Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (219) GO Terms (30) Nucleotides (251) Proteins (32) Interactants (640) Wiki
XB-GENEPAGE-5900654
Gene Symbol:
cdk4

Gene Name:
cyclin-dependent kinase 4

Synonyms:
xcdk4 ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Probably involved in the control of the cell cycle.



Interactants:
Loading ...

Diseases: 


OMIM:
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 3; CMM3

External Links:
 
Xenbase Gene ID XB-GENE-5900655 XB-GENE-17346834 XB-GENE-5900736
Gene Symbol cdk4 cdk4.L cdk4.S
Chromosome Chr2 chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 549496
379406
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdk4 cdk4.L cdk4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CDK4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdk4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdk4 Ensembl
zebrafish
ZFIN, AGR cdk4 ZFIN Ensembl
chicken
fruit fly
FLYBASE Cdk4 Ensembl
worm
Publications
First Inhibition of cyclin-dependent kinases by purine analogues., Eur J Biochem 1994  
Most Recent Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Cancers (Basel) 2020                        
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 0 term 6 terms
PANTHER cdk4
KEGG Pathways K02089 K02089
KOG [R] Protein kinase PCTAIRE and related kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdk4
ORFs cdk4.L ORF1
Clones Horizon Source BioScience EXRC Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list