masp1 Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-984452

[provisional- machine annotated only]

Gene Symbol: masp1 [Predicted: Source is Human Entrez Gene]

Gene Name: mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) [Predicted: Source is Human Entrez Gene]

Synonyms: masp-1 Add Xenopus synonyms

Gene Function: Trypsin

Interactants: masp2(3) , c1r(2) , c1s(2) , abcc1(1) , c11orf58(1) , fcn1(1) , wls(1) View All

XB-GENE-984453

XB-GENE-984458

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene
mRNA	Refseq >NM_001097405\|Xenopus (Silurana) tropicalis mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (masp1), mRNA AGAACAAAGCTAGAGCCAGGCAGAGCAGCTGTGGGGAGCAAACACACACACACAAAGGAGATAGAAGACAGGGAAAGGAAAATCTCTGCCAATATGAGGATCCCTCTACTCTTCTCCTTCTTCTTGTGGATGCTGTCGGAAGCAGAAGTAATTCAGCTTACTGATACTTTTGGTGAAATCCGGACACCTAATTTTCCTGACTCTTACCCTAGTGATTCAGAGGTGACATGGAACATCACAGTCCCTGAGGGTTTCCGGCTTAAGCTCTATTTTATGCACTTTGATCTGGAACCATCTTATCTGTGCGAGTATGATTATGCCAAGGTGGAGACTGAAGACCAGGTTATTGCCTCCTTCTGTGGGAAAGAAAGCACCGACACAGAACAAGCTCCGGGCAAACAGATGATTACATCACCTGGTAATTTCCTGAGCCTCACTTTTCGCTCTGACTTCTCCAATGAGGAGCGCTTCACAGGCTTCGATGCTCATTATAGCGCAATAGATATAGACGAGTGTACAGAAAAAAATGATGAAGACCTGGTTTGTGACCATCACTGCCACAATTACATTGGAGGGTTCTATTGCTCATGTAGATTTGGTTACCTCTTGCACACGGATAACAGAACATGCAAAGTGGAATGCAGTGATAATCTTTTTACCCAAAGAAGTGGGTTGATTTCAAGTCCAGACTATCCCAGTTCGTATCCCAAGAGCTCAGACTGCCGCTATAGGATTGAGCTAGAAGAAGGCTTTGTAATAAATCTGCATTTTGATGACAACTTTGATGTTGAGGACCATCCGGAAGTCACATGCCCTTATGATTACTTAAAGATCAAAACTGGGAAAAAAGAAATTGGTCCACTGTGTGGAGAGAAATCACCAGGGAGGATTGAAACCGGAAGCAACAGTGTTCAGATTCTGTTCCACAGTGACAACTCAGGGGAAAATGGAGGATGGAGATTCTCCTACTCTGTATCAGGTACTCCATGCCCAAATCTGCGTCCACCAATCAATGGAAAACTTGAACCTTCTCAGGCTGAATATACATTTAAAGATCAGGTTGTAATTAGCTGCAACCAAGGGTACAGAGTGCTGAAGGATAATGTTGAGATGGAGAGTTTCCAGATTGAATGTCGAAAAGATGGAACATGGAGTAACCAAATCCCAACGTGTCAAATTGTTGACTGTAAGACACCAAAGGAGATAGAGAATGGATTCATCACCTACTCTACAGCAGAAAATCGTACCACATTCCAGTCCAGCTTTAACTATTCCTGCAGGGAACCTTACTACACTATGGTTCCAAACATAACAAGTGTGTATACCTGTGATGCAAGTGGAGAGTGGAAAAACCAGGAGACTGGAGCAAAGTTTCCTACTTGTCAGCCAGTGTGTGGGAAACCAACTCGACCACTCCCTGGAATAGTGAAGCGTATCATTGGAGGACGGAATGCAGAGCCGGGATTCTTCCCATGGCAAGTACTAATTGTTGTAGAAGATCTTTCACGAGTTCCTATGAACAAATGGTTTGGTGGTGGAGCTCTTATCTCAGACTCCTGGATACTGACGGCCGCTCATAACTTAAGATCTCAACGCCGTGACAACACAGTGATGCCAGTTTCCAAAGAACATGTCACTGTATATTTGGGTTTGCACGACGTGCGAAGTAAGATGGATGCAGTAAACAGAACCATAGAAAAAATCATATTGCATGAAATGTTTGACCCAGAGAGTTATAACCATGACATTGCTCTAGTCAAGCTGAATGAAAAGGTAATAATGAACCAGTATGTGATGCCAGTCTGCCTACCAGAGCTTGAGCATGAGTTGGAAGGTCCTCAGCCTAACACTCTAGGCCTTGTGGCAGGCTGGGGCATATCTAATCCTAACATTACTGTAGATGAAATTATCAGCTCAGACATGAGGACACACTCTGCTATTCTACAGTATGTCAAGCTTCCAGTGGTGCTTCATGAAGTGTGTAAGGAAAGCTATGAATCCCGCTCAGGAAATTATAGTGTTACAGAAAATATGTTTTGTGCTGGTTATTATGAAGGCGGGAAAGACACCTGTCTTGGGGACAGTGGAGGTGCATTTATTATGCAGGACACTGACACAAAGCGTTGGGTGGCACAGGGGTTAGTTTCATGGGGTGGGCCTGAAGAATGTGGGAGCAAGCAGGTCTATGGCGTCTATACTAAAGTATCTAATTTTGTGGACTGGGTAGATGATAAACTTAAGTCCTAAACTGGCCAAATCTAAACTATGACTTATAGCTGTTAGCCACAATATCAAAGCCCAGAAAAGAGTCAGACAATCATAGCTCATATTTTATAAAAAGTATTTATGACTATATTAAATAATGTCTGTTTGTTATATGTTTTTGCTTTTTTACACTGCTGTAGTAGAGTGTGAAAAATGGCATCATTCTGTTGTTCAAACTCAAAGCTCTGATAAGGCCAATGTTGTCTTAAGCATAATGCGCAAAATCCATTTTTTAACATTGTCTTATACAATGTATACAACTGTGAAATTCAATATTGATTGCTACAGTAGAGCCACATATTTGTGGAATAGTTGTGTTTCACTATAAAATGCCTCTGCCTAGCAAGCAGCATGGAATCTTCTATGCATATTTATACATTTACACTTGCATAGATCGAATGTTCAAAGTTTGAAAGTGAAATGTAATATCTCACGAACAGTTGTGCTTCTTAACAAAGCAGCTATTACACTGGTACTGTATTTCCAATTGAAAATATTTAGGAACCAAATAGTATAATAAAGAATTTCTGTTAATAAAAAAAAAAAAAAA	Refseq >NM_001088871\|Xenopus laevis mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (masp1), mRNA TGCTAAAGCCAGGCAGTGCAGCTGTGGGGAGCAAATACACAAACACAAAGGAGATAGAAGACGGGGAGAAGGAAAATCTCTGCCAACATGAGAATACCCCTGCTCTTCTCCATCTGCTTGTGGATGTTATCAGAAGCAGAAGTCATTCAGCTTACTGATATGTTTGGTGAAATCCGAACACCCAACTTTCCTGACTCTTACCCTAGTGAATCAGAGGTGACGTGGAACATCACTGTCCCGGAGGGTTTCCGGCTTAAACTTTATTTTATGCACTTTGATCTGGAACCATCTTACCTCTGCGAGTATGATTATGCCAAGGTGGAAACTGAGGACCAGGTTATTGCCACCTTCTGCGGGAAAGAAAGCACTGACAAAGAACAAGCTCCAGGTCAACGGATTATTACATCCCCTGGTAATTTCCTGAGCCTCACCTTTCGGTCTGACTTCTCCAATGAGGAGCGCTTCACAGGTTTTGATGCTCATTATAGTGCAAAAGATATAGACGAGTGTACAGAGAAAAGTGATGAAGACCTAGTTTGTGACCATCACTGCCACAATTACATTGGAGGGTTCTACTGCTTCTGCAGATTTGGTTACCTCTTGCACACGGATAACAGAACATGCAAAGTGGAATGCAGTGATAATCTTTTCACCCAAAGAAGTGGGTTCATTTCAAGTCCAGACTATCCCAGTCCATATCCCAAGAGCTCAAACTGCCGCTATAGGATTAAGCTAGAAGAAGGTTTTGTTATAAATCTCCATTTTGATGACAGCTTTGATGTTGAGGATCACCCTCAAGTCACTTGCCCTTATGATTTCGTAAAGATCAAAAGTGGCAAAAAAGAATTTGGACCTCTGTGTGGAGAGAAGTCACCAGGGACAATAGAAACTGGAAGCAACAGCGTTCAGATTCTCTTCAATAGTGACAATTCTGGGGAAAATGGAGGATGGAGATTGTCCTACTCTGCAACAGGTGCACCATGTCCAAATCTGCACCCGCCAATCAATGGGAAACTTGAACCTTCTCAATCTGAATATATATTTAAAGATCAGGTTGTAGTTAGCTGCAACCAAGGGTACCAAGTGCTGAAGAATAATGTTGAGATGGAGAGTTTCCAGATTGAATGTCGAAAAGATGGAACATGGAGTAACCAAATTCCACCGTGTCAAATTGTTGACTGTAGGACACCAAAGGAGATAGAGAATGGATTCATCACTTACCCTACAGCAGATAATCATACCACATACCAGTCCAGCTTTAACTATTCCTGCAGGGAACCTTACTATATTATGGTTCCAAACATAACAAGTGTGTATACTTGTGATTCAAATGGAGAGTGGACCAGCCAGGAGATTGAAGCAAAGATTCCTACTTGTCAGCCAGCATGTGGGAAACCAACTCAGCCTCTCCCTGGAATAGTGAAGCGGATCATTGGAGGACGGAATGCAGAGCCAGGATTCTTCCCATGGCAAGTCCTTATTGTTGTGGAAGATCTTTCACGAGTTCCTATGAACAAATGGTTTGGTGGTGGAGCTCTTATCTCAGACTCCTGGGTACTGACAGCTGCTCACAACTTAAGATCCCAGCGTCGTGACAACACAGTGATGCCAGTTTCCAAAGAGCATGTCACCATATATTTGGGTTTGCATGATGTGCAGAGTAAGACAGATTCAGTGAACAGAACTATAGAGAAAATCATATTGCATGAAATGTTTGACCCAGAGAGTTATAACCATGACATTGCCCTAGTGAAGCTAAATGAGAAAGTTATTATGAACCAGTATGTGATGCCAGTTTGCCTGCCAGAATTTGAGCATGAGTTGGAAGGACCTCAGCCTAACACTCTAGGCCTTGTGGCAGGCTGGGGCATTTCCAGTGCTAACATCACTGTAGAGGAAGTTATCAGCTCAGACATAAGGACACACTCTGCTATCCTACAGTATGTCAAGCTTCCAGTGGTGCTTCATGCAGTGTGCAAGGAGAGCTATGAATCCCGCTCAGGAAATTATAGTGTTACAGAAAATATGTTCTGTGCTGGTTATTATGAAGGGGGGAAAGACACCTGTTTCGGGGATAGTGGAGGTGCATTTATTATGCAGGACACTGACACAAAGCGTTGGGTGGCACAAGGGTTAGTTTCTTGGGGTGGACCTGAAGAATGTGGGAGCAAGCAGGTATATGGTGTCTATACCAAAGTATCTAACTTTGTGGACTGGGTAGATGATAAACTTAAGTCCTAAACTGGCCTAAGATAAACTACGAATTATAGCTGTAACCCACAATATCAAAACCCAGAAAGTAGTCAGACAATCAAAGCTCATATTTTAACAATATTGTATAAAAGTATTTATGAATACATTAAATAATTGTTCTTTTTTTATATAGTTTTGCTTTTTAAACTGTTATTTTAACTAAAAAGTGAAGTGTTACTGCTTTCAGGAGACTGCCTAAAATACCTCAATCCTGGTATTCAAAATCAAGGCTCTGATAAGACCAACTTTGTCTTGAGCAAAATGTGCAAATAATGTACAATGTATGCAACTGTGGAATTTGATATTGCTTGCTTCAGTAGAGCCATCTTCGTGGATTTTTTTTAAGTAGTTATGAAAATGTTTCAATGTAGAATGCCTGTACCTAGCTAGCAATATGGAATCTCGCATGCATATGTATACATTCACATTTGTAGAGGCAGAATAATCTAAGTTCAAAATGAAATATCTCATGAACAGAACTGTCTAAATAAAGAAAAAAATAATATAAGCTAAGACATGTAGAACAATAATCTGATGCTATGGAGAAAAAACATTCTTAACAAATTTGGTGTTTCCAACTGAAAAAATATTTTAGCAACCAAATAGTATAATAAAGAGATTCTGTTGATAAAACAGGGAGTCTAAAGTAAAGTGATTTTTAATCAACAGCAGTTAAAAGTGTCAGTTAAACTCTACTTGAATTAAGTAATACAAAGAGGGTCTTTTTTTTAAATTAAAGGACATGTAAAGCCTACATTTTTCTGTATATTAGATGGGCATATTGTATCTTCCCCACCCAAACCACATCATTTGTACTGTATATACCCCCTCCATTTGCTATCAACATCACATTTTCCTTAAACAAATAGCATCTTTCACCGGGCGGACATTTTCCGTCTGACACATTATCAGCAAACATTGACATCTGCAAACAGAACATGTATGCTGTAAAGTTCATGCAATGCAGAATGCATGTTTACAAAGCACACAATACTTTGATAAAAGGTTCTGCTTGGGTTGAGCACTGTAATGTTTAAGCTGAGCTCAGCAGAGGTGGTTTGTGTAAGACAATAGGATCAGGCAGCTAGAGTTTCTATCTCTTCATTGACTGTGGGCTCCCTTTATTAAGAATTATGCAGTACCTCAATTTTACCTGTTTGATATCAGACATTTAACAGATCGGCCAATTTCTAACCAGGATTCCCTGGTAGATGCCTTTGGCTGTGCATATGTGCAGTAGAGTAAAATTGGTACTTAAACACTAAAAGCTGCACAGGGGCATAAATTAGGGGGCCCGTTCCTCTGAAAAAAATTTTTCATAGCTTCCTTCCATTGAAAAAGCAGAGGTAGCCTTCAGTGCACTTAAAATCATGGTTCACCCACAATTTTGCTTGTGTTGCAGGTCACCAGTGACATTCTCTGTGGTCATAGGGTCTGTCAGCTCTGTATAGTTATGCCACTGCAAGCAAACAAGCTGGCAGCATAGAATTCTGGTGTGGGGACTGAAGTAGGTAGTTATAATCTATAGGTGATTTCCAGTGATTTTGCTTTTTAATAGCAAGATTTTTTCAACCTATTTTAGCTATCAGCTAATAGCATTCCTCAGGCAGTAAAGCCACAGGCCAGTTAAGTTTAGTCTGTAACAAATCAAATCAGAATTTTAGGGTTGCCTGCCATTTCATTTATCATACAGTATGTCACTTTCACAATAAACACCATGGATGCTGCTTTTGTTCTGTGCATGGCCTAGCAATTAATTTTCTTAAATTTTTTTGGAATTTGGAAATATAGAATTTTTATTGCTGGCACACTGTGCTTTGGCACAGTAGGTCAAGCATAATATCAGCCTTGTGTGGTTTATGAAAAATATTCTATCTTTGTGAGATATATTCACATGTATATACAACATTTCATGTGTAACCAAATCCCTTCCTCAGGATCCCCCAGGAATATATACAGAAAGACAGTGCCCTAGGGCATAAAATCTACAGAACTGAAATTCAAGATACAGAGTTCAAATACAGTAGGCTCTACATTTCAGGATAACACATTATTATTAGTTTGGTGAGATTATGAGTTGTCATTGGATGATCCGTAAAGGGTTAAAGCCCTTAAGGAAACACAAAAAAGAAAAAATTAATGGTCATTTGCTTTTAAAGCAAAAATGTTACAATAAATGTGCTCATAGAATTAGAATACTGTGAAATAATGTTATTTTACTGTGCTGTTAATGTATAGTTTTGAATCTTATTTCCCTTTTAAAACACTCCTCCCAAAAATAGCCAGAGACATATGAATGCAGCTGTGGATGCAATTGTACATTTCTTTGCTGTTCTATGATTGCAAACTATTTTCCATGTTATGTTTATGTATATATTCGTGCTTATATTTTATAATAAAGATATATGAACTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein	Refseq >NP_001090874\|mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) precursor [Xenopus (Silurana) tropicalis] MRIPLLFSFFLWMLSEAEVIQLTDTFGEIRTPNFPDSYPSDSEVTWNITVPEGFRLKLYFMHFDLEPSYLCEYDYAKVETEDQVIASFCGKESTDTEQAPGKQMITSPGNFLSLTFRSDFSNEERFTGFDAHYSAIDIDECTEKNDEDLVCDHHCHNYIGGFYCSCRFGYLLHTDNRTCKVECSDNLFTQRSGLISSPDYPSSYPKSSDCRYRIELEEGFVINLHFDDNFDVEDHPEVTCPYDYLKIKTGKKEIGPLCGEKSPGRIETGSNSVQILFHSDNSGENGGWRFSYSVSGTPCPNLRPPINGKLEPSQAEYTFKDQVVISCNQGYRVLKDNVEMESFQIECRKDGTWSNQIPTCQIVDCKTPKEIENGFITYSTAENRTTFQSSFNYSCREPYYTMVPNITSVYTCDASGEWKNQETGAKFPTCQPVCGKPTRPLPGIVKRIIGGRNAEPGFFPWQVLIVVEDLSRVPMNKWFGGGALISDSWILTAAHNLRSQRRDNTVMPVSKEHVTVYLGLHDVRSKMDAVNRTIEKIILHEMFDPESYNHDIALVKLNEKVIMNQYVMPVCLPELEHELEGPQPNTLGLVAGWGISNPNITVDEIISSDMRTHSAILQYVKLPVVLHEVCKESYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFIMQDTDTKRWVAQGLVSWGGPEECGSKQVYGVYTKVSNFVDWVDDKLKS	