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acta2xenopus   

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Experiment details for acta2

Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus.



Gene Clone Species Stages Anatomy
acta2.L laevis NF stage 45 to NF stage 46 intestine , smooth muscle

  FIG. 6. Features of the mesentery with expression of SmoM2. (A) Histological analysis shows a two-cell layer thick mesentery in control embryos that is contiguous with the wall of the gut (arrows). (B) In SmoM2-expressing embryos at Nieuwkoop–Faber Stage 45/46, this mesentery shows abnormal thickening in many areas (arrows). (C) The mesenchyme in Smo-injected embryos shows intense staining with an antibody directed against smooth muscle actin. (D) Embryos expressing SmoM2 show much weaker staining.