ccnb1.2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (365)

Nucleotides (1062)

Interactants (192)

XB-GENEPAGE-5736421

[provisional- machine annotated only] Gene Symbol: ccnb1.2 [Predicted: Source is Human Entrez Gene] Gene Name: cyclin B1 [Predicted: Source is Human Entrez Gene] Synonyms: ccnb, cyclin B Add Xenopus synonyms Gene Function: cell cycle regulator Interactants: cdk1(285) , pold1(198) , mapk1(72) , cdc25c(59) , mos(53) , rasgrf1(46) , ccnb1(38) View All	1/4

XB-GENE-5736422

XB-GENE-5736929

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_203790\|Xenopus (Silurana) tropicalis cyclin B1 (ccnb1.2), mRNA GAGGTTTGTAGTGAATCAGTTGCCGTTACCAGTTTGGAAAAATGTCGCTGCGTATCACCAGAAACATGATGGCAAATGCAGAAAACAATGTGAAAACCACTGTAGCTGGAAAGAGGGTTGTTGCAACCAAACCAGTTTTGAGGCCTCGTACAGCTTTGGGAGACATAGGAAACAAGGCCGAGCTAAAAGTTCCAGCAAAAAAGGAACTGAAGCCAGCAGTAAAAGCTATCAAGAAGGTAAAACCTGTGGACAAAGTGTTGGAGCCCCTGAAAGTTAGAGAAGAGAATGTTTGCCCCAAACCTGCTCAGGTTGAACCTAGCTCACCAAGCCCAATGGAAACATCTGGTTGCCTCCCTGATGAGCTCTGCCAGGCCTTCTCTGATGTCTTGATTCAAGTTAAAGATGTTGATGCTGATGATGATGGCAATCCAATGCTGTGCAGTGAATATGTGAAGGACATTTACTGTTACCTGAGGAGCCTGGAGAATGCACAAGCAGTCAGACAAAACTACCTACATGGACAGGAAGTCACAGGCAACATGCGTGCCATATTGATTGACTGGCTGGTCCAGGTGCAAATGAAATTTCGTCTGCTGCAGGAGACTATGTTCATGACTGTTGGCATAATTGATCGCTTTCTGCAGGACCATCCAGTTCCTAAAAACCAACTGCAGCTTGTGGGGGTCACAGCTATGTTCCTTGCTGCTAAATATGAAGAGATGTACCCACCAGAAATCGGAGACTTTACATTTGTAACTGATCACACATACACAAAGGCTCAAATTAGGGACATGGAAATGAAGGTGCTTCGGGTGCTTAAGTTTGCAATAGGCCGACCATTACCTCTGCACTTTCTTCGGAGAGCTTCTAAGATTGGAGAGGTGACTGCTGAACAGCACAGTTTGGCTAAATATTTAATGGAACTTGTAATGGTGGATTATGATATGGTGCATTACTCGCCTTCCCAAATAGCAGCTGCTGCCTCTTGCTTGTCTCTTAAAATCTTGAATACGGGTGAATGGACACCAACAATGCATCATTATATGGCTTACTTTGAAGATGATCTTGTCCCTGTTATGCAACATATGGCCAAGAACATCATTAAGGTGAACAAGGGACTGACCAAACACCTGACTGTTAAGAACAAATATGCCAGCAGCAAACAAATGAAGATCAGCATGATCCCCCAGCTGAGATCAGATGTTGTTGTGGAATTGGCCCGCCCACTCATGTGATGGACTGGTGTGAATTATAACTGGATTGTTTGGCACCATGTGCTTCTGTAAATAGTGTATTTGTTTTACTTTGTGTTTTTAATAAAGCTCATTTTAACATTTGCCCAAAACAAAAAAAAAAAAAAAAAAA	Refseq >NM_001087797\|Xenopus laevis cyclin B1 (ccnb1.2), mRNA CCACTTAGTGAGACGTCTCTTTCAGACTGGGGGGCTGCAGTGTGACTTGTGGGTACAAATAGTAAAGCTGACTGCAGGTTTGCGCTTGAGAAAATGTCGCTACGAGTCACCAGAAACATGCTGGCAAATGCAGAAAACAATGTGAAAACCACTTTGGCTGGAAAGAGGGTTGTTGCTACCAAACCAGGGTTGAGACCTCGTACAGCCTTGGGAGACATTGGAAACAAGGCAGAGGTGAAAGTGCCAACAAAAAAGGAATTAAAGCCAGCAGTAAAAGCTGCCAAGAAGGCAAAACCTGTTGACAAATTGTTGGAGCCTCTTAAAGTGATAGAAGAGAATGTTTGCCCTAAACCTGCTCAGGTTGAACCCAGCTCACCAAGCCCAATGGAAACATCTGGTTGCCTCCCTGATGAGCTCTGCCAGGCTTTCTCTGATGTCCTCATTCACGTTAAAGATGTTGATGCTGATGATGATGGCAACCCAATGCTGTGCAGTGAATATGTCAAGGACATTTATGCTTACCTGAGGAGCCTTGAGGATGCACAAGCAGTCAGACAAAACTACCTTCATGGACAGGAAGTCACAGGCAACATGCGTGCCATTTTGATTGACTGGCTGGTCCAGGTGCAAATGAAATTCCGTCTACTGCAGGAGACAATGTTCATGACTGTTGGCATAATTGACCGCTTTCTGCAGGAACATCCAGTTCCCAAAAACCAGCTACAGCTTGTGGGGGTCACGGCTATGTTCCTTGCTGCTAAATATGAAGAGATGTACCCACCAGAAATTGGAGACTTTACATTTGTAACTGATCACACATACACAAAGGCTCAAATTCGGGACATGGAAATGAAGATACTTAGGGTGCTAAAGTTTGCAATTGGCCGACCCTTACCCCTGCACTTTCTTCGGAGAGCTTCTAAAATTGGAGAGGTAACTGCTGAACAGCATAGTTTAGCCAAATATTTGATGGAACTTGTGATGGTGGATTATGATATGGTACATTTCACGCCTTCCCAAATAGCAGCTGCTTCCTCCTGCTTGTCTCTCAAAATCTTAAATGCAGGTGACTGGACCCCAACACTCCATCACTATATGGCTTACTCTGAAGAAGATCTAGTCCCTGTTATGCAGCATATGGCCAAGAACATCATCAAGGTGAACAAAGGACTAACCAAGCATCTGACTGTTAAGAACAAGTATGCTAGCAGCAAACAAATGAAGATCAGCACGATTCCACAGCTGAGGTCAGATGTTGTTGTGGAAATGGCCCGCCCACTCATGTGAAGGACTACGTGGCATTCCAATTGTGTATTGTTGGCACCATGTGCTTCTGTAAATAGTGTATTGTGTTTTTAATGTTTTACTGGTTTTAATAAAGCTCATTTTAACATG
Protein		Refseq >NP_989121\|cyclin B1 [Xenopus (Silurana) tropicalis] MSLRITRNMMANAENNVKTTVAGKRVVATKPVLRPRTALGDIGNKAELKVPAKKELKPAVKAIKKVKPVDKVLEPLKVREENVCPKPAQVEPSSPSPMETSGCLPDELCQAFSDVLIQVKDVDADDDGNPMLCSEYVKDIYCYLRSLENAQAVRQNYLHGQEVTGNMRAILIDWLVQVQMKFRLLQETMFMTVGIIDRFLQDHPVPKNQLQLVGVTAMFLAAKYEEMYPPEIGDFTFVTDHTYTKAQIRDMEMKVLRVLKFAIGRPLPLHFLRRASKIGEVTAEQHSLAKYLMELVMVDYDMVHYSPSQIAAAASCLSLKILNTGEWTPTMHHYMAYFEDDLVPVMQHMAKNIIKVNKGLTKHLTVKNKYASSKQMKISMIPQLRSDVVVELARPLM	Refseq >NP_001081266\|G2/mitotic-specific cyclin-B1 [Xenopus laevis] MSLRVTRNMLANAENNVKTTLAGKRVVATKPGLRPRTALGDIGNKAEVKVPTKKELKPAVKAAKKAKPVDKLLEPLKVIEENVCPKPAQVEPSSPSPMETSGCLPDELCQAFSDVLIHVKDVDADDDGNPMLCSEYVKDIYAYLRSLEDAQAVRQNYLHGQEVTGNMRAILIDWLVQVQMKFRLLQETMFMTVGIIDRFLQEHPVPKNQLQLVGVTAMFLAAKYEEMYPPEIGDFTFVTDHTYTKAQIRDMEMKILRVLKFAIGRPLPLHFLRRASKIGEVTAEQHSLAKYLMELVMVDYDMVHFTPSQIAAASSCLSLKILNAGDWTPTLHHYMAYSEEDLVPVMQHMAKNIIKVNKGLTKHLTVKNKYASSKQMKISTIPQLRSDVVVEMARPLM UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.4379 [+] Str.36299 Str.25119 Str.45114 Str.45215 Str.45265 Str.45272 Str.47614 Str.54591	Xl.21952
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		28 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CCNB1
mouse		MGI	Ccnb1	All(4) Targeted, other(3) Targeted, knock Out(1)
zebrafish		ZFIN	ccnb1	3 Lines(s)

Publications
First:		Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis. [Nature 1989]
Most recent:		The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles. [Biophys Chem 2013]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:		regulation of progression through cell cycle
Cellular Component:		nucleus
EC:
KOG:		[D] Cyclin B and related kinase-activating proteins

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.4379.2.S1_a_at [+] Str.25444.1.A1_at Str.25119.1.A1_at Str.45215.1.A1_x_at Str.45233.1.A1_at Str.45265.1.A1_at Str.45272.1.A1_x_at Str.45637.1.A1_x_at Str.47614.1.A1_at Str.47614.1.A1_x_at	Xl.21952.1.S1_at [+] Xl.25675.1.A1_at
Affymetrix 2.0			Xl2.4297.2.S1_a_at [+] Xl2.21952.1.S1_at Xl2.25675.1.A1_at

Symbol legend[+]