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Summary Expression Gene Literature (71) GO Terms (13) Nucleotides (240) Proteins (48) Interactants (839) Wiki
Gene Symbol:

Gene Name:
POU class 2 homeobox 1

OTF-1 , NF-A1 , XOct1 , oct1 , pou2f1r , oct-1 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and histone H2B. Acts downstream of Notch signaling du...[+]

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External Links:
Xenbase Gene ID XB-GENE-853992 XB-GENE-17345040 XB-GENE-853997
Gene Symbol pou2f1 pou2f1.L pou2f1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549091
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein RefSeq Swiss-Prot Swiss-Prot Swiss-Prot
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pou2f1 pou2f1.L pou2f1.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards POU2F1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Pou2f1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Pou2f1 Ensembl
fruit fly
First Anti-OTF-1 antibodies inhibit NFIII stimulation of in vitro adenovirus DNA replication., Nucleic Acids Res 1989  
Most Recent Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Clin Pharmacol Ther 2020  
All View All Papers 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 3 terms 10 terms
PANTHER pou2f1
KEGG Pathways K09364 K09364
KOG [K] Transcription factor OCT-1, contains POU and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pou2f1
Morpholinos pou2f1 MO1 pou2f1 MO1 pou2f1 MO1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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