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Summary Expression Gene Literature (9) GO Terms (28) Nucleotides (134) Proteins (40) Interactants (144) Wiki
XB-GENEPAGE-989002
Gene Symbol:
sirt1

Gene Name:
sirtuin 1

Synonyms:
sir2l1 , sirtuin , xsirt1 ( Add synonyms , Nomenclature history )

Gene Function:
Sirtuin 5 and related class III sirtuins (SIR2 family)

Protein Function :


InterPro :
DHS-like NAD/FAD-binding dom , Sirtuin cat small dom sf , Sirtuin , Ssirtuin cat dom [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-989003 XB-GENE-989007 XB-GENE-17335004
Gene Symbol sirt1 sirt1.L sirt1.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100145679
100036963
108697451
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sirt1 sirt1.L sirt1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SIRT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sirt1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sirt1 Ensembl
zebrafish
ZFIN, AGR sirt1 ZFIN Ensembl
chicken
GEISHA SIRT1 Ensembl
fruit fly
FLYBASE Sirt1 Ensembl
worm
Publications
First Facile synthesis of site-specifically acetylated and methylated histone proteins: reagents for evaluation of the histone code hypothesis., Proc Natl Acad Sci U S A 2003  
Most Recent Identifying Dysregulated Epigenetic Enzyme Activity in Castrate-Resistant Prostate Cancer Development., ACS Chem Biol 2017  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 2 terms 2 terms
PANTHER sirt1
KEGG Pathways K11411 K11411 K11411
KOG [BK] Sirtuin 5 and related class III sirtuins (SIR2 family)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sirt1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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