Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (20) GO Terms (24) Nucleotides (220) Proteins (45) Interactants (169) Wiki
XB-GENEPAGE-996935
Gene Symbol:
eps8

Gene Name:
epidermal growth factor receptor pathway substrate 8

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Epidermal growth factor receptor kinase substrate

Protein Function :
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
autosomal recessive nonsyndromic deafness [+]

OMIM:
DEAFNESS, AUTOSOMAL RECESSIVE 102; DFNB102

External Links:
 
Xenbase Gene ID XB-GENE-996936 XB-GENE-996941 XB-GENE-17345291
Gene Symbol eps8 eps8.L eps8.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 779963
414529
108712510
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine eps8 eps8.L eps8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EPS8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Eps8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Eps8 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR eps8a eps8b ZFIN Ensembl
chicken
GEISHA EPS8 Ensembl
fruit fly
worm
Publications
First Regulation of actin cytoskeleton architecture by Eps8 and Abi1., BMC Cell Biol 2005                  
Most Recent Concomitant exposure to benzo[a]pyrene and triclosan at environmentally relevant concentrations induces metabolic syndrome with multigenerational consequences in Silurana (Xenopus) tropicalis., Sci Total Environ 2019  
All View All Papers 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 24 terms 5 terms 5 terms
PANTHER eps8
KEGG Pathways K17277 K17277 K17277
KOG [T] Epidermal growth factor receptor kinase substrate
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks eps8
Antibodies Eps8 Ab1 Eps8 Ab1
ORFs eps8 ORF1 eps8.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list