Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (12) GO Terms (12) Nucleotides (57) Proteins (33) Interactants (139) Wiki
XB-GENEPAGE-992091
Gene Symbol:
dcx

Gene Name:
doublecortin

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Microtubule assembly protein Doublecortin and related proteins, contain DCX domain

Protein Function :


InterPro :
Ez/rad/moesin-like , Ubiquitin-like domsf , FERM CS , FERM/acyl-CoA-bd prot sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
lissencephaly [+]

OMIM:
LISSENCEPHALY, X-LINKED, 1; LISX1

External Links:
 
Xenbase Gene ID XB-GENE-992092 XB-GENE-17344744 XB-GENE-17344745
Gene Symbol dcx dcx.L dcx.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100493401
108698401
108700105
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dcx dcx.L dcx.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DCX OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dcx MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dcx Ensembl
zebrafish
chicken
GEISHA DCX Ensembl
fruit fly
worm
Publications
First LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome., Neuron 2000    
Most Recent Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis., Neural Dev 2021                                
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 3 terms 3 terms
PANTHER dcx
KEGG Pathways K16579 K16579 K16579
KOG [DZ] Microtubule assembly protein Doublecortin and related proteins, contain DCX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dcx
Antibodies Dcx Ab3 Dcx Ab3 Dcx Ab3
Clones Horizon Horizon Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info