Gene Symbol: crh Gene Name: corticotropin releasing hormone Synonyms: crf, corticotropin-releasing factor, corticoliberin Add Xenopus synonyms Gene Function: hormone involved in stress response Interactants: avp(5) , npy(5) , crhbp(4) , crhr1.2(4) , sst(4) , trh(4) , cck(3) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		NCBI Nucleotide >XM_002940563|PREDICTED: Xenopus (Silurana) tropicalis corticoliberin-like (LOC100485597), mRNA ATGAAGTTCCAGCTGTGGGTGTCTACAGGAATCCTACTGGTCTCTCTCCTCCCCTGCCATGAGTGCCGAGCTTTCAGTAAATCCCCAGCATCTTCTCCTGGAGCTCCCCTGCCTGCTCTGTCCAATTCCCAGCCCTTTCTACTTCGCATGGGAGAAGAGTATTTCCTCCGGCTAGGCAATCTCCATAAGTATTCCCCAAGCTCGTTTGCAGCCAGCCGGCTTCCCGAGGCATCTGGCGGTAACTTTGTGAGGGCTGTACAGCAGCAACTGCAGGCTCAGCAGTGGAGCAGCCAGCCAGGGCTGAGAGCTGCAGCTTTGGATGGAGCAGACAGCCCTTACAGTGCTCAGGAAGAGCCCACAGAAAGAGCAAAGCGTGCAGAAGAGCCTCCCATTTCCCTGGATCTGACTTTTCACTTGCTCCGTGAAGTCTTAGAAATGGCAAGAGCTGAGCAAATAGCCCAGCAAGCCCACAGCAACAGGAAACTCATGGACATCATTGGGAAATAG	Refseq >NM_001172210|Xenopus laevis corticotropin releasing hormone (crh-a), mRNA CTCTCCTCACTGCCCTTTTCCTTGTGCTGTTCCCATCCATTCTAAGGATCCCTGTGCATCAGTTTTTTCTGATCTTCGATCTTTGGAGTGAATATGAAGTTCCAGCTGTGGGTGTCTACAGGAATCCTACTGGTGTCTCTCCTCCCCTGCCATGAGTGCCGAGCTTTCATTAAATCCCCAGCATCTTCTCCTGGAGCTCTCCTGCCTGCTCTGTCCAATTCCCAGCCCTTTTTACTGCGAATGGGAGAAGAGTATTTCCTACGTCTAGGTAATCTCCATAAGCATTCCCCAGGCTCGTTTCCTGAGGCATCTGCTGGTAACTTTGTAAGAGCTGTACAGCAACTGCAGGCTCAGCAGTGGAGCAGCCAGCCAGGGATGAGAGCGGCATCTTTGGATGGAGCAGACAGCCCTTACAGTGCTCAGGAAGATCCCACAGAAAAAGCAAAGCGTGCAGAAGAGCCTCCCATTTCCCTGGATCTGACTTTTCACTTGCTCCGTGAAGTCTTAGAAATGGCAAGAGCTGAGCAAATAGCCCAGCAAGCCCACAGCAACAGGAAACTCATGGACATCATTGGGAAATAG		Refseq >NM_001172209|Xenopus laevis corticotropin releasing hormone (crh-b), mRNA TTTAAGGATCCCCTGTGCTTCAGTTTTATCTGAGCTTCAATCTTTGGAGTGTAATATGAAGTTCCAGCTGTGGGTGTCTACAGGAATCCTACTGGTGTCTCTCCTCCCCTGTCATGAGTGCCGAGCTCTCAGTAAATCCCCAGCATCTTCTCCTGGAGCTCCCCTGCCTGCTCTGTCCAATTCCCAGCCCTTTTTACTCCGCATGGGAGAAGAGTATTTCCTACGCCTAGGCAATATCCAGAAGTATTCCCCAAGCTTGATTGCAGCCAACCAGCTTCCCGAGGCATCTGCCGGTAACTTCGTGAGAGCTGTACAGCAACTGCAGGCTCAGCAGTGGAGCAGCCAGCCAGGGCAGAGAGCTGCAGCTTTGGATGGAGCAGACAGCCCTTACAGTGCTCAGGAAGAGCCCACAGAAAAAGCAAGGCGTGCAGAAGAGCCTCCCATTTCCCTGGATCTGACTTTTCACTTGCTCCGTGAAGTCTTAGAAATGGCAAGAGCTGAGCAAATAGCCCAGCAAGCTCACAGCAACCGGAAACTCATGGACATCATTGGAAAATAG
Protein		NCBI Protein >XP_002940609|PREDICTED: corticoliberin-like [Xenopus (Silurana) tropicalis] MKFQLWVSTGILLVSLLPCHECRAFSKSPASSPGAPLPALSNSQPFLLRMGEEYFLRLGNLHKYSPSSFAASRLPEASGGNFVRAVQQQLQAQQWSSQPGLRAAALDGADSPYSAQEEPTERAKRAEEPPISLDLTFHLLREVLEMARAEQIAQQAHSNRKLMDIIGK	Refseq >NP_001165681|corticoliberin [Xenopus laevis] MKFQLWVSTGILLVSLLPCHECRAFIKSPASSPGALLPALSNSQPFLLRMGEEYFLRLGNLHKHSPGSFPEASAGNFVRAVQQLQAQQWSSQPGMRAASLDGADSPYSAQEDPTEKAKRAEEPPISLDLTFHLLREVLEMARAEQIAQQAHSNRKLMDIIGK UniProtKB		Refseq >NP_001165680|corticotropin releasing hormone [Xenopus laevis] MKFQLWVSTGILLVSLLPCHECRALSKSPASSPGAPLPALSNSQPFLLRMGEEYFLRLGNIQKYSPSLIAANQLPEASAGNFVRAVQQLQAQQWSSQPGQRAAALDGADSPYSAQEEPTEKARRAEEPPISLDLTFHLLREVLEMARAEQIAQQAHSNRKLMDIIGK

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene			Xl.85742		Xl.85738
Unigene EST Profile			EST Profile		EST Profile
GEO data			GEO		GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CRH	OMIM:201400
mouse		MGI	Crh	All(6) Targeted, knock Out(1) Targeted, other(4)
zebrafish		ZFIN	crhb	15 Lines(s)

Publications
First:		Evidence for corticotropin releasing factor (CRF) synthesis in the preoptic nucleus of Xenopus laevis tadpoles: a preliminary report based on lesion experiments. [Cell Tissue Res 1976]
Most recent:		An intrinsic CRF signaling system within the optic tectum. [Gen Comp Endocrinol 2013]
		View All Papers

Functional Ontologies
GO: Molecular:		hormone activity
Biological:
Cellular Component:		extracellular region
EC:
KOG:

Reagents		tropicalis	laevis a		laevis b
Clones			open biosystems		open biosystems
			geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.5234.1.S1_s_at
Affymetrix 2.0

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