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Summary Expression Gene Literature (104) GO Terms (11) Nucleotides (228) Proteins (35) Interactants (343) Wiki
XB-GENEPAGE-999973

Gene Symbol: mcm2

Gene Name: minichromosome maintenance complex component 2

Synonyms: XMcm2 , bm28 , ccnl1 , cdcl1 , cdc19 , mitotin ( Add synonyms , Nomenclature history )

Gene Function: DNA replication licensing factor, MCM2 component

Protein Function :
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The a...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: DEAFNESS, AUTOSOMAL DOMINANT 70; DFNA70

 
Xenbase Gene ID XB-GENE-999974 XB-GENE-999979 XB-GENE-17342436
Gene Symbol mcm2 mcm2.L mcm2.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL TrEMBL Swiss-Prot RefSeq Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine mcm2 mcm2.L mcm2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards MCM2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Mcm2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR mcm2 ZFIN Ensembl
chicken
GEISHA MCM2 Ensembl
fruit fly
FLYBASE Mcm2 Ensembl
worm
WORMBASE
Publications
First Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication., Nucleic Acids Res 1992  
Most Recent RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR., Cell Cycle 2019                
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 0 term 8 terms
PANTHER mcm2
KEGG Pathways K02540 K02540 K02540
KOG [L] DNA replication licensing factor, MCM2 component
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Mcm2 Ab1 , Mcm2 Ab2 , Mcm2 Ab3 Mcm2 Ab1 , Mcm2 Ab2 , Mcm2 Ab3 Mcm2 Ab3
ORF mcm2.L ORF1
Affymetrix 1.0 Str.1626.1.S1_at Xl.382.1.S1_at
Affymetrix 2.0 Xl2.382.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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