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Summary Expression Gene Literature (67) GO Terms (21) Nucleotides (54) Proteins (28) Interactants (321) Wiki
XB-GENEPAGE-486950
Gene Symbol:
nkx2-6

Gene Name:
NK2 homeobox 6

Synonyms:
nkx2.6 , Xnkx2-10 , tix ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
double outlet right ventricle

OMIM:
CONOTRUNCAL HEART MALFORMATIONS; CTHM

External Links:
 
Xenbase Gene ID XB-GENE-486951 XB-GENE-865660 XB-GENE-17340944
Gene Symbol nkx2-6 nkx2-6.L nkx2-6.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100038094
373736
108712717
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine nkx2-6 nkx2-6.L nkx2-6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NKX2-6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nkx2-6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nkx2-6 Ensembl
zebrafish
chicken
GEISHA NKX2-6 Ensembl
fruit fly
worm
Publications
First Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes in cardiovascular development., Dev Genet 1998  
Most Recent Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Dev Biol 2017                            
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 5 terms 5 terms
PANTHER nkx2-6
KEGG Pathways K09346 [+] K09346 K09346
KOG [K] Transcription factor tinman/NKX2-3, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks nkx2-6
Morpholinos nkx2-6 MO1 nkx2-6 MO1 nkx2-6 MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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