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Summary Expression Gene Literature (17) GO Terms (4) Nucleotides (52) Proteins (20) Interactants (64) Wiki
XB-GENEPAGE-979946
Gene Symbol: dio1

Gene Name: deiodinase, iodothyronine type 1

Synonyms: type I iodothyronine deiodinase , type 1 deiodinase , deiodinase I ( Add synonyms , Nomenclature history )

Gene Function: thyroxine 5'-deiodinase

Protein Function :
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).


Interactants: Loading ...
 
Xenbase Gene ID XB-GENE-979947 XB-GENE-979948 XB-GENE-17345940
Gene Symbol dio1 dio1.L dio1.S
Chromosome Chr04 chr4L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100497874
Entrez Gene: 733447
mRNA RefSeq RefSeq
Protein RefSeq RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine dio1 dio1.L dio1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DIO1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dio1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dio1 ZFIN Ensembl
chicken
GEISHA DIO1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Type I iodothyronine deiodinase is a selenocysteine-containing enzyme., Nature 1991  
Most Recent Reference gene identification and validation for quantitative real-time PCR studies in developing Xenopus laevis., Sci Rep 2018              
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 4 terms 0 term
PANTHER dio1
KEGG Pathways K01562
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon
Affymetrix 1.0 StrJgi.22.1.S1_at
Affymetrix 2.0 Xl2.17649.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.2


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