Refseq >NP_001082340\|mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) precursor [Xenopus laevis] MRIPLLFSICLWMLSEAEVIQLTDMFGEIRTPNFPDSYPSESEVTWNITVPEGFRLKLYFMHFDLEPSYLCEYDYAKVETEDQVIATFCGKESTDKEQAPGQRIITSPGNFLSLTFRSDFSNEERFTGFDAHYSAKDIDECTEKSDEDLVCDHHCHNYIGGFYCFCRFGYLLHTDNRTCKVECSDNLFTQRSGFISSPDYPSPYPKSSNCRYRIKLEEGFVINLHFDDSFDVEDHPQVTCPYDFVKIKSGKKEFGPLCGEKSPGTIETGSNSVQILFNSDNSGENGGWRLSYSATGAPCPNLHPPINGKLEPSQSEYIFKDQVVVSCNQGYQVLKNNVEMESFQIECRKDGTWSNQIPPCQIVDCRTPKEIENGFITYPTADNHTTYQSSFNYSCREPYYIMVPNITSVYTCDSNGEWTSQEIEAKIPTCQPACGKPTQPLPGIVKRIIGGRNAEPGFFPWQVLIVVEDLSRVPMNKWFGGGALISDSWVLTAAHNLRSQRRDNTVMPVSKEHVTIYLGLHDVQSKTDSVNRTIEKIILHEMFDPESYNHDIALVKLNEKVIMNQYVMPVCLPEFEHELEGPQPNTLGLVAGWGISSANITVEEVISSDIRTHSAILQYVKLPVVLHAVCKESYESRSGNYSVTENMFCAGYYEGGKDTCFGDSGGAFIMQDTDTKRWVAQGLVSWGGPEECGSKQVYGVYTKVSNFVDWVDDKLKS

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC	Xenbase

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.64668 [+] Str.38972 Str.48843	Xl.21674
Unigene EST Profile	EST Profile	EST Profile
GEO data		GEO
Images	0 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	MASP1
mouse	MGI	Masp1	All(2) Targeted, knock Out(2)
zebrafish		masp1

Publications
First:		MASP1 (MBL-associated serine protease 1). [Immunobiology 1998]
Most recent:		Composition of the lectin pathway of complement in Gallus gallus: absence of mannan-binding lectin-associated serine protease-1 in birds. [J Immunol 2005]
		View All Papers

Functional Ontologies
GO: Molecular:		calcium ion binding chymotrypsin activity pancreatic elastase activity More[+] plasminogen activator activity proprotein convertase activity serine-type endopeptidase activity serine-type signal peptidase activity subtilase activity trypsin activity
Biological:		complement activation proteolysis
Cellular Component:		extracellular region
EC:		Serine endopeptidases
KOG:		[E] Trypsin

Reagents	tropicalis	laevis
Clones	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.38972.1.S1_at [+] Str.38972.2.S1_at Str.48843.1.S1_at StrEns.2492.1.S1_at	Xl.21674.1.S1_at
Affymetrix 2.0		Xl2.21674.1.S1_at

Symbol legend[+]