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Summary Expression Gene Literature (9) GO Terms (10) Nucleotides (1146) Proteins (38) Interactants (107) Wiki
Gene Symbol: atf4

Gene Name: activating transcription factor 4

Synonyms: atf-4 , creb2 , txreb , creb-2 , taxreb67 , atf4-a , atf4-b ( Add synonyms , Nomenclature history )

Gene Function: basic-leucine zipper (bZIP) transcription factor

Protein Function :

Interactants: Loading ...
Diseases:  Disease Ontology: microphthalmia

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
Xenbase Gene ID XB-GENE-983841 XB-GENE-983847 XB-GENE-6251859
Gene Symbol atf4 atf4.L atf4.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448005
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine atf4 atf4.L atf4.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards ATF4 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Atf4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR ZFIN, AGR atf4a atf4b ZFIN Ensembl
fruit fly
First The metabotropic GABAB receptor directly interacts with the activating transcription factor 4., J Biol Chem 2000  
Most Recent Aβ1-42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons., EMBO Rep 2018  
All View All Papers 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 5 terms 5 terms
KEGG Pathways K04374 K04374 K04374
KOG [K] Activating transcription factor 4
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks atf4
ORFs atf4 ORF1 atf4.L ORF1 atf4-iii ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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