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Summary Expression Gene Literature (84) GO Terms (16) Nucleotides (67) Proteins (32) Interactants (307) Wiki
XB-GENEPAGE-483232
Gene Symbol:
sox18

Gene Name:
SRY-box 18

Synonyms:
xSox18alpha , xSox18beta , xsox18 , sox18-a , sox18-b ( Add synonyms , Nomenclature history )

Gene Function:
HMG-box transcription factor

Protein Function :
Probable transcription factor. Binds to the consensus DNA sequence 5'-AACAAT-3'. Also binds 5'-CACAAT-3' and 5'-AATAAT-3' with similar affinity.



Interactants:
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Diseases: 


Disease Ontology:
hypotrichosis-lymphedema-telangiectasia-renal defect syndrome [+]

OMIM:
HYPOTRICHOSIS-LYMPHEDEMA-TELANGIECTASIA SYNDROME; HLTS [+]

External Links:
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Xenbase Gene ID XB-GENE-483233 XB-GENE-864957 XB-GENE-6251810
Gene Symbol sox18 sox18.L sox18.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100170185
398226
398227
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sox18 sox18.L sox18.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SOX18 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sox18 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sox18 Ensembl
zebrafish
sox18 Ensembl
chicken
GEISHA SOX18 Ensembl
fruit fly
worm
Publications
First Molecular cloning and characterization of human SOX17., Int J Mol Med 2002  
Most Recent Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos., Nat Commun 2019                                            
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 3 terms 5 terms
PANTHER sox18
KEGG Pathways K09270 K09270 K09270
KOG [K] HMG-box transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sox18
Morpholinos sox18 MO1 sox18 MO1 sox18 MO1
ORFs sox18.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience EXRC Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list