTCTTACAAAAGCCAAATGCAAAAGTTGTTGTACTTTTTATGAGGAGTGACGACACTAGGGAGCTTCTGGCAGCTGCTAATAGGTTTAATGCTTCTTTTACATGGATTGCCAGTGATGGATGGGGAGCCCAAGAAAGCATTGTTAAGGGTAATGAGCATATTGCATATGGGGCAATAACACTGGAACTTGCTTCTCACCCTGTTAAAGAATTTGACAAGTACTTCCAAAGCCTTACACCTTACAACAACCACCGTAATCCATGGTTCAAAGATTTCTGGCAGCAAAAGTTTCAGTGTTCATTACAGAACAAAAACCAGCAAGTAAAGTTTTGTGATAAGCGTCTCAATATCAACAGTTCCAACTACGAACAAGAATCCAAAATAATGTTTGTGATAAATGCTGTTTATGCAATGGCCTATGCATTACACCAAATGCAGCGCACTGTGTGCCCAAACACCAACATACTGTGTGATGCCATGAAGGTCTTAGATGGAAAAAAGCTCTATAAAGATTATCTACTGAAAGTAAATTTTACAGCTCCTTTTATACCACCCAGTAATACAGACAGCATTGTGAAATTTGATGCATATGGAGATGGAATTGGTTTATACAATGTGTTCAATTTCCAGTATCACAATGGTAAATATTCCTACCTGAAAATTGGCCAGTGGGCAGAAACCTTGTCACTGGATGTTGACATAATACAGTGGTCAAAAAGTTTGGTTCCAACATCACAGTGTAGTGACCCCTGCGCTCCAAATGAAATGAAGAATATGCAACCAGGAGATGTATGCTGCTGGATTTGTATCCCATGTGAGAAATACGAGTACCTTGCTGATGAGTTCACATGCATTGACTGTGGGGAAGGACGATGGCCTACCGCTGACCTAACCAGTTGCTTTGATCTACCAGAAGATTACATTAAGTGGGAGGATGCCTGGGCAATAGGGCCAGTGACCATTGCATGCCTTGGATTTGTATGTACTTGCCTGGTTGGAGGAGTCTTTATCAAAAACAATAGCACACCTTTGGTGAAGGCATCAGGAAGGGAACTCTGCTATATTCTCTTGATTGGAGTTTTTATGTGTTATTGTATGACATTTTTCTTCATAGCCAAACCTTCTCCTGTCATATGCACCCTTCGACGTTTGGGACTTGGAACATCTTTTGTTGTTTGTTATTCTGCTCTACTGACCAAGACAAATCGCATTGCCAGGATATTCAGCGGTGTAAAGGATGGTGCCCAAAGACCAAAATTCATCAGTCCCAAATCCCAAGTTGTCATATGTCTCAGTCTTATCTCAGTTCAGATTGTTGTTGTATCTGTATGGCTCATGTTGGAATTCCCTGGCACAAGACGCTATACACTTCCTGAAAAAAGAGAAACTGTTATATTGAAATGCAATGTCAAAGATTCCAGTATGCTAATTTCACTGACATATGATGTGGTCCTGGTGATATTATGTACTGTATATGCCTTCAAAACAAGGAAATGTCCAGAAAATTTTAATGAAGCCAAGTTCATTGGATTTACAATGTACACAACTTGCATTATTTGGCTTGCTTTCCTGCCTATATTTTATGTCACATCAAGTGACTACAGAGTCCAAACTACAACAATGTGCATCTCAGTAAGCCTGAGTGGCTTTGTAGTTCTGGGGTGCTTGTTTGCGCCAAAAGTTCATATTATCCTGTTTCAACCACAGAAAAATGTCGTAACACACAGACTACATCTAAATAGGTTCAGTGTTAGTGGTACAGCAACCACATACTCACAATCCTCTGCAAGTGCACATTACACACCAACCATTTGCAATGGAGGAGAAGTTCTCGACTCCACCACGTCATCCTTATAAATGTGATCAGAATCTATGTCTTGAAGATTTTTAGACTGTTAGATTTTATGCACTTGTGCAGTTCTGTAACTTTTTTTAGAAAAAAAACAAAAATATTTTTGAGGACTGTATAGCTTAATGTTCTAGAGCTTTTTAGACTTGTTCAATGACCACAGCTGTTGACACATTTAGACGATGTGTAAATAGGGTGCATTCTCTACACCAGAGGCAAGCAATGTCTAGTGCTCCAGATGTTGTGAAACTACAGGGCAATACCCACAACTGAATACAATGTGGGATGGTGGAAGCTGTAGCTCTATAACAAATGGAGTGCAAGAGGTTACCTGCTCCTGCTCAACACTATCTGCAGTGTCCACTTAACAGTAATACAATAACCGACATCTGCCATTTCAGTATTAAATGTCTTTTACTTTCATATGATTTTTTTTTTGTAAACTAGGTTATTGTTGTAAC
Protein		NCBI Protein >XP_002935292|PREDICTED: metabotropic glutamate receptor 3-like [Xenopus (Silurana) tropicalis] MKTSLQVLLLALFSKAVLLSSSDHNFVRKEIKFEGDLVLGGLFPINEKGGGMDECGRINEDRGIQRLEAMLFAIDQINRDSSLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENSPLPIAGVIGGSYSSVSIQVANLLRLFHIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEHEARLRNICIATSEKVGRSNLKKSYDNAIKELLQKPNAKVVVLFMRSDDTRELLAAANRFNASFTWIASDGWGAQESIVKGNEHIAYGAITLELASHPVKEFDKYFQSLTPYNNHRNPWFKDFWQQKFQCSLQNKNQQVKFCDKRLNINSSNYEQESKIMFVINAVYAMAYALHQMQRTVCPNTNILCDAMKVLDGKKLYKDYLLKVNFTAPFIPPSNTDSIVKFDAYGDGIGLYNVFNFQYHNGKYSYLKIGQWAETLSLDVDIIQWSKSLVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEKYEYLADEFTCIDCGEGRWPTADLTSCFDLPEDYIKWEDAWAIGPVTIACLGFVCTCLVGGVFIKNNSTPLVKASGRELCYILLIGVFMCYCMTFFFIAKPSPVICTLRRLGLGTSFVVCYSALLTKTNRIARIFSGVKDGAQRPKFISPKSQVVICLSLISVQIVVVSVWLMLEFPGTRRYTLPEKRETVILKCNVKDSSMLISLTYDVVLVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNVVTHRLHLNRFSVSGTATTYSQSSASAHYTPTICNGGEVLDSTTSSL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.61452
Unigene EST Profile		EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	GRM3
mouse		MGI	Grm3	All(6) Targeted, other(4) Targeted, knock Out(1)
zebrafish

Publications
First:		Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors. [EMBO J 1994]
Most recent:		The neuroactive peptide N-acetylaspartylglutamate is not an agonist at the metabotropic glutamate receptor subtype 3 of metabotropic glutamate receptor. [J Pharmacol Exp Ther 2009]
		View All Papers

Functional Ontologies
GO: Molecular:		G-protein coupled receptor activity metabotropic glutamate, GABA-B-like receptor activity
Biological:
Cellular Component:		membrane
EC:
KOG:		[PT] Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits, G-protein coupled receptor superfamily

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.39654.1.S1_at [+] StrEns.3509.1.S1_s_at
Affymetrix 2.0

Symbol legend[+]

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