Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (35) GO Terms (15) Nucleotides (341) Proteins (64) Interactants (424) Wiki
XB-GENEPAGE-990505
Gene Symbol:
kdm2b

Gene Name:
lysine (K)-specific demethylase 2B

Synonyms:
fbxl10 , jhdm1b ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-3...[+]



Interactants:
Loading ...

Diseases: 


External Links:
1/3
 
Xenbase Gene ID XB-GENE-990506 XB-GENE-990512 XB-GENE-17333167
Gene Symbol kdm2b kdm2b.L kdm2b.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448624
444267
108707160
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kdm2b kdm2b.L kdm2b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KDM2B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kdm2b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kdm2b Ensembl
zebrafish
LOC100536129 Ensembl
chicken
GEISHA KDM2B Ensembl
fruit fly
worm
Publications
First KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands., Elife 2012                        
Most Recent Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin., Dev Cell 2015                                    
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 9 terms 0 term
PANTHER kdm2b
KEGG Pathways
KOG [B] F-box protein JEMMA and related proteins with JmjC, PHD, F-box and LRR domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kdm2b
Morpholinos kdm2b MO1 kdm2b MO1 kdm2b MO1
ORFs kdm2b ORF1 kdm2b.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list