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Summary Expression Gene Literature (1) GO Terms (23) Nucleotides (139) Proteins (30) Interactants (415) Wiki
XB-GENEPAGE- 5768571

Gene Symbol: lrrk2

Gene Name: leucine-rich repeat kinase 2

Synonyms:
Add Xenopus synonyms , Nomenclature history

Gene Function: tyrosine kinase

Protein Function:


Interactants: Loading ...

OMIM Disease Associations: PARKINSON DISEASE 8, AUTOSOMAL DOMINANT; PARK8
 
Xenbase Gene ID XB-GENE-5768572 XB-GENE-6252262 XB-GENE-17342223
Gene Symbol lrrk2 lrrk2.L lrrk2.S
Chromosome Chr03 chr3L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.38502 Xl.48462
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lrrk2 lrrk2.L lrrk2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LRRK2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Lrrk2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR lrrk2 ZFIN Ensembl
chicken
GEISHA LRRK2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway. [Mol Neurodegener 2017]
Most recent:
View All Papers 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 20 terms 5 terms 0 term
PANTHER lrrk2
KEGG Pathways K08844
KOG [T] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Affymetrix 1.0 Str.52080.1.S1_at [+]
Affymetrix 2.0 Xl2.48462.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556