[provisional- machine annotated only] Gene Symbol: frrs1 [Predicted: Source is Human Entrez Gene] Gene Name: ferric-chelate reductase 1 [Predicted: Source is Human Entrez Gene] Add Xenopus synonyms Gene Function: Predicted membrane protein, contains DoH and Cytochrome b-561/ferric reductase transmembrane domains Interactants:

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002936961|PREDICTED: Xenopus (Silurana) tropicalis putative ferric-chelate reductase 1-like (LOC100497064), mRNA GTTGGGTAATGAGCTGCATAGGGCAAGGTAGAAATCGCTGTCTTTGAATTCTTCATGCAGGATAGTAAGATGATTCCTTTGGTTATTTTTCTCATTTTCCTTTGCACTTGTGCATTGACCCCAGTGACTGGGTATCCCAGTGGTAAAGTGACTTCTGCCTGCAGATCTATGCGCCCTGACCATGGTCATGCCCCACAAGCTGAGCCCATTCACAGTATTAATGTGGACAAAACCATTTTTAACCCAGGCGATCGCATCAAAGTCACCTTGTCAGGATCTCGCTTCAATGGATTTTTGGTTCAAGCTCGTGATGTGGAGAACCTGGATGGCAGTGCTGTGGGGTCATTTGCTTTAATTGATGAGAGGGTTTCCCAGCTTTTGACTTGTGGTGGCATCCAGAATTCAGCTGTCAGTCACACCAGCAAGGAGAGAAAGCTCCAAGTGGAGTTCTTTTGGATTGCTCCGGCCAACAGCCCAAAGCATGTTCAGTTTCTGGCTACAGTAGTCGAAAAATATAAAATCTATTGGGTGAAGATTGCCGGCCCTATTATATCACAGCCCAACACACCACCTATCCCATCTAAAAATCATAGTAGCATGATACCAGTGGTACCACCATCCCTTCATAAACGTTTTAGCCCAGCAGGCTGTGGAAGCACCAAGTTCTGCATCAGAAATCCAGTCTCCTGTGACCCAGAGCATAATCCTAAGTGCTTCTTCCTGTCCTTCAGAAAAGATGGCCAGTCTGTACTGGTTGAGATGAGTGGACCAGGGCAAGGCTACATCTCTTTTGCCTTATCATATGATCATTGGATGGGGGATGATGATGCCTACTTGTGTGTCAAAGAAGACCAAGGAGTTCAAATAAATCCAGCTTACATCAGGGGGCGATCTCACCCTGAAGTGTCATCTCCGGATGTTCTAAGGGATGTGGCATGGCGGCTGGAAGATGGAGTCATTCAGTGCTCCTTTAAGAGAAACATCCAAATTCCCGCGTCCAAAGAGCGGTTTGACCTGGGTGGCAGTTACTACATCTTTCTTGCTGATGGTGATGCAAAGGATGGTCTCCTTCTCCGACACCAGCGACAACCGCTTATGACAAACAGAATGTATAATATATCTGGCTTTCCTGAAGATGTGGGGGGCTCACGGTCCCCACTCATAATAAAATTTCACGGTGCTATGATGTTCGTTGCATGGATGACTACTGTGAGCATTGGGGTTATTATTGCCCGATTCTTCAAACCAGTGTGGCCTACTTCATCTTTGTTTGGTGAAAAAATTTGGTTCCAGATTCACCGCTGTCTTATGATTACTACAGTGATTCTAACAGCCATTGCTTTTGTATTGCCCTTTATATACAGAGGATACTTTAGTAAACGAGCAGGTTATCATCCCCATCTGGGGGTTACTGTGATGATTTTGACTGTGCTCCAGCCTGTTTTGGCTGTTTTCAGACCTCCACCTCAAACACCCAGGAGAGGGATATTTAACTGGACTCATTGGGCTACTGGTACTGCTGCCAGGATTATAGCAGTGACTGCAATGTTCATTGGAATGGATTTGCAAGCACTGGATCTTCCTGATCCATGGGACACCTACACCATGGTTGGCTTTGTACTGTGGCACGTTTTTGTAGATCTCCTGCTTGAGGCTCATGGTTTCTGTCTCTTAAAGAAAGAGTATATTTCAAAGCTGCCCTGTCACCTGCAAGCTCTACACCAGTATGGACTATTTATTGGTGGATCTAAACAGTCAGACCCTCAAAGTGCCAAGGTTGTTTTGGTTCCCTCTGTACTGGAGGGACATGCAGGACATTCAGCTAAAACAATGGAAGAGGATCAAGTAGGAATTTTGAACTCATCTCCTGATGAAGCAGAGGGCCACACCTTTAAGAAGATTGTTCTGACAGTGTATATATGTGGAAACCTTGCATTTCTCATAACCTTCCTAGCTGCAATCAACCAAATTTGAAATCCATGTAGGACTATGCCCTGTATTGCTGCCTTGGCCTGGCAAAGAGTCAGCCTTGAATCTCATTTTAGGTCATTCCTGCAAGGACTCCTTCTCCTGGTGGTAAAGACTGGTAACCAGTACCTTGAAATAACACCAGTGCGCCTCTGTAGGATTATTTATATCTCAAGGTGTGAAGTCTGATTGCTTAGGTAAAGGAATACCTAGTGTTAATTAATTATAGAGTCATTCTTGACTCTGTCCATTCTGCAGATGAATTTTTGACATTGCAGTGCCTTTTGGAGTCCACAGTTCAGAATACATTGGAGAACTTTATTTGTTATGCTGAGAATATAAACACTGGACCAATATATTTCTTATTAAGTAGGTGCCTGAATTATTTTTCTCATATCTTTATATAATTTATATATATAAATTGTGTATTGCGCTATTTAAACAGGACTTAAAATGTGACCTTTTATTAAAAGTTCTGCTTTGCAAAATA	