Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (155) GO Terms (12) Nucleotides (308) Proteins (45) Interactants (315) Wiki
XB-GENEPAGE-978490
Gene Symbol:
sumo1

Gene Name:
small ubiquitin like modifier 1

Synonyms:
ubl1 , sumo-1 , xsumo1 , xsumo-1 , dap1 , gmp1 , pic1 , smt3 , ofc10 , senp2 , smt3c , sumo1-a , sumo1-b ( Add synonyms , Nomenclature history )

Gene Function:
small ubiquitin-like modifier

Protein Function :
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the...[+]


InterPro :
Rad60/SUMO-like dom , Ubiquitin-like domsf , Ubiquitin-like dom

Interactants:
Loading ...

Diseases: 


Disease Ontology:
orofacial cleft

OMIM:
OROFACIAL CLEFT 10; OFC10

External Links:
 
Xenbase Gene ID XB-GENE-978491 XB-GENE-6254630 XB-GENE-978496
Gene Symbol sumo1 sumo1.L sumo1.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448691
399078
779181
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sumo1 sumo1.L sumo1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SUMO1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sumo1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sumo1 Ensembl
zebrafish
ZFIN, AGR sumo1 ZFIN Ensembl
chicken
GEISHA SUMO1 Ensembl
fruit fly
worm
Publications
First Molecular cloning of the human CAK1 gene encoding a cyclin-dependent kinase-activating kinase., Oncogene 1994  
Most Recent A deficiency in SUMOylation activity disrupts multiple pathways leading to neural tube and heart defects in Xenopus embryos., BMC Genomics 2019                
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 7 terms 5 terms
PANTHER sumo1
KEGG Pathways K12160 K12160 K12160
KOG [O] Ubiquitin-like proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sumo1
Antibodies SUMO1 Ab1 , SUMO1 Ab2 SUMO1 Ab1 , SUMO1 Ab2 SUMO1 Ab1 , SUMO1 Ab2
Morpholinos sumo1 MO1 sumo1 MO1 sumo1 MO1
ORFs sumo1 ORF1 sumo1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list