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Summary Expression Gene Literature (6) GO Terms (10) Nucleotides (129) Proteins (28) Interactants (72) Wiki
XB-GENEPAGE-987374
Gene Symbol:
sirt2

Gene Name:
sirtuin 2

Synonyms:
sir2 , sirtuin , xsirt2 ( Add synonyms , Nomenclature history )

Gene Function:
NAD-dependent histone deacetylases and class I sirtuins (SIR2 family)

Protein Function :
NAD-dependent protein deacetylase.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-987375 XB-GENE-17343217 XB-GENE-987378
Gene Symbol sirt2 sirt2.L sirt2.S
Chromosome Chr02 chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100489469
495688
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sirt2 sirt2.L sirt2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SIRT2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sirt2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sirt2 Ensembl
zebrafish
ZFIN, AGR sirt2 ZFIN Ensembl
chicken
GEISHA SIRT2 Ensembl
fruit fly
FLYBASE Sirt2 Ensembl
worm
Publications
First Cdc5 influences phosphorylation of Net1 and disassembly of the RENT complex., BMC Mol Biol 2002                
Most Recent Identifying Dysregulated Epigenetic Enzyme Activity in Castrate-Resistant Prostate Cancer Development., ACS Chem Biol 2017  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 0 term 4 terms
PANTHER sirt2
KEGG Pathways K11412
KOG [BK] NAD-dependent histone deacetylases and class I sirtuins (SIR2 family)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sirt2
ORFs sirt2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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