Refseq >NM_001091659|Xenopus laevis ferric-chelate reductase 1 (frrs1), mRNA GTAATTAGTTTGCCTGGCACTGAAGAGGCGCTGGGGAATGAGGTGAGCGGTGCGGAGGTGAAGTCGCTGTTTTAGATCTCCATACGAGCAAGTACGATGAATCCGTTGGGCCTTTTTCTCATTTACCTTTACACTTGTGCACTGACCCCAGTGTCTGGTTATCCCAATGGTAAAGTGACTTCTGCCTGCAGATCTATGCGCCCTGACCATGGCCATGCTCCACAATCTGAGCCCATTCACAGCATTAATGTAGAAAAAACTATTTTTAAACCAGGAGATCGCATTAAAGTCACCTTGTCTGGATCTCGCTTTGATGGATTTCTGGTTCAAGCTCGTGATGCAGAGAACTTGGAAGGCAGTGCTGTGGGATCATTTTCTTTAACTGATGAGAGGATTTCCCAGCTTTTGACTTGTGATGGCATCCAGAATTCAGCTGTCAGTCACACCAGCAAGGAGAGAAAGCTTCAAGTTGAGTTATTTTGGATTGCTCCTGCCAACAGCCCAAAGCATATTCAGTTTCTAGCTACAGTAGTTGAAAAATATAAAATCTATTGGGTGAAGATTCCCGGCCCTATTATATCACAGCCCAAAGCACCATCAATTGCACCTAAGATTCCCAGTAGCACGATACCAGTGGTACCGCCACCATCTTTATCACTTCATAAACGTTTTAATTCAGCAGGCTGTGGCAGCAGTAAGTTCTGCATCCGAAATCCAGTCTCCTGTGACCCAGAGCATAATCCTGAGTGCTTCTTCCTGTCCTTCAGAAAAGATGGCCAATCTGTACTAGTCGAGATGAGTGGACCAGGACAAGGCTATATTTCTTTTGCCTTATCACATGATCAGTGGATGGGGGATGATGATGCCTACTTGTGTGTCAAAGAAGACGATGGTGTTCAGATAAATCCAGCCTACATCAGGGGACGATCTCACCCTGAAGTGTCATCTATGGATGTTCTTAGGGATGTTGCATGGCGGCTGGAAGATGGTGTAATTCAGTGTTCTTTTAGAAGAAACATCCAAATTCCTATCCCTAAAGAACGATTTGACCTGGGTCGGAGTTACTTCATTTTTCTTGCTGATGGTGATGCAAAGGATGGTCTCCTTTACCGACACCACAGGCAACCTCTAATGACAAACCGAAAGTATTGTATCACTGACTTTCCTGAAGATGTGGGGGGATCGCGATCCCCACTTATAATAAAGTTACACGGTGCTATGATGTTTATTGCGTGGATGACTACTGTGAGCATTGGGGTCATTATTGCCCGATTCTTCAAACCAGTCTGGCCTACTTCGTCTTTGTTTGGTGAAAAAATTTGGTTCCAGATTCACCGCTGCCTTATGATCACTACAGTGTTTCTAACAGTTGTTGCTTTTGTATTGCCTTTTATATACAGAGGATACTTTAGTAAACGTGCAGGTTATCATCCCCATCTGGGGGTCACTGTGATGATTTTGACAGTTCTTCAACCTGTTTTGGCAGTTTTCAGACCTCCACCTCAAACACATAGGAGAGGGATATTTAACTGGACTCATTGGGCTACTGGTACTGCTGCCAGGATTATAGCAGTGGCTGCAATGTTTCTTGGGATGGATTTACAAGCATTGGACCTTCCTGATCCATGGGACACCTACACCATGATTGGCTTTGTACTATGGCACGTTTTTGTAGATCTCCTGCTTGAGGCTCATGGGTTCTGTCTCTTAAAGAAAGCTAAAACAATGGAAGAGGATCAAATAGGAATTTTGAACTCGTCCCCCGATGAAGCAGAGGGCCATACCTTTAAGAAGATTGTGATGACGGTCTATATATGTGGAAACCTTGCATTTCTCATAACCTTCCTAGCTGCAATCAACCAACTTTGAAGTCCATGTAGGACTCTGCCCTGTATTGCTGCTTTGACTTGGCAAGAAGTGACCGCTTTGAATCTCCGTTTAATTCATTCTTGCAACGACTGCTTCTCCTGCTGCTATAGACTGGTAACCACTACCCTGAAATAACACCATGTGCCTTGGTAGGATCTGATTGTTCAGATAAAAGAAGACCTAGGGGGCCTATTTGTCATGCCGCGTAAACCTCACAGGTGATGTTACCCATAGCAACCAAATAGCAATTGGATTTTAACACTCGCCTACATGTTAGGAAGCAAAAGCAAAGATCTGATTGGTTGCTATGGGTAAGACCACCAGTGATGTTTTTCTCCTCTGTTTGATAAATAGGCCCAACATGTTAATTAATTATAGAGGTATTTTTTTTATTCTGTCCATTCGGCAGCTGAACTCAGCTTTGTGAGTTGACTGCTTAGAATACATCAGAGAATATTTGTTATGCTGAGAGTATAAACACTGGACCAATTGCCACAACAGTGTCAAAAATATATTTCTTGTTCTTACGGAGGTGCCTAAAATGTTTTTTTTTCCTTCTTATATATTTATAACATTTAAATATGAATTGTCTATTGAGCTATTTAAACAGAACTTAAAATGTTGCCTTTTATTAAAGGTTCTCCTTTGCAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002937007|PREDICTED: putative ferric-chelate reductase 1-like [Xenopus (Silurana) tropicalis] MQDSKMIPLVIFLIFLCTCALTPVTGYPSGKVTSACRSMRPDHGHAPQAEPIHSINVDKTIFNPGDRIKVTLSGSRFNGFLVQARDVENLDGSAVGSFALIDERVSQLLTCGGIQNSAVSHTSKERKLQVEFFWIAPANSPKHVQFLATVVEKYKIYWVKIAGPIISQPNTPPIPSKNHSSMIPVVPPSLHKRFSPAGCGSTKFCIRNPVSCDPEHNPKCFFLSFRKDGQSVLVEMSGPGQGYISFALSYDHWMGDDDAYLCVKEDQGVQINPAYIRGRSHPEVSSPDVLRDVAWRLEDGVIQCSFKRNIQIPASKERFDLGGSYYIFLADGDAKDGLLLRHQRQPLMTNRMYNISGFPEDVGGSRSPLIIKFHGAMMFVAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVILTAIAFVLPFIYRGYFSKRAGYHPHLGVTVMILTVLQPVLAVFRPPPQTPRRGIFNWTHWATGTAARIIAVTAMFIGMDLQALDLPDPWDTYTMVGFVLWHVFVDLLLEAHGFCLLKKEYISKLPCHLQALHQYGLFIGGSKQSDPQSAKVVLVPSVLEGHAGHSAKTMEEDQVGILNSSPDEAEGHTFKKIVLTVYICGNLAFLITFLAAINQI	Refseq >NP_001085128|putative ferric-chelate reductase 1 precursor [Xenopus laevis] MNPLGLFLIYLYTCALTPVSGYPNGKVTSACRSMRPDHGHAPQSEPIHSINVEKTIFKPGDRIKVTLSGSRFDGFLVQARDAENLEGSAVGSFSLTDERISQLLTCDGIQNSAVSHTSKERKLQVELFWIAPANSPKHIQFLATVVEKYKIYWVKIPGPIISQPKAPSIAPKIPSSTIPVVPPPSLSLHKRFNSAGCGSSKFCIRNPVSCDPEHNPECFFLSFRKDGQSVLVEMSGPGQGYISFALSHDQWMGDDDAYLCVKEDDGVQINPAYIRGRSHPEVSSMDVLRDVAWRLEDGVIQCSFRRNIQIPIPKERFDLGRSYFIFLADGDAKDGLLYRHHRQPLMTNRKYCITDFPEDVGGSRSPLIIKLHGAMMFIAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVFLTVVAFVLPFIYRGYFSKRAGYHPHLGVTVMILTVLQPVLAVFRPPPQTHRRGIFNWTHWATGTAARIIAVAAMFLGMDLQALDLPDPWDTYTMIGFVLWHVFVDLLLEAHGFCLLKKAKTMEEDQIGILNSSPDEAEGHTFKKIVMTVYICGNLAFLITFLAAINQL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.14076	Xl.25809
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	FRRS1
mouse		MGI	Frrs1	All(2) Targeted, other(2)
zebrafish

Publications
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Most recent:
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Functional Ontologies
GO: Molecular:		dopamine beta-monooxygenase activity
Biological:		catecholamine metabolic process
Cellular Component:
EC:
KOG:		[T] Predicted membrane protein, contains DoH and Cytochrome b-561/ferric reductase transmembrane domains

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.14076.1.A1_at	Xl.25809.1.A1_at
Affymetrix 2.0			Xl2.25809.1.S1_at

Symbol legend[+]

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