dusp6 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (21)

Nucleotides (162)

Interactants (49)

XB-GENEPAGE-978215

Gene Symbol: dusp6 Gene Name: dual specificity phosphatase 6 Synonyms: MAP kinase phosphatase, mkp3, pyst1 Add Xenopus synonyms Gene Function: MAP kinase phosphatase Interactants: mapk1(19) , cdk20(4) , mos(4) , ccnb1.2(3) , cdk1(3) , fgf8(3) , mapk8(3) View All	1/4

XB-GENE-978216

XB-GENE-978223

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001045578\|Xenopus (Silurana) tropicalis dual specificity phosphatase 6 (dusp6), mRNA CAGGGACTGGTCGGCCTCAGAACCACAGGGACATTGATCAAATAGACGAGCTGCTCGTCCTGTTGGAGGGGGACAATCCCTTAGGAGGAGGGGCAGCAGTGAGAGGGTTGTGTGCATGCAGACAGCCCCAGCATCAGCCATTCAGCTAACTCGTTGACTCGTTGGATTTGTGGACGGGGAAGGCGCCTCTCTGTTCCCCCATTGACAAGAGCCCGGGCTGCTGCATTCCCGCTCCGCGGCACATGCCTGTGTAGTCGGGCCCCTGGGGACAGCTCTCACTCCGCCCGGCCTCGCCCCCTGTTCTCTCCTCAATGCTAGAGAAGTTGAGACCCGCTGCGCCCCTGGATATGGCGGTCGGGAAGTCGGTGGCCTGGCTGAACGAGCAGCTGGATCTGGCCAACGAGCGTCTCCTACTCATGGACTGCAGGGCGCACGAACTGTACGAGTCGTCTCACATTGAGGCGGCCATCAACGTTGCCATCCCGGGTATCATGCTGCGGCGCCTCAAGAAGGGCAACTTGCCCATACGATCGCTCTTTGCCTGCGGGGAGGACCGGGAGAAGTTCGCCCGCAGATGTGGCACCGACACGGTTGTACTGTACGATGAGAGCAGCTGCGACTGGAATGAGAATACAGGCGGGGAGTCGGTGCTGGGGCTGCTCATGAAGCGGCTGAAGGATGAGGGCTGCAGGGCTTACTACCTGGAAGGTGGATTCAATAAGTTCCAGGCTGAGTATCCTATACATTGTGAAACCAATCTGGATAGTTCCTGTGGCAGTAGCTCTCCACCGGTCCTTGGTTTGGGAGGCCTCCGGATAAGTTCTGACTCTTCATCAGATATCGAATCTGACATTGACAGGGATCCAAACAGTGCTACAGATTCAGATGGTAGTCCTCTATCCAACACTCAACCATCATTTCCTGTTGAGATTCTACCCTATCTTTACCTTGGCTGTGCCAAGGATTCTACGAATTTGGATGTTTTGGAAGAGTTTGGTATTAAGTACATCCTGAATGTGACACCAAACTTGCCTAACCTTTTTGAAAATGCTGGGGAGTTTAGATACAAGCAGATTCCCATTTCGGACCATTGGAGCCAAAACCTCTCTCAATTTTTTCCAGAAGCCATCTCATTTATAGATGAAGCCCGGGGTAAAAGCTGTGGAGTGTTGGTGCATTGCTTGGCTGGCATCAGCCGATCTGTCACAGTCACAGTAGCTTATTTGATGCAGAAGCTTAACCTCTCCATGAATGATGCCTACGATATTGTCAAGATGAAGAAATCCAACATCTCTCCTAACTTTAACTTCATGGGTCAGTTGCTGGATTTTGAAAGGACATTGGGGCTCAACAGTCCATGTGACAATCGAGTTCCAGCACAGCAGTTATATTTTACAGGTCCAGCCAACCAAAATGTATATCAGGTTGATTCTATGCAGTCCACGTGAAACTGAACTCTTTATCTTTTCGTGGTAAAGATCATTCCTCTACAGAAATCTTTCTCTTTAAATCTGTCAAGAGTGCATTGACAGATGTGATTGGTTCAAGGAGGTCATTGTTGGGCGTAAAGAAACAAACCAGTTTATTAAAGTTACAGTTGCACTTGCAATGGAAGAAAGCTGATTAGTTCAACTCTCCAGATCACTTGGAGATAAGCCTTAGATGCCTTGAAATGATTTGGCAAAGCTAATATGACACTGCCTTTGTAATGCAGTGGTTTTTAGTTCCAAACAAGCAACAGCACAGCTGGACCCAATACCAGAGATTTATCTTTGAAAGGTTTGGAAAGGATAAGGGTGCAGATCATTTGTCTTCTGTGAAGACTGGTTCTCCTGATGTTTAAAGTAGCCAAAGAATTACGATTAAACTTCTGATGCATTTGAAGTTTTTTTTGGTCTTTACCTTTTTACAGTTGTAAATATCAACTTCTCCTATGTAGCACTGTCATTTCCCTTTTTTATTTTTTCCCTCCTTTTAAAATACAAAGTTATTTTTTTTTTTCTTTAAACCCACACCTCCCTGCTCATCCTTTAAAAGCAATTGTAGCATAGCAGTTATGGGGTAGGATGGTTGTGTACTTTGCATAAAAGTGCTGATAACATTTTGATTCACATTAATGCATAGCAGGAATATTCAACCTTAACTGTTTGTATAGCATGCTACTCCACTGAGTAAATTGGGGCATGCTGGGAGGTATAGCTCTGCAGAATCTGAAGCCAGAGGTTGACTATCCCTGATGTATAGTTTTGTTGCCTGAGCTGCTTGTAAACCTCTCTCTCTTAGTGGTTTCATGTTTTAACATATTAATTGCTCTGAAAATTGTTAATGTGAATTATCTCTGTCCTTTTTGTTTAGGGAGTTTCACCTCAAATGCTAAAATGTTTTTGTTTTTTTTCTTTTTCCTACAATATAAACTGGAAGTATGTATGTACCAGTGTCTTGCAAAGCTTCGATTGCACATTGATTGCCAATAAGGGAGAAATGTTACACTCCCGAATGTCCACGGAGTAAAGTTTTATGATAAAAATTTATTATAGACTTGTAAATCTTTAAATTATTAATAAATTCCTATTTTTGGTTATTGAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001089787\|Xenopus laevis dual specificity phosphatase 6 (dusp6), mRNA AATTGGGGACGAGGAAGGCGCCGCTTTGCAGTTCCATTGACAAGAGAGCTCAGGCTGCCGCTGCTTCAGTGTCACATGCCTGTGTAGTCGGGCCCCTGCGGACAGCTCTCAGTTGGCCCGGCCTCGCCCCCCGTGCTCTCCTCAATGCTAGAGAAGTTGAGACCCGCTGCGCCCTTGGACATGGCGCTCGGTAAATCGGTGTCGTGGCTGAACGAGCAGCTGGACGTGGCCAACGAGCGGCTTCTTCTGATGGACTGCAGGGCGCACGAGCTGTACGAGTCGTCTCACATCGAGGCGGCCATGAACGTGGCCATCCCGGGCATCATGCTGCGCCGCCTCAAGAAGGGAAACCTGCCCATCCGGTCGCTCTTTGCCTGCGGGGAGGACCGGGACAAGTTCGCCCGCCGATGCGGCACCGACACGGTTGTACTGTACGACGAGAACAGCTGCGACTGGAACGAGAACACGGCCGGCGAGTCGGTGCTGGGGCTGCTCATGAAGCGGCTGAAGGACGAGGGCTGCAGGGCTTTCTACCTGGAAGGTGGATTCAACAAGTTCCAATCTGAGTATCCTATACATTGTGAAACCAATCTGGATAGTTCCTGTAGCAGTAGCTCTCCACCCGTCCTTGGTTTGGGAGGCCTCCGGATCAGTTCTGACTCTTCGTCAGATATTGAATCTGACATTGACAGGGATCCCAGCAGTGCAACAGATTCAGACGGTAGTCCTCTATCCAACCCTCAGCCATCATTTCCCGTTGAGATCTTACCCTACCTTTACCTCGGTTGTGCTAAGGATTCTACTAACCTGGATGTTTTGGAAGAGTTTGGCATTAAGTACATACTGAACGTGACACCAAACTTGCCTAATCTTTTTGAAAACGCGGGGGAATTTAGATACAAGCAGATTCCCATTTCGGACCATTGGAGCCAAAACCTGTCTCAGTTTTTTCCAGAAGCCATCTCGTTTATAGATGAAGCCCGGGGTAAAAGCTGTGGAGTATTGGTGCATTGCTTGGCCGGCATCAGCCGATCGGTTACAGTCACTGTAGCTTATTTGATGCAGAAGCTGAACCTCTCCATGAATGATGCCTACGATATTGTCAAGATGAAGAAATCCAACATCTCTCCTAACTTTAACTTCATGGGTCAGTTGCTGGATTTTGAAAGGACATTGGGGCTTAGCAGTCCATGTGACAATCGAGTCCCAGCTCAGCAGTTATATTTTACAAATCCAGCCAACCAAAATGTATATCAAGTTGATTCTATGCAGTCCACGTGAAACTGAACTGGCAATCGTTGGTGGTAAAGATCATTCCTCTACAGAAATCCTTCTCTTTAAATCTGTCAAAAAGTGTATTGACAGATGTGATTGATTGGTTGAAGGAGGTCGTTGTTGAGGCGTAAAAATAAAACCGTTTATTAAAGTTACAGTTGCACTTGCAATGGAAGAAAGCTGATAAGTTTATGTCTTCAGTTCACTCGGAGATAAGCCTTAGATGCCTTGAAATGATTTGGCAAAGCTAATATGACACTGCCTTTGTAATGCAGTGGTTTTAGTTCCAAACGAGAGACAGCACAGCTGGACCCAATATAAGATATTAATCCTGAAATGTTTGGAAAGGAGAGGGTGCAGATCATTTGTCTTCTGTGAAGACTGGTTCTCCTGATGTTTAAAGGAGCCAAAGAATTATGAGTAAACTTCTGATGCATTTGAAGTTTTTTTTTTTTTTTGTTTTTTTTTGGGGGGGGTTGGGCTTTACCTTTTTACAGTTACTGTAAATATTAACTTCTCTTACATAGCACTGTCATTTCACTTCATTTACTTTTTTTTGACCTTTAAAATACGAAGGTGTTTTTTTTTTTTTTTTCTTCTTCTCTTACCCCACACCTCCCTGACAACCTTTAATAGCAACTGTAGCATAGCAATTTATGAATTGGGGATAGGAGGGTTTTTGTACTTTGCATAAAAGTACTGATGTAATTTTGATTCACATTAATGTATAGCAGGGATATTCAACCTTAACTGGCCCAGCTGTGGCATAGCATACTACTCCACTGAGTAAGTTGCGGAGTGCTGGGAGGTGTAGTTCTGCAGAATCTGAAGCACCAGAGGTTGACTATCCCTGATGTATAGTTTTGTTGCCTGAGCTGCTTGTAAGCCCCTTTCTATTAGTGGTTACTTGTTTTTAACATATTAATTGCTCTGAAAATTGTTAATGTGAATTACTTCTGTCCTTTTTGTTTAGGGAGTTTCACCTAAAATTCTATGTTATGTTTTTTTGTTATTTTTCCTACAATATAAACTGGAAGTATGTATGTACCAGTGTCTTGCAAAGCTTCGATTGCACATTGATTGCCAATAAGGGAGATATGTTAACACTCCCGATTGTCCAAGGAGTAAAGTTTTATGATAAAATTTATTATAGACTTGTAAATCTTTAAATTATTAATAAATTCCTATTTTGGTTATTGAATAGTGAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001039043\|dual specificity phosphatase 6 [Xenopus (Silurana) tropicalis] MLEKLRPAAPLDMAVGKSVAWLNEQLDLANERLLLMDCRAHELYESSHIEAAINVAIPGIMLRRLKKGNLPIRSLFACGEDREKFARRCGTDTVVLYDESSCDWNENTGGESVLGLLMKRLKDEGCRAYYLEGGFNKFQAEYPIHCETNLDSSCGSSSPPVLGLGGLRISSDSSSDIESDIDRDPNSATDSDGSPLSNTQPSFPVEILPYLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFRYKQIPISDHWSQNLSQFFPEAISFIDEARGKSCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLNSPCDNRVPAQQLYFTGPANQNVYQVDSMQST	Refseq >NP_001083256\|dual specificity phosphatase 6 [Xenopus laevis] MLEKLRPAAPLDMALGKSVSWLNEQLDVANERLLLMDCRAHELYESSHIEAAMNVAIPGIMLRRLKKGNLPIRSLFACGEDRDKFARRCGTDTVVLYDENSCDWNENTAGESVLGLLMKRLKDEGCRAFYLEGGFNKFQSEYPIHCETNLDSSCSSSSPPVLGLGGLRISSDSSSDIESDIDRDPSSATDSDGSPLSNPQPSFPVEILPYLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFRYKQIPISDHWSQNLSQFFPEAISFIDEARGKSCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTNPANQNVYQVDSMQST

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.10337 [+] Str.43825	Xl.31935
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		5 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	DUSP6
mouse		MGI	Dusp6	All(3) Targeted, other(1) Targeted, knock Out(2)
zebrafish		ZFIN	dusp6

Publications
First:		The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34. [Hum Genet 1994]
Most recent:		Imparting regenerative capacity to limbs by progenitor cell transplantation. [Dev Cell 2013]
		View All Papers

Functional Ontologies
GO: Molecular:		MAP kinase tyrosine/serine/threonine phosphatase activity phosphoprotein phosphatase activity protein tyrosine/serine/threonine phosphatase activity
Biological:		protein amino acid dephosphorylation
Cellular Component:
EC:
KOG:		[V] Dual specificity phosphatase (alt_id KOG:1717)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.10337.1.S1_at [+] Str.43825.1.A1_at	Xl.1002.1.S1_at
Affymetrix 2.0			Xl2.31935.1.S2_at

Symbol legend[+]