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Summary Expression Gene Literature (109) GO Terms (22) Nucleotides (123) Proteins (49) Interactants (35) Wiki
XB-GENEPAGE-979544
Gene Symbol:
ccno

Gene Name:
cyclin O

Synonyms:
ccnu , udg2 , ung2 , cyclin-o ( Add synonyms , Nomenclature history )

Gene Function:
Cyclin B and related kinase-activating proteins

Protein Function :
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of mcidas to promote mother...[+]


InterPro :
Cyclin , Cyclin-like sf , Cyclin C-dom , Cyclin N [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Kartagener syndrome [+]

OMIM:
CILIARY DYSKINESIA, PRIMARY, 29; CILD29

External Links:
 
Xenbase Gene ID XB-GENE-979545 XB-GENE-979551 XB-GENE-17332754
Gene Symbol ccno ccno.L ccno.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 407893
734946
734931
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ccno ccno.L ccno.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CCNO OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ccno MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ccno Ensembl
zebrafish
ccno Ensembl
chicken
GEISHA CCNO Ensembl
fruit fly
worm
Publications
First Xenopus CENP-A assembly into chromatin requires base excision repair proteins., DNA Repair (Amst) 2005  
Most Recent TRRAP is a central regulator of human multiciliated cell formation., J Cell Biol 2018                          
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 7 terms 7 terms
PANTHER ccno
KEGG Pathways K10861 K10861 K10861
KOG [D] Cyclin B and related kinase-activating proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ccno
Morpholinos ccno MO1 ccno MO1 ccno MO1
ORFs ccno ORF1 ccno.L ORF1 ccno.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list