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Summary Expression Gene Literature (21) GO Terms (28) Nucleotides (93) Proteins (41) Interactants (325) Wiki
XB-GENEPAGE-491113
Gene Symbol:
dicer1

Gene Name:
dicer 1, ribonuclease III

Synonyms:
dicer , dcr1 , herna ( Add synonyms , Nomenclature history )

Gene Function:
double-strand-specific ribonuclease

Protein Function :
Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs ...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
multinodular goiter [+]

OMIM:
GOITER, MULTINODULAR 1, WITH OR WITHOUT SERTOLI-LEYDIG CELL TUMORS; MNG1 [+]

External Links:
1/4
 
Xenbase Gene ID XB-GENE-491114 XB-GENE-17331064 XB-GENE-6460379
Gene Symbol dicer1 dicer1.L dicer1.S
Chromosome Chr08 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100170154
108698734
100316917
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dicer1 dicer1.L dicer1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DICER1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dicer1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dicer1 Ensembl
zebrafish
ZFIN, AGR dicer1 ZFIN Ensembl
chicken
GEISHA DICER1 Ensembl
fruit fly
worm
Publications
First Exonucleolytic degradation of double-stranded RNA by an activity in Xenopus laevis germinal vesicles., Proc Natl Acad Sci U S A 2003  
Most Recent De novo transcription of multiple Hox cluster genes takes place simultaneously in early Xenopus tropicalis embryos., Biol Open 2019                                    
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 5 terms 6 terms
PANTHER dicer1
KEGG Pathways K11592 K11592 K11592
KOG [A] dsRNA-specific nuclease Dicer and related ribonucleases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dicer1
Antibodies Dicer1 Ab1 Dicer1 Ab1 Dicer1 Ab1
Morpholinos dicer1 MO1 , dicer1 MO2 , dicer1 MO3 , dicer1 MO4 , dicer1 MO5 dicer1 MO1 , dicer1 MO2 , dicer1 MO3 , dicer1 MO4 , dicer1 MO5 dicer1 MO1 , dicer1 MO2 , dicer1 MO3 , dicer1 MO4 , dicer1 MO5
